Science Friday

A potential CRISPR-based cure for sickle cell disease is discussed. The link between Neanderthal DNA and pain tolerance in modern humans is explored. Other topics include the moon's origin and the unique body structure of sea stars.

Dr. Noah Whiteman, evolutionary biologist, discusses the fascinating world of poisons and their evolutionary significance. Topics include toxins as defense mechanisms, toxins in coffee beans, the influence of spice obsession on history, and our connection to nature through chemicals found in plants and fungi.

The podcast discusses the importance of the placenta in pregnancy and its role in pregnancy loss. It explores a study analyzing over 1,200 placentas from miscarriages, revealing the primary causes of these losses. The episode also examines the correlation between small placentas and stillbirth, along with efforts to incorporate placenta volume measurement into prenatal care. It addresses the neglect of studying the placenta and emphasizes its significance in preventing stillbirth. Lastly, it covers the steps to take after experiencing pregnancy loss, including the examination and preservation of loss tissues.

Scientists confirm that phenylephrine, a common ingredient in cold medicines, is ineffective. The healthcare community has known this for decades. Two pharmacists collaborated to raise awareness and petition the FDA. Pharmaceutical companies are appealing the FDA's decision to remove these drugs from shelves. The podcast explores the history, studies, and potential FDA action on this issue.

Biographer Walter Isaacson discusses the origins and management style of entrepreneur Elon Musk. They explore his love for drama, risk-taking, and his employees' commitment. The podcast also highlights Musk's approach to failure, Mars colonization, and the impact and controversy surrounding him.

The podcast discusses the shortage of the RSV drug for infants due to high demand. They also talk about the spread of beech leaf disease in Massachusetts. Other interesting topics include intensification of hurricanes, genetic mutation behind 'Asian glow', discovery of mouse mummies in the Andes, menopause in chimpanzees and whales, and potential treatments for beech leaf disease.

Bestselling author Robin Wall Kimmerer discusses the role of ceremony in our lives and the importance of celebrating reciprocal relationships with the natural world. She explores the cultural and spiritual significance of Sweet Grass, the concept of reciprocity in nature, and the need for Western science to acknowledge indigenous knowledge. Kimmerer also emphasizes the role of authentic ceremony rooted in one's relationship with place and the need for collaboration between Western scientists and indigenous peoples to address ecological issues.

NASA's Psyche spacecraft is on a mission to study the metal-rich asteroid 16 Psyche, located in the asteroid belt. The spacecraft will observe the asteroid from orbit to learn about how planets form. The potential for future space mining operations is also explored. Dr. Lindy Elkins-Tanton discusses the progress and goals of the mission, including the unique properties of the asteroid. The podcast also explores the origins of Psyche and the planet formation process, as well as the formation and uniqueness of metal-rich asteroids. The chapter concludes with a discussion on the outreach efforts and longevity of the mission.

Wyoming's alpine lakes have rapidly evolving trout due to fish stocking, impacting the ecosystem. In central Colombia, the Paja Formation reveals ancient hyper-apex predators. The podcast discusses the evolution of trout in extreme environments and the rich fossil content of the Paja Formation, highlighting the influence of ancient marine reptiles on prehistoric ecosystems.

Astrobiologist Dr. Aomawa Shields shares her journey balancing acting and astronomy. She discusses the quest for life in the universe, identifying habitable planets, and the fusion of arts and sciences. The interview explores the power of stillness in generating scientific discoveries.