

The Last Line of Defense
Center for Strategic and International Studies
In this era of uncertainty, knowledge is power. Hosted by Dr. Seth G. Jones, The Last Line of Defense breaks down and analyzes the latest national security news. Each episode provides practical solutions to the toughest national security questions—from war and peace around the world to the role of emerging technology in defense.
Produced by Marla Hiller.
Produced by Marla Hiller.
Episodes
Mentioned books

Mar 20, 2026 • 29min
The Iran Endgame: Iran's Nuclear Program, View from Tehran & U.S. Ground Troops
Host Seth Jones sits down with Face the Nation's Margaret Brennan to break down Iran’s nuclear program and offers an overview of the domestic and international politics shaping the future of this conflict in the Middle East.

Mar 10, 2026 • 29min
Beyond the Air War: What Are the Global Risks of the Iran Conflict?
Host Seth Jones sits down with General David H. Petraeus, retired U.S. Army general and former director of the CIA, to discuss the latest developments in Iran, including ongoing military operations and the escalating challenge of countering drone and missile threats. They also explore the international response — from Gulf States and NATO allies to China, Russia, and regional proxies — and the wider implications for the Middle East.

9 snips
Mar 3, 2026 • 29min
A Widening War with Iran: What Are the U.S. Military's Next Steps
Joseph Votel, retired four-star general and former CENTCOM and Special Operations commander, offers a sharp take on U.S.-Iran military dynamics. He discusses Operation Epic Fury, rapid U.S. and Israeli air superiority, Iran’s targeting choices and regional fallout. He also covers Gulf states’ likely basing moves, limits on military influence over Iran’s politics, and strains on munitions and air defenses.

Feb 18, 2026 • 31min
Why Putin’s "Inevitable" Victory in Ukraine is a Myth
Host Seth Jones speaks with Kate Bachelder Odell of The Wall Street Journal about the state of Russia’s war in Ukraine as it nears its fifth year. They discuss recent remarks by J.D. Vance and Marco Rubio, Ukraine’s battlefield resilience, Russia’s mounting casualties, and the prospects for negotiations and a potential peace deal.

Feb 4, 2026 • 29min
Locked and Loaded: What Are U.S. Military Options for Iran?
Host Seth Jones sits down with retired Admiral Sandy Winnefeld, the ninth Vice Chairman of the Joint Chiefs of Staff, to discuss the latest developments involving Iran. They examine the U.S. military buildup near Iran and the strategic objectives of both Iran and the United States amid rising tensions.

19 snips
Jan 21, 2026 • 31min
Inside Iran's Security Apparatus: How Stable is the Regime?
Host Seth Jones speaks with Norman Roule, who served as the national intelligence manager for Iran at the Office of the Director of National Intelligence from November 2008 until September 2017. The pair discusses the ongoing protests in Iran, the regime’s response, and potential policy responses from the White House.

Jan 14, 2026 • 30min
America Under Siege: Inside China's Espionage Campaign in the United States
David R. Shedd, former Deputy Director of the Defense Intelligence Agency and author of The Great Heist, dives into the alarming rise of Chinese espionage activities in the U.S. He highlights significant cases like naval convictions and Tesla software theft, illustrating the vast implications of stolen intellectual property. Shedd also discusses the chilling Volt Typhoon initiative, which aims to infiltrate critical infrastructure, and the urgent need to protect 'crown jewel' technologies from these threats. It's a riveting look at modern espionage and national security.

9 snips
Jan 7, 2026 • 32min
Maduro is Gone. Now What in Venezuela?
Dr. Ryan Berg, Director of the Americas Program at CSIS, dives into the shifting political landscape in Venezuela following Maduro's departure. He discusses U.S. objectives including counter-narcotics and migration policies. Ryan explains the complexities of the new leadership under Delcy Rodríguez and the implications of existing power structures. The conversation explores lessons from past regime changes and the risks of internal power struggles, shedding light on the future of stability and legitimacy in Venezuela.

21 snips
Dec 17, 2025 • 32min
Which Military Shocks Defined 2025 — and What's Next in 2026?
Host Seth Jones sits down with Kari Bingen, Director of the Aerospace Security Project and a Senior Fellow in the Defense and Security Department at CSIS, and former Deputy Undersecretary of Defense for Intelligence and Security.
Together, they look back at major defense and military shocks of 2025, including Russia’s poor performance, Operation Midnight Hammer, and China’s military parade, among others. They also forecast potential wildcards for 2026, including a U.S.–China deal and land strikes in Venezuela.

10 snips
Dec 4, 2025 • 31min
Are the United States and Venezuela on the Brink of War?
Juan Cruz, a former U.S. Intelligence Community official, shares his insights on the escalating crisis in Venezuela. He discusses the complexities of U.S. objectives in removing Maduro and the challenges posed by Venezuela's role as a hub for drug trafficking. Cruz highlights the risks associated with U.S. military involvement and the asymmetrical threats from local militias and guerrillas. He also analyzes the limitations of foreign support from countries like Cuba and Russia, emphasizing the need for U.S. military readiness for potential jungle warfare.


