Gladden Longevity Podcast

On this episode, we're featuring a special RAAD Fest discussion from last year between Dr. Gladden and Dr. Jeffry Life, a doctor who has focused his practice on healthy aging and helping patients avoiding heart attacks and strokes. He incorporates the Bale-Doneen Method (learn more in the book Beat the Heart Attack Gene) in his treatment plans, which is about aggressively looking for vascular inflammation that causes heart disease and working to stop it. They discuss some of the testing that can be done to identify vascular risk factors, which fall outside of the normal insurance-based model of healthcare. Dr. Life describes what he does for himself to improve his own health, fitness and longevity. He and Dr. Gladden discuss hormone replacement and HGH and when it is appropriate treatment. Special Guest: In 1997, Dr. Jeffry Life was a board-certified family practice physician who was 59 years old, overweight, poorly conditioned body and in rapidly declining health. He couldn't tie his shoes without losing his breath. His stomach was huge, his muscles and joints ached, and he was miserable. He decided it was time to focus some much-needed medical attention on himself. Not knowing where to start, he began reading fitness magazines and came across an article that featured the winners of the Body-for-LIFE contest. He followed a low-glycemic/low-fat diet, took supplements, and plunged into a heavy exercise regimen with help from a former Navy Seal personal trainer, Ernie Baul. At the end of 1998, at 60 years of age and after consistently eating right and training right, he became the GRAND CHAMPION in Bill Phillip's 1998 Body-for-LIFE contest. He continued his commitment to the Fitness Lifestyle, yet despite my hard work and dedication, he started losing ground as he edged toward 63. He was slowly losing muscle mass, and strength and was regaining body fat. His energy level was waning, as was his libido. He had heard about the Anti-Aging Medicine Movement, so he investigated further. He learned a whole new level of protocols and philosophies and immediately agreed to become a patient. Within a couple weeks, Life started to see and feel a marked shift in his body, mind and spirit. He was once again becoming a vibrant, healthy and happy man. It was life-altering and became the catalyst that moved him from Family Medicine to healthy aging medicine. He wanted every man and woman that struggled as he had to have hope for a better life. Today, at 78 years of age, he is in the best shape of his life. He's in the gym 5 days a week. He has a thriving practice in Charleston, West Virginia (The Life Center for Healthy Aging), and he has authored three books: The Life Plan, Mastering the Life Plan and The Life Plan Diet. Learn more at https://www.drlife.com/. Follow him on Twitter @DrLife, Instagram @drjlife and Facebook.

On this episode, Dr. Gladden and Mark dive into the subject of cancer, inviting Dr. Thomas Incledon of Causenta® Wellnessto talk about a new model of treating cancer patients outside of traditional medicine. It's often difficult for doctors within the standard healthcare system to break out of typical thinking about cancer treatments. This often prevents new discoveries from being applied to treatment plans, especially when reimbursement is a priority. Dr. Incledon discusses some alternative treatments they are using at Causenta, including light-based therapy, ozone therapy, and oxidative stress. They also pay careful attention to the order in which they implement therapies for patients, as well as how the rest of the body plays a role in treatment. They talk about studying different strategies that challenge the metabolic pathways of cancer and what that means for other health management during treatment. Every person is different, and that must be taken into account when planning out therapy. Dr. Incledon suggests what things a person should do first when they receive a cancer diagnosis and what to ask their doctor. He also recommends actions we can take to help reduce our risk for cancer, including getting good sleep, getting outside, drinking enough fluid, exercising and eating a variety of colors in your diet. Ask yourself, "For those dealing with cancer directly or with a loved one, what are you doing outside of mainstream care to supplement treatment?" About the guest: Dr. Thomas Incledon, holds a B.S. in Exercise Science, B.S. in Nutrition, M.S. in Kinesiology, and Ph.D. in Exercise Physiology. Since 1989, Dr. Tom Incledon has been recognized as one of the world's leading experts in the areas of human health and athletic performance. He is the founder and CEO of Causenta Wellness, a cutting-edge wellness and cancer treatment center in Scottsdale, Arizona. Dr. Tom helps individuals from all walks of life to understand the cause of there health issues and move toward optimal health. His clinic helps patients improve their quality of life, and provides transformational results for those seeking to improve their athletic performance. He belongs to over 30 different scientific organizations and reviews several peer-reviewed journals. Dr. Tom is one of the most sought-after healthcare providers in the United States. Dr. Tom Incledon's life goal is stated in his own words, "eradicating disease from the face of the Earth." This pursuit has led him to pioneer some of the most revolutionary cancer treatments in the history of medicine. As an example, measuring every gene in a person AND every gene in their cancer cell AND over 1000 cancer biomarkers, then take that data to determine the best strategy to help that person beat cancer. His strategies help patients overcome cancer quickly, painlessly, and dramatically improve their quality of life—placing Causenta at the forefront of cancer treatment. Known as "The World's Strongest Sports Scientist," he has achieved recognition based on his own experience with health and fitness. His extensive academic understanding of the human body supports his expertise. Dr. Tom set national records in Strongman Competitions. He is best known for completing 19 reps in the 200 lb. Axle Press. On the supplement and nutrition front, Dr. Incledon is the "go-to" advisor for many of the world's most popular dietary supplement/nutraceutical companies and health magazines. (Including- Men's Health and Muscle & Fitness). More specifically, he excels in creating effective formulations. Follow Causenta Wellness on Facebookand Instagram.

