Big Picture Medicine

Dr Dafydd Loughran trained as a surgeon, before joining Babylon Health as an AI Clinician and then founding Concentric Health. Concentric is digitising the consenting of patients prior to surgery. Essentially, bringing traditional paper consent forms into the 21st century. It started as a surgical consent aide-mémoire which Daf made as a Junior Doctor. He has since raised over $1M and Concentric has been adopted by NHS Trusts such as Imperial College and Chelsea and Westminster. We talk about what it’s like to be CEO as an introvert, the challenges and opportunities in digitising consent and distributed leadership. I hope you enjoy. You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Dr Keith Grimes is Clinical Digital Health & Innovation Director at Babylon Health — essentially, he teaches machines medicine. He’s also a General Practitioner with a special interest in Digital Health & Urgent Care, as well as founder of VR Doctors. We talk about how to get into digital health as a doctor, the importance and unimportance of credentialism in the field, virtual reality and its applications to healthcare and Keith’s experiences with burnout. I hope you enjoy. You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Herman Pontzer is an Associate Professor of Evolutionary Anthropology at Duke University. He studies how our species’ deep past shapes our health and physiology today. He is the author of Burn: New Science Reveals How Metabolism Shapes Your Body, Health, and Longevity. In his book, he follows the Hadza community — a group of people who live in Tanzania and are relatively untouched by the modern sedentary lifestyle. They are hunter gatherers and are about 7 times more active than the average American. You would expect then, that they must be burning thousands of more calories than the typical desk jockey — but they don’t. In fact, on average, they burn the same number of calories as the average American — even when we adjust for height and weight. So what’s going on? You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Dr Imran Mahmud studied Medicine at Oxford, before studying Public Health at Harvard on a Fulbright Scholarship. He then ranked first in the country and entered the Ophthalmology training programme which he then promptly left, joining McKinsey. In 2018 he co-founded NYE Health, raising over £4M. He is now a startup advisor, angel investor and consultant on digital health topics. We speak about leaving Medicine and if the grass is really greener on the other side, how to network, effective decision making and lots more. I hope you enjoy. You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Dr Andrew Vallance-Owen MBE was the Chief Medical Officer of Bupa between 1995–2012. He led work to bring patient reported outcomes into vogue in both the private and public sectors — and he was awarded an MBE in the 2014 Queen’s Birthday Honours. He now has a number of non-executive roles in healthcare, including as Chief Medical Officer of Medicover and on the boards of startups such as Testcard, Jude and Cerina. We talk about his story, what he learnt about crisis management and the future role of private healthcare in the UK. I hope you enjoy. You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Dr Rebecca Pope is the UK Digital & Data Science Innovation Lead at Roche, Senior Research Fellow in AI applied to real healthcare problems at UCL and a Clinical Neuroscientist. She was previously UK Director of Data Science & AI for KPMG and has been voted the Most Influential Woman in UK Tech. Her writing also regularly appears in the Guardian and the Times . We speak about what she learned from moving from research to industry, how AI can actually make Medicine more personal and I ask her why she believes in promoting diversity in STEM and why it isn’t just a case of ‘best person for the job’. I hope you enjoy. You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Dr Michael Moor is a medical doctor doing his PhD in the Machine Learning and Computational Biology Lab at ETH Zurich. Some of his most interesting research looks at predicting sepsis using machine learning approaches. In case you’re unfamiliar, sepsis is a life threatening condition in which the body’s natural defences against an infection go into overdrive. Mortality from septic shock can be up to 50% and every minute counts. In fact, for every hour treatment is delayed — mortality increases by 7.6%. We started off by talking about a paper published in JAMA earlier this year. It assessed a popular sepsis prediction tool and found that it wasn’t very good. It was delivering so many false positives, that doctors would need to assess up to 109 patients flagged by the tool just to find one patient who was actually septic… Michael's Preprint: Predicting Sepsis in Multi-site, Multi-national Intensive Care Cohorts Using Deep Learning Michael Moor*, Nicolas Bennet∗, Drago Plecko∗, Max Horn∗,Bastian Rieck, Nicolai Meinshausen, Peter Bühlmann and Karsten Borgwardt. JAMA 2021 Paper: External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients Andrew Wong, Erkin Otles, Meng; John P. Donnelly, Andrew Krumm, Jeffrey Mccullough, Olivia Detroyer-cooley, Justin Pestrue, Mecon Marie Phillips, Judy Konye, Carleen Penoza, Muhammad Ghous, Karandeep Singh You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Dr Patrick Carroll is the Chief Medical Officer of Hims & Hers — a US Telehealth company which he helped go public in a $1.6 billion dollar SPAC deal. Hims & Hers focuses on many taboo health issues such as sexual health issues, hair loss and mental health. Dr Carroll graduated from Dartmouth Medical School and was previously CMO of Walgreens. We talk about how he got to where he is, what advice he gives to young physician-leaders, why working in primary care was critical for his career and some of the lessons he’s learnt along the way. I hope you enjoy. You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Dr Christopher Kelly is a Senior Research Scientist at Google and a Neonatal Intensive Care Doctor in London. He founded CK Net whilst at Medical School at Cambridge — which was generating £60M in sales for its clients the year before it was acquired as well as founding GettingMarried.co.uk — which was acquired by Prezola in 2016. He is also an Angel Investor, having invested in tech startups such as Deliveroo and Rota.com. We talk about his fascinating winding story — particularly how he was willing to drop it all in pursuit of his passion, we talk about how he was able to build and scale his companies whilst at Medical School and how being a little bit obsessive has paid dividends throughout his career. I hope you enjoy. You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

What does it take to leave Syria during the Civil War and become the first Syrian Rhodes Scholar? Dr Alexey Youssef trained in Medicine in Syria — where he practiced during the Civil War, during which the hospital he worked in was bombed. He then became the first Syrian to gain the prestigious Rhodes Scholarship at Oxford University and then started his PhD in Clinical AI. He has now started his MBA at the Harvard Business School. We talk about some of his research which focuses on building Electronic Health Records in low and middle income countries such as Syria — which has garnered support from the WHO. We also talk about what it was about him and what approaches he used to achieve such amazing success when living and working during the Syrian Civil War. I hope you enjoy. Alex's Podcast: https://potbppodcast.com You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io