Astral Codex Ten Podcast

https://slatestarcodex.com/2015/09/16/cardiologists-and-chinese-robbers/ I. It takes a special sort of person to be a cardiologist. This is not always a good thing. You may have read about one or another of the "cardiologist caught falsifying test results and performing dangerous unnecessary surgeries to make more money" stories, but you might not have realized just how common it really is. Maryland cardiologist performs over 500 dangerous unnecessary surgeries to make money. Unrelated Maryland cardiologist performs another 25 in a separate incident. California cardiologist does "several hundred" dangerous unnecessary surgeries and gets raided by the FBI. Philadelphia cardiologist, same. North Carolina cardiologist, same. 11 Kentucky cardiologists, same. Actually just a couple of miles from my own hospital, a Michigan cardiologist was found to have done $4 million worth of the same. Etc, etc, etc. My point is not just about the number of cardiologists who perform dangerous unnecessary surgeries for a quick buck. It's not even just about the cardiology insurance fraud, cardiology kickback schemes, or cardiology research data falsification conspiracies. That could all just be attributed to some distorted incentives in cardiology as a field. My point is that it takes a special sort of person to be a cardiologist.

https://slatestarcodex.com/2020/05/12/studies-on-slack/ I. Imagine a distant planet full of eyeless animals. Evolving eyes is hard: they need to evolve Eye Part 1, then Eye Part 2, then Eye Part 3, in that order. Each of these requires a separate series of rare mutations. Here on Earth, scientists believe each of these mutations must have had its own benefits – in the land of the blind, the man with only Eye Part 1 is king. But on this hypothetical alien planet, there is no such luck. You need all three Eye Parts or they're useless. Worse, each Eye Part is metabolically costly; the animal needs to eat 1% more food per Eye Part it has. An animal with a full eye would be much more fit than anything else around, but an animal with only one or two Eye Parts will be at a small disadvantage. So these animals will only evolve eyes in conditions of relatively weak evolutionary pressure. In a world of intense and perfect competition, where the fittest animal always survives to reproduce and the least fit always dies, the animal with Eye Part 1 will always die – it's less fit than its fully-eyeless peers. The weaker the competition, and the more randomness dominates over survival-of-the-fittest, the more likely an animal with Eye Part 1 can survive and reproduce long enough to eventually produce a descendant with Eye Part 2, and so on.

https://slatestarcodex.com/2020/05/05/book-review-contest-call-for-entries/ Your mission, should you choose to accept it, is to write a book review and send it to me at scott[at]slatestarcodex[dot]com before August 5th 2020. Interested? Here's the small print (written in normal-sized print, for your convenience): Pick a book, then write a review similar to my SSC book reviews (examples). I'm mostly expecting reviews of nonfiction, but I guess you could review fiction if you really wanted and had something interesting to say beyond just "here's the plot and I thought it was good". I'll choose some number of finalists – probably around five, but maybe more or less depending on how many I get – and publish them on the blog, with full attribution, just like with the adversarial collaborations. Then readers will vote for the best, just like with the adversarial collaborations. First place will get at least $1000, second place $500, third place $250 – I might increase those numbers later on. Some winners may also get an invitation to pitch me any other pieces they have that they think would make good SSC posts. I may also release non-finalist entries somewhere else so people can read them – if you strongly object to me making your entry public, let me know.

https://slatestarcodex.com/2015/08/17/the-goddess-of-everything-else-2/ [Related to: Specific vs. General Foragers vs. Farmers and War In Heaven, but especially The Gift We Give To Tomorrow] They say only Good can create, whereas Evil is sterile. Think Tolkien, where Morgoth can't make things himself, so perverts Elves to Orcs for his armies. But I think this gets it entirely backwards; it's Good that just mutates and twists, and it's Evil that teems with fecundity. Imagine two principles, here in poetic personification. The first is the Goddess of Cancer, the second the Goddess of Everything Else. If visual representations would help, you can think of the first with the claws of a crab, and the second a dress made of feathers of peacocks. The Goddess of Cancer reached out a clawed hand over mudflats and tidepools. She said pretty much what she always says, "KILL CONSUME MULTIPLY CONQUER." Then everything burst into life, became miniature monsters engaged in a battle of all against all in their zeal to assuage their insatiable longings. And the swamps became orgies of hunger and fear and grew loud with the screams of a trillion amoebas.

https://slatestarcodex.com/2020/04/29/predictions-for-2020/ At the beginning of every year, I make predictions. At the end of every year, I score them. So here are a hundred more for 2020. Rules: all predictions are about what will be true on January 1, 2021. Some predictions about my personal life, or that refer to the personal lives of other people, have been redacted to protect their privacy. I'm using the full 0 – 100 range in making predictions this year, but they'll be flipped and judged as 50 – 100 in the rating stage, just like in previous years. I've tried to avoid doing specific research or looking at prediction markets when I made these, though some of them I already knew what the markets said. Feel free to get in a big fight over whether 50% predictions are meaningful. CORONAVIRUS: 1. Bay Area lockdown (eg restaurants closed) will be extended beyond June 15: 60% 2. …until Election Day: 10% 3. Fewer than 100,000 US coronavirus deaths: 10% 4. Fewer than 300,000 US coronavirus deaths: 50% 5. Fewer than 3 million US coronavirus deaths: 90% 6. US has highest official death toll of any country: 80% 7. US has highest death toll as per expert guesses of real numbers: 70% 8. NYC widely considered worst-hit US city: 90%