We welcome back Dr. Bill Andrews of Sierra Sciences to further expand on research into telomeres and telomerase for extending lifespan. Dr. Andrews explains how the existing research shows that there are potential telomere lengtheners, but they are still losing the tug-of-war with telomere shortening. He talks about how lack of funding may be the primary obstacle for telomere breakthroughs. Dr. Andrews also explains the actual link between telomerase and cancer, which is often misunderstood. They also consider the implications of gene therapy and gene editing in terms of producing telomerase. The main cause of telomere shortening is a lack of telomerase, though some things accelerate the process, like oxidative stress and inflammation. The doctors list a number of things people can do to reduce oxidative stress, including lifestyle changes and supplements that can help. Learn more about products by defytime® here. For information on IsaGenesis®/Product B, visit here. Learn more about Life Length: https://lifelength.com/ Learn more about RAADfest. On This Week on Longevity Science, Robb Taylor talks about the potential of Vitamin C to help in cancer therapy. Read more on the blog. Ask yourself: How serious am I about altering my lifestyle to protect my telomere lengths, and how much of my life, thought process and financial resources should I devote to this? Special Guest: Dr. Bill Andrews is the President and CEO of Sierra Sciences. As a scientist, athlete and executive, he continually pushes the envelope and challenges convention. He has been featured in Popular Science, The Today Show and numerous documentaries on the topic of life extension, including, most recently, the movie The Immortalists in which he co-stars with Aubrey de Grey. Since 1981, Bill Andrews has focused on finding ways to extend the human lifespan and healthspan through telomere maintenance. As one of the principal discoverers of both the RNA and protein components of human telomerase, Dr. Andrews was awarded 2nd place as "National Inventor of the Year" in 1997. He earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. He has served as Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Berlex Biosciences and at Geron Corporation, and Director of Technology Development at EOS Biosciences. He is also a named inventor on over 50+ US issued patents on telomerase and author of numerous scientific research studies published in peer reviewed scientific journals. Bill is also an avid ultra-marathon runner. Born December 10, 1951, he regularly competes in 100k and 100+ mile runs often finishing at the top of his age group. These grueling races have taken him all over the world to race in some of the most extreme environments, from Death Valley to the Himalayas. His running is presently featured in the movie The High. You can order his books Bill Andrews on Telomere Basics: Curing Aging and Telomere Lengthening: Curing All Disease Including Aging and Cancer now. Follow Sierra Sciences on Facebook and Twitter: @SierraSciences.

