OncoPharm

John Bossaer
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Jul 11, 2018 • 17min

Paclitaxel

We discuss paclitaxel, from its discovery to its uses to toxicity and their management as part of our Landmarks in #OncoPharm series. And if you really, really love this drug - you'll learn where to may homage at a historical marker in....
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Jul 4, 2018 • 7min

Happy Fourth!

Our shortest Pod yet! Chemotherapy explosions and photosensitizing antineoplastics are discussed.
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Jun 28, 2018 • 18min

Encorafenib & Binimetinib

The newly FDA-approved BRAF & MEK inhibitors are discussed, along with their possible clinical relevance and some notable differences compared to previously available BRAF & MEK inhibitors.
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Jun 21, 2018 • 18min

The Immunotherapy Two Step

Immunotherapy takes two steps forward (new FDA approvals)....and two steps backwards. These updates in #oncopharm are discussed before ending (11:45) with discussions of venetoclax's expanded approval in CLL, the bevacizumab approval almost 7 years in the making, and late-breaking information on preventing cisplatin ototoxicity.
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Jun 13, 2018 • 16min

Ondansetron Origins

The Landmarks in Oncology Pharmacy series returns with a review of 2 ondansetron studies from 1990, published simultaneously in NEJM.
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Jun 7, 2018 • 24min

Less is More & More

Recapping (some) of the top stories from ASCO18 starting with breast cancer (TAILOR-Rx, PERSEPHONE, SANDPIPER, S0927); then NSCLC (11:35) with Keynote-42 & LOXO-292; then mylemoa (16:50) with a CAR-T update and a new dosing of carfilzomib; before ending (20:30) with CARMENA and PRODIGY-24's new mFOLFIRINOX data for adjuvant pancreatic cancer. Whew!
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May 31, 2018 • 16min

ASCO18 & Under the Radar Abstracts

Previewing this week's ASCO annual meeting and the Plenary Sessions (briefly) and selected abstracts highlighting oncology pharmacy practice.
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May 25, 2018 • 17min

Avatrombopag

Avatrombopag's FDA-approval prompts discussion of both the indication and drug itself. Finally, the publication of the SELECT-D study allows us to dig deeper into the data of a DOAC vs. LMWH in cancer-associated VTE.
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May 19, 2018 • 13min

PERSEPHONE: Bonus Pod

The release of ASCO's 2018 annual abstracts resulted in widespread media coverage of PERSEPHONE, the largest trial yet investigating 6 vs. 12 months of adjuvant trastuzumab in breast cancer. We get into the history of adjuvant trastuzumab studies and what to watch for going forward.
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May 18, 2018 • 12min

Cytarabine

Cytarabine, the 'c' chemotherapy from the sea, is discussed.

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