https://slatestarcodex.com/2020/04/27/give-yourself-gout-for-fame-and-profit/ I. Actually, no. You should not do this. Most of you were probably already not doing this, and I support your decision. But if you want a 2000 word essay on some reasons to consider this, and then some other reasons why those reasons are wrong, keep reading. Gout is a disease caused by high levels of uric acid in the blood. Everyone has some uric acid in their blood, but when you get too much, it can form little crystals that get deposited around your body and cause various problems, most commonly joint pain. Some uric acid comes from chemicals found in certain foods (especially meat), so the first step for a gout patient is to change their diet. If that doesn't work, they can take various chemicals that affect uric acid metabolism or prevent inflammation. Gout is traditionally associated with kings, probably because they used to be the only people who ate enough meat to be affected. Veal, venison, duck, and beer are among the highest-risk foods; that list sounds a lot like a medieval king's dinner menu. But as kings faded from view, gout started affecting a new class of movers and shakers. King George III had gout, but so did many of his American enemies, including Franklin, Jefferson, and Hancock (beginning a long line of gout-stricken US politicians, most recently Bernie Sanders). Lists of other famous historical gout sufferers are contradictory and sometimes based on flimsy evidence, but frequently mentioned names include Alexander the Great, Charlemagne, Leonardo da Vinci, Martin Luther, John Milton, Isaac Newton, Ludwig von Beethoven, Karl Marx, Charles Dickens, and Mark Twain.

https://slatestarcodex.com/2020/04/24/employer-provided-health-insurance-delenda-est/ My last post didn't really go to deep into why I dislike the way we do health insurance so much. Of course, there are the usual criticisms based on compassion and efficiency. Compassion because poor people can't get access to life-saving medical care. Efficiency because it's ruinously expensive compared to every other system around. I agree with these arguments. And they're strong enough that asking whether there are any other reasons is kind of like the proverbial "But besides that, Mrs. Lincoln, how did you like the play?" But I had already internalized the compassion and efficiency critiques before becoming a doctor. After starting work, I encountered new problems I never would have expected, ones which have yet to fade into the amorphous cloud of injustices we all know about and mostly ignore. Most of my patients have insurance; most of them are well-off; most of them are intelligent enough that they should be able to navigate the bureaucracy. Listen to the usual debate around insurance, and you would expect them to be the winners of our system; the rich people who can turn their financial advantage into better care. And yet barely a day goes by without a reminder that it doesn't work this way. Here are some people I have encountered – some of them patients, some of them friends – who have made me skeptical that our system works for anyone at all:

https://slatestarcodex.com/2020/04/20/the-amish-health-care-system/ I. Amish people spend only a fifth as much as you do on health care, and their health is fine. What can we learn from them? A reminder: the Amish are a German religious sect who immigrated to colonial America. Most of them live apart from ordinary Americans (who they call "the English") in rural communities in Pennsylvania and Ohio. They're famous for their low-tech way of life, generally avoiding anything invented after the 1700s. But this isn't absolute; they are willing to accept technology they see as a net positive. Modern medicine is in this category. When the Amish get seriously ill, they will go to modern doctors and accept modern treatments. The Muslims claim Mohammed was the last of the prophets, and that after his death God stopped advising earthly religions. But sometimes modern faiths will make a decision so inspired that it could only have come from divine revelation. This is how I feel about the Amish belief that health insurance companies are evil, and that good Christians must have no traffic with them.

https://slatestarcodex.com/2020/04/17/depression-the-olfactory-perspective/ Depressed people have worse sense of smell, and people with worse sense of smell are more likely to get depressed. Kohli 2016 tries to figure out what's going on. They review six studies testing how well depressed people can smell things. Most use something called "The Sniffin' Sticks Test" (really!) where people are asked to say which of two sticks has an odor; the strength of the odorous one is then decreased until the subject can no longer consistently get it right. This determines olfactory threshold – how sensitive the subject's smell is. Depressed subjects did marginally (but significantly) worse on this test than controls (6.31 ± 1.38 vs. 6.78 ± 0.88; P = 0.0005) – I think this corresponds to an effect size of about 0.2. They also do a couple more tests to see if depressed people are worse at identifying odors and get similarly small results. Also, some neuroimaging studies directly correlate depression and olfactory bulb volume, and find that olfactory areas of depressed people's brains shrink.

https://slatestarcodex.com/2020/04/14/a-failure-but-not-of-prediction/ I. Vox asks What Went Wrong With The Media's Coronavirus Coverage? They conclude that the media needs to be better at "not just saying what we do know, but what we don't know". This raises some important questions. Like: how much ink and paper is there in the world? Are we sure it's enough? But also: how do you become better at saying what you don't know? In case you've been hiding under a rock recently (honestly, valid) the media not only failed to adequately warn its readers about the epidemic, but actively mocked and condescended to anyone who did sound a warning. Real Clear Politics has a list of highlights. The Vox tweet saying "Is this going to be a deadly pandemic? No." Washington Post telling us in February "Why we should be wary of an aggressive government reponse to coronavirus (it might "scapegoat marginalized populations"). The Daily Beast complaining that "coronavirus, with zero American fatalities, is dominating headlines, while the flu is the real threat". The New York Times, weighing in with articles like "The pandemic panic" and "Who says it's not safe to travel to China". The constant attempts to attribute "alarmism" over the virus to anti-Chinese racism. Etc, etc, etc. One way people have summed this up is that the media (and the experts they relied on) did a terrible job predicting what would happen. I think this lets them off too easy.