On this episode, we're featuring a special RAAD Fest discussion from last year between Dr. Gladden and Dr. Bill Andrews, one of the leading scientists in telomere research. Dr. Andrews explains how telomeres work and how the length impacts your life expectancy. Put simply, longer telomeres are always good, and the shortening of them is always associated with disease and cell death. Dr. Andrews mentions the book, The Telomere Effect by Dr. Elizabeth Blackburn and Dr. Elissa Epel, regarding slowing the shortening of telomeres. They discuss the research into telomerase activators and the hope for working toward lengthening telomeres. He discusses TAM-818 and TA-65® as means to reduce the rate of telomere shortening and offers up his top three suggestions on what people can do to extend their lives. Special Guest: Dr. Bill Andrews is the President and CEO of Sierra Sciences. As a scientist, athlete and executive, he continually pushes the envelope and challenges convention. He has been featured in Popular Science, The Today Show and numerous documentaries on the topic of life extension, including, most recently, the movie The Immortalists in which he co-stars with Aubrey de Grey. Since 1981, Bill Andrews has focused on finding ways to extend the human lifespan and healthspan through telomere maintenance. As one of the principal discoverers of both the RNA and protein components of human telomerase, Dr. Andrews was awarded 2nd place as "National Inventor of the Year" in 1997. He earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. He has served as Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Berlex Biosciences and at Geron Corporation, and Director of Technology Development at EOS Biosciences. He is also a named inventor on over 50+ US issued patents on telomerase and author of numerous scientific research studies published in peer reviewed scientific journals. Bill is also an avid ultra-marathon runner. Born December 10, 1951, he regularly competes in 100k and 100+ mile runs often finishing at the top of his age group. These grueling races have taken him all over the world to race in some of the most extreme environments, from Death Valley to the Himalayas. His running is presently featured in the movie The High. You can order his books Bill Andrews on Telomere Basics: Curing Aging and Telomere Lengthening: Curing All Disease Including Aging and Cancer now.

On this episode, Mark and Dr. Gladden discuss the many ways your true biological age can be determined, your longevity possibly predicted – and what you can do to improve these factors. Mark talks about his experience with an ozone therapy machine and Vasper at Dr. Gladden's clinic. Gladden explains the benefits of ozone in the body and how the therapy works, including increasing a molecule called NAD, which allows the cells to make more ATP. Telomeres are the "timekeepers" for the cell, caps at the ends of your chromosomes. You can somewhat predict the span of your life by the length of your telomeres, but you can do things to improve telomere lengths. A telomere length can show you're physiologically younger or older than your chronological age. One company that does a thorough test on telomere length is Life Length. Cell mitochondria make ATP, or energy for cells. Cancer develops in cells that are abnormal and energy-starved. Cancer cells turn on telomerase to re-lengthen their telomeres, possibly making them immortal. Your lifestyle significantly impacts if you are shortening or lengthening your telomeres. Exercise, fish oil, meditation, Astragalus (via cycloastragenol, for instance) are tools to preserve the length of your telomeres. Molecular hydrogen can protect against radiation damage to telomeres. They consider other ways to judge a person's true age, like arterial age, bone age and brain age. They discuss the mindset that one should develop that places a high value on your health. Many people sacrifice their health in an effort to get more money, but then they spend much of that money trying to recover their health later in life. Mark talks about this in terms of how we experience the life we have, at different ages, and he stresses the importance of making novelty a priority, so our life feels fuller for longer. Robb Taylor and Dr. Gladden also discuss 5 alternative cancer therapies your doctor might not tell you about. To read a more in-depth article, visit the blog. Ask yourself, "What can you do to take care of your real asset, your telomeres?" Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

