

Serious Inquiries Only
seriouspod.com
Join Thomas for some critical thinking on questions of science, philosophy, skepticism and politics. These serious topics are discussed with some serious guests, but in an entertaining and engaging way! This is not your typical interview podcast; it's a friendly dialogue, conducted thoughtfully and with plenty of humor. It's Serious Inquiries Only; but like, not boring or anything.
Episodes
Mentioned books

Mar 26, 2026 • 44min
SIO507: Shirley You're Joking, Minnesota Fraud Man!
It's part 2 of the Minnesota fraud stuff. We get a little more Nick Shirley, dumbest person ever to testify in congress. And then I debunk the main claims against Gov. Walz and AG Ellison. Did Walz un-stop the payments to Feed Our Future? Did Ellison meet with, and then get campaign donations from the fraudsters?

Mar 24, 2026 • 48min
SIO506: Minnesota Fraud and the Death of Information
So now that we've covered a real hearing with brave whistleblowers that got NO attention, it's time to look at what happens over on the other side of the aisle.

Mar 15, 2026 • 1h 19min
SIO505: The ICE Whistleblower Hearing Was Astonishing. It Needs More Attention.
Last month, there was a devastating hearing featuring a victim of ICE, an ICE whistleblower, and a previous DHS attorney. It revealed what, in any other time, would have been a massive scandal likely resulting in multiple firings. But we live in the bad times, which means this hearing took place in a maintenance shed barely on Congressional property during lunchtime put on by a ragtag team of the few remaining people who give a shit about constitutional rights. I take you through the hearing, and then next episode we're going to compare this to the Minnesota fraud hearings, of which the MAGA controlled congress has had... 3? 4? There is a marked difference in the seriousness of the people involved.

Mar 15, 2026 • 1h 2min
SIO504: The Other Kind of Nut Allergy. Well, Both Kinds, I Guess?
Part 2! Even more fun Quibbies. Allergies Bansal, A.S., Chee, R., Nagendran, V., Warner, A., & Hayman, G. (2007). Dangerous liaison: Sexually transmitted allergic reaction to Brazil nuts. Journal of Investigational Allergology and Clinical Immunology, 17, 189-191. Testosterone University of Zurich (2009, December 9). Testosterone does not induce aggression, study shows. ScienceDaily. Eisenegger, C., Naef, M., Snozzi, R., Heinrichs, M., & Fehr, E. (2010). Prejudice and truth about the effect of testosterone on human bargaining behavior. Nature, 463, 356-359. ADHD and TikTok Verma, S. & Sinha, S.K. (2024). How evidence-based is the "hashtag ADHD test" (#adhdtest). A cross-sectional content analysis of TikTok videos on attention-deficit/hyperactivity disorder (ADHD) screening. Australian Psychiatry, 0, 1-7. Are you an expert in something and want to be on the show? Apply here!

Feb 26, 2026 • 51min
SIO503: Viral Post Claims Texas Has More Democrats Than Republicans. Is That True?
It's Quibi Time (tm) with Jenessa! (Don't worry, I'll explain...) It's 2 debunks for the price of 1, or actually 5 debunks for the price of 2, because this is a two-parter! Here are the first two: AI girlfriend Caramela, S. (2025, January 31). Most Men Would Marry Their AI Girlfriend if it were Legal. Vice. Fiorillo, C. & Bartlett, S. (2025, January 28). AI girlfriends could be a thing of the future as men admit they would marry robot lovers. The Mirror. Koetsier, J. (2025, April 29). 80% Of Gen Zers Would Marry An AI: Study. Forbes. Mashable. (2025, May 22). Majority of Gen Z would marry an AI, survey says. Yahoo!Life. (2025, May 11). GenZ Believes They Could Marry AI, Replace Human Connections: Report. NDTV World. Ulanoff, L. (2025, May 22). Would you marry an AI? A recent survey says most Gen Z-ers would - here's why that's a ridiculous idea. Techradar. Texas voter registration (2025, August 7). Texas. Independent Voter Project. (Thomas saw this viral Reddit post about it) Texas by the Numbers. L2. January 2025 Voter Registration Figures. Texas Secretary of State. Turnout and Voter Registration Figures (1970 - current). Texas