Scientific Sense ®

Scientific Sense ® by Gill Eapen: Prof. Maria Castro is Professor of Neurosurgery, and Professor of Cell and Developmental Biology, at the University of Michigan Medical School. Her research program focuses on epigenetic regulation of cancer progression, uncovering the role of oncometabolites in the brain tumor microenvironment (TME), and the development of new therapies for adult and pediatric gliomas. Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Lies I taught in medical school and the truths that can save your life. Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Extra Terrestrials, Fake News and Other Topics.

Scientific Sense ® by Gill Eapen: Prof. Ellen Armour is Professor and Chair of Feminist Theology at Vanderbilt Divinity School. She also directs the Carpenter Program in Religion, Gender and Sexuality. In addition to Seeing and Believing, she is the author of Signs and Wonders: Theology After Modernity that was featured in a previous podcast. Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Decision Options ® by Gill Eapen: Dr. Julio Guerrero who is CEO and founder of Cambridge Research and Technology L.L.C., which provides consulting services and actionable innovations in engineering and scientific fields at any stage of product development. Industries in which he has focused lately include Energy and Biomedical, with concentration in most domains inside Mechanical, Electronics, and Civil engineering. Hydrogen, electrolyzers, fuel cells in O&G field operation Off grid thermal without PVC or wind, and with rocks only Residential geothermal without deep wells Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Scientific Sense ® by Gill Eapen: Prof. Julia Lane is a Professor at the NYU Wagner Graduate School of Public Service. She served in the National AI Research Resources task force and also on the advisory committee on data for evidence building. Her book democratizing our data a manifesto was published in 2020 and she was one of the early guests on this podcast.  Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Scientific Sense ® by Gill Eapen: Ayelet Fishbach is Professor of Behavioral Science and Marketing at the University of Chicago Booth School of Business, and the past president of the Society for the Science of Motivation and the International Social Cognition Network (ISCON).   You think failure is hard? So is learning from it Motivating personal growth by seeking discomfort Social exploration: When people deviate from options explored by others. Surprised elaboration: When White men get longer sentences. Can’t wait or won’t wait? The two barriers to patient decisions The structure of intrinsic motivation  Get it Done: Surprising Lessons from the Science of Motivation.    Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Scientific Sense ® by Gill Eapen: Prof. Holden Thorp is Editor-in-Chief of Science family of journals. Before he was provost at Washington University where he holds appointments in both chemistry and medicine.  https://www.science.org/doi/10.1126/science.abq8460 It ain’t over ’til it’s over   The Biden administration is sheepishly waving a checkered flag on the pandemic.   h ttps://www.science.org/doi/full/10.1126/science.adf3072 Remember, do no harm? When the advocacy group America’s Frontline Doctors appeared on the steps of the United States Supreme Court in 2020, falsely stating that hydroxychloroquine was a cure for COVID-19, their pronouncement was virally shared by right-wing media and soundly debunked by medical academicians.    https://www.science.org/doi/10.1126/science.adg2577 Hard, not easy Science’s Breakthrough of the Year is the successful launch and deployment of the James Webb Space Telescope (JWST).   https://www.science.org/doi/10.1126/science.abo3934 Science needs affirmative action As science struggles to correct systemic racism in the laboratory and throughout academia in the United States, external forces press on, making it even more difficult to achieve equity on all fronts—including among scientists. The latest example is the decision by the US Supreme Court to hear cases brought against Harvard University and the University of North Carolina (UNC) at Chapel Hill challenging their right to use race as a factor in undergraduate admissions.

Scientific Sense ® by Gill Eapen: Prof. Leah Krubitzer is professor in the Department of Psychology and Center for Neuroscience at the University of California, Davis.   Her current research focuses on the impact of early experience on the cortical phenotype, and she specifically examines the effects of the sensory environment on the development of connections, functional organization and behavior and seeks to understand how culture impacts brain development.    The Combinatorial Creature: Cortical Phenotypes within and across Lifetimes.    Not all cortical expansions are the same: The coevolution of the neocortex and the dorsal thalamus in mammals  Future of the Brain: Essays by the World’s Leading Neuroscientists   Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Scientific Sense ® by Gill Eapen: Prof Trey Ideker is Professor of Medicine, Bioengineering and Computer Science at the University of California, San Diego. He directs the National Resource for Network Biology, and the Cancer Cell Map and Psychiatric Cell Map Initiatives.   A multi-scale map of cell structure fusing protein images and interactions. Nature. 2021 Nov 24. doi: 10.1038/s41586-021-04115   “We Might Not Know Half of What’s in Our Cells, New AI Technique Reveals  Interpretation of cancer mutations using a multiscale map of protein systems. Science. 2021   A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.   A protein interaction landscape of breast cancer. Science. 2021 Oct;374(6563):eabf3066  “Studies Delve Deep into the Protein Machinery of Cancer Cells.” NCI (4 Nov 2021) “From COVID to cancer, gene-mapping tool could ‘revolutionize’ treatment“. SF Chronicle (2 Oc  “Moonshot Project Aims to Understand and Beat Cancer Using Protein Maps“. Singularity Hub (5 Oct 2021)  “Looking Beyond DNA to See Cancer with New Clarity,”   Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Cancer Cell (2020), https://doi.org/10.1016/j.ccell.2020.09.014. PMID: 33096023. [PDF] [PubMed] Related Press: UCSD Health, AZoLifeSciences, Med India, Health IT Analytics and ScienceDaily.   Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome. Cell Systems. 2020 Aug 26;11(2):176-185.e6. doi: 10.1016/j.cels.2020.06.006. Epub 2020 Jul 2. PMID: 32619550 [PDF] [PubMed] *Cover Article  Related Press: Here’s a better way to convert dog years to human years, scientists say. Science Magazine (15 Nov 2019).  See also: Scientific American, BBC, NPR, Washington Post, Discover Magazine, Smithsonian, New York Post, (and more)   Identifying Epistasis in Cancer Genomes: A Delicate Affair. Cell. 2019 May 30;177(6):1375-1383. doi: 10.1016/j.cell.2019.05.005. Review. PMID: 31150618 [PDF] [PubMed]    Using deep learning to model the hierarchical structure and function of a cell.* Nat Methods. 2018 Mar 5. doi: 10.1038/nmeth.4627. PMID: 29505029 [PDF] [PubMed] [Cover Art] *Cover article   Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1