On this episode that focuses on men's sexual health, Dr. Gladden, Mark and Robb explore the importance of sexual health on body, mind and longevity. Statistically, people who have more sex live longer, and your ability to perform sexually is a great barometer of the health of your cardiovascular and nervous systems. They discuss some of chemical responses in the body that occur before, during and after sex, including the release of nitric oxide and oxytocin. There are many ways we can sabotage our own sex lives, including consuming poor diets, alcohol and other harmful substances. Dr. Gladden talks about how essential nitric oxide is for sexual health and recommends some nitrate-rich foods that can help improve it. Gladden references products, BeetElite® and Neo40®, from https://www.humann.com/, which can be good supplements to increase your dietary nitrates. They discuss how popular erectile dysfunction drugs like Cialis®, Levitra® and Viagra® work and explain that they'll still only be as good as the nitric oxide we already have in our bodies. Hormones balance is critical not only for sexual health, but for overall health. It's not just about hormones levels the blood but also the metabolites that show up in the urine you expel. Gladden references the DUTCH (dried urine test for comprehensive hormones) test that he uses in his practice to examine hormone levels for patients. When critical hormone levels go down, we lose our ability to handle our environment, perform sexually and end up at risk for cancers and other physiological problems. They consider the different ways testosterone can be delivered as a supplement to aid in libido and sexual health. Dr. Gladden and Mark briefly talk about peptides, short chains of amino acids that are being experimented with for their health benefits. Melanotan and PT-141 may help improve libido and erectile function; Epithalon may improve orgasmic quality for people. Sex begins in the mind, so if there are challenges, it's essential to heal the biology as well as the psychology. Mark describes how neuro-associations can lead to difficult-to-break post-traumatic stress responses, and he explains when hypnosis might be able to help you. They consider how pornography can affect a person's ability to perform sexually, on chemical and psychological levels. When it comes to improving your sex life with your partner, continuous communication and engagement is essential for long-term compatibility. Ask yourself, "What can I do today to move in a direction that optimizes my biology and my psychology for my sexual health?"

First and foremost, it's crucial to envision that you'll still be able to do athletic activities when you're into your 80s, 90s and beyond. Dr. Gladden explains that he's getting older chronologically, but he's getting younger physiologically – and he speaks on his mindset that sets him up for success. The Doctor recommends getting a cardio pulmonary stress test before starting a new exercise plan, to avoid injury or catastrophic health problems like a heart attack. Another test that helps identify potential physiological problems ahead of time is the MET-TEST. They discuss different kinds of physical training, including HIIT (high intensity interval training) and the need to develop a cardio baseline by exercising at a slower heartrate over an extended period of time. The recommend spreading out the kind of workouts that you do, to spare yourself from injury and build different muscle groups. Gladden provides some other tips on preventing injury, as well as how to cope and maintain strength if you do get injured. Gladden also talks about Fortetropin®, a myostatin inhibitor that helps people build muscle by decreasing the way muscle is broken down. They talk about the benefits of "loading your frame" to improve skeletal, tendon and ligament strength, then they discuss balance training and how to incorporate it into your life. Creating a habit of doing something every day is much better for your body and mind rather than only pushing your body to its limits once or twice a week. Play is also critical when you exercise, for keeping your mind and body youthful. In This week in Longevity Science, they discuss Klotho, what is being called "the longevity protein," as it could one day play a vital role in helping treat potentially deadly conditions. For more information on the subject, visit https://wisdomtolive.com/longevity-protein-could-save-lives-improve-health/. Key takeaways: Before you start an exercise plan, be safe, get tested, and work out smart to prevent injury. For your mindset, focus on being fast, agile and strong at every age. Develop the habit of exercise in small, sustaining steps. Variety in exercise is a necessity. Keep exercise fun and try new things. For this week's empowering question, ask yourself, "How would you change your training now if you want to be engaged in your favorite activity years, or even decades, from now?"

This week's episode focuses on the difference between what your doctor's visit should sound like versus the few minutes the average doctor spends with a patient. Dr. Gladden explains why these short visits prevail in the current health care system, and they discuss how you need to change your mindset about who is responsible for keeping you healthy. They talk about the dangers of NSAIDs and a how most people use them. When anti-inflammatory drugs are used regularly, the root cause of the inflammation is often not addressed and is allowed to continue to cause damage. They discuss inflammation and how it leads to aging. This Week in Longevity Science also focuses on the average time a doctor spends with patients, questioning how much your healthcare provider can actually address your well-being in that short time. Dr. Gladden recommends how to get more out of your visits. For a unique perspective, Dr. Gladden goes through real results from some of Mark's own tests after a recent visit – showing step by step how this critical set of data can be used to extend Mark's lifespan.

