Fifth & Mission

"Immunocompromised" and "immunosuppressed" are familiar terms now, but they are also umbrellas for many different health situations. The CDC estimates that 7 million U.S. adults are moderately to severely immunocompromised. As the U.S. death toll surpasses 800,000 and the omicron variant rises, the most vulnerable in our communities remind us that good health is never a guarantee. Producer Téa Francesca Price shares the pandemic experiences of those with compromised immune systems.Get unlimited Chronicle access for 26 weeks for 99 cents: sfchronicle.com/pod Learn more about your ad choices. Visit megaphone.fm/adchoices

The governor is co-opting the Lone Star State's end run around the courts on abortion to target illegal homemade firearms. As reporter Dustin Gardiner tells host Demian Bulwa, Newsom sees his gambit as an attempt to use a bad tactic for something good. But the ploy faces the same problem the cops know all too well: Ghost guns are all but impossible to trace.Get unlimited Chronicle access for 26 weeks for 99 cents: sfchronicle.com/pod Learn more about your ad choices. Visit megaphone.fm/adchoices

Mayor London Breed unveiled a strategy that would significantly boost police presence in S.F.'s Tenderloin district in order to manage increased gun violence and open air drug dealing. Despite promoting alternatives to policing recently, Breed's latest plan indicates an abrupt change in tone. Chronicle reporter Trisha Thadani joins host Cecilia Lei to explain. Learn more about your ad choices. Visit megaphone.fm/adchoices

UCSF's Dr. Bob Wachter and Dr. Monica Gandhi have turned into Twitter celebrities during the coronavirus pandemic. In this Twitter Spaces conversation with host Cecilia Lei and health reporter Erin Allday, they offer their advice on the omicron variant, mask mandates and how to gather safely during the holidays. They also chat about their differing perspectives on what constitutes safe behavior.Get unlimited Chronicle access for 26 weeks for 99 cents: sfchronicle.com/pod Learn more about your ad choices. Visit megaphone.fm/adchoices

That's the question Bay Area communities are answering as money is distributed from the bipartisan infrastructure bill and possibly President Biden's Build Back Better bill. Political correspondent Tal Kopan joins host Demian Bulwa to talk about the big local projects that stand to benefit, from improving train lines and the Golden Gate Bridge to fighting drought and wildfires.Get unlimited Chronicle access for 26 weeks for 99 cents: sfchronicle.com/pod Learn more about your ad choices. Visit megaphone.fm/adchoices

It's a holiday tradition that brings the flavor of Victorian London to the Cow Palace. But some participants are boycotting over what they say is the parent company's failure to make the fair safe and inclusive for all. LaToya Tooles and Arielle Kesweder join host Cecilia Lei to talk about the problems haunting the event.Get unlimited Chronicle access for 26 weeks for 99 cents: sfchronicle.com/pod Learn more about your ad choices. Visit megaphone.fm/adchoices

What you need to know about the emergence of the omicron variant of COVID-19 in Northern California. Chronicle health reporter Erin Allday talks to host Demian Bulwa about how contagious and dangerous it is, and how well vaccinations and boosters protect against it. Allday also discusses the rising number of cases in the Bay Area heading into the holidays, and explains the link between the world's vaccine effort and the fight to better treat HIV.Get unlimited Chronicle access for 26 weeks for 99 cents: sfchronicle.com/pod Learn more about your ad choices. Visit megaphone.fm/adchoices

The small and mighty East Bay city is on track to exceed its regional housing development goals, unlike other cities in the Bay Area. Emeryville has long had a reputation of welcoming development of all kinds, including affordable housing. Chronicle reporter J.K. Dineen joins host Cecilia Lei to discuss why the city is uniquely positioned to do so, and what other cities can learn from its approach.Get unlimited Chronicle access for 26 weeks for 99 cents: sfchronicle.com/pod Learn more about your ad choices. Visit megaphone.fm/adchoices

They've been a lifeline to restaurants, who were thrilled when the city made them permanent. But a slew of new rules might mean many will have to go. Zack Schwab, who owns the Pacific Heights bar the Snug, and Chronicle food reporter Janelle Bitker join Cecilia Lei to talk about it.Get unlimited Chronicle access for 26 weeks for 99 cents: sfchronicle.com/pod Learn more about your ad choices. Visit megaphone.fm/adchoices

Fifth & Mission Host Demian Bulwa speaks with columnist Heather Knight and photographer Gabrielle Lurie about their story following a mother's desperate search to find her daughter in San Francisco, and get her clean from fentanyl. Laurie Steves quit her job, left her home in a Seattle suburb and moved to San Francisco with the desperate hope that she would not lose another child to drug addiction, but she had no idea how challenging that process would be.   Learn more about your ad choices. Visit megaphone.fm/adchoices