As 2018 begins, there are things to keep in mind as you set goals for improving health and happiness. New Year's resolutions need to be measurable and have a timetable. Also, we need to create good habits to be able to achieve these goals. Fostering small, good habits set you up for greatness and also give you faster feedback on how well you're doing. As people dive into new diets at the start of the year, Dr. Gladden and Mark talk about how no diet is a perfect fit for everyone. You need to pay attention to your own genetic make-up or possibly put yourself at risk. This week in longevity science, Robb talks about gene editing and its possibilities for erasing genetic medical conditions. For more information on CRISPR, visit https://www.wired.com/story/what-is-crispr-gene-editing/ and https://gizmodo.com/in-2018-we-will-crispr-human-beings-1821540150. Ask yourself: how can I change my mindset to one that opens up my longevity and human performance in 2018?

Dr. Gregory Fahy is a cryobiologist and biogerontologist. He's credited with a many of the breakthroughs in cryopreservation, and he has been working on finding new ways to use already-approved drugs. Fahy talks about his work with human growth hormone (HGH) and shares the highlights of the results of his first human trials with it. He talks about what happens around age 62-65 for most people that rapidly increases chances of death. Fahy urges people interested in longevity to pay attention to what is on the cutting edge of medicine, he stresses the importance of nicotinamide adenine dinucleotide (NAD) in staying youthful, and he believes there is a profound connection between the immune system and aging. Also on the podcast, Mark explains what he means when he says Americans are eating like we're on death row. Dr. Gladden expands on HGH and considers some of the drawbacks and complications that could occur when it is used as treatment. In This Week in Longevity Science, they discuss peptides as a form of treatment, including how they function in the body and their promising regenerative properties. Research is being done to see how well peptides could work for highly customized medicine, not only for a specific disease but the exact disease within the individual. Ask yourself, "How am I going to learn more about this cutting-edge science in order to change the trajectory of my aging?" About the Guest: Gregory M. Fahy, Ph.D. Dr. Fahy earned his B.S. from the University of California at Irvine in 1972 and his Ph.D. from the Medical College of Georgia in 1977 for work on basic aspects of cryobiology. He spent the next 18 years developing methods for preserving whole organs at cryogenic temperatures at the American Red Cross in Maryland. In 1980, he conceived of preserving organs by vitrification. He published the first proof of principle of this concept in Nature in 1985 using mouse embryos as a model system, an event that led to the wide use of vitrification in academic and commercial animal husbandry as well as in human assisted reproduction. In 1995, he won the Grand Prize for Medicine from INPEX for his invention of the first effective computer-operated equipment for perfusing organs with cryoprotective agents. The same year, he left the Red Cross to become Chief Scientist of two biotechnology companies and the Head of the Tissue Cryopreservation Section of the Transfusion and Cryopreservation Research Program at the Naval Medical Research Institute in Bethesda, Maryland. In 1998, he became the Chief Scientific Officer and Vice President of 21st Century Medicine, where he invented several new principles in cryopreservation that have been extraordinarily effective in practical applications ranging from tissues to whole organs. Dr. Fahy's efforts have recently raised the question of whether human suspended animation might be an attainable goal that could allow the human species to survive in deep time as a result of enabling migration from the earth to other habitats in the cosmos. Dr. Fahy is a sought-after speaker and problem-solver. He is on the Board of Directors of several organizations concerned with cryopreservation or aging, serves on the Editorial Board of Rejuvenation Research, and has served as a reviewer for numerous journals and granting bodies. He has over 20 patents in fields related to cryopreservation, aging, transplantation, metabolic protection, and the reversal of autoimmunity and immunosenescence, and has many publications in the fields of cryobiology, aging, and nanotechnology. He currently serves as Director for Intervene Immune, Inc. Learn more about the projects they are working on and how to become a part of their clinical trials at http://interveneimmune.com/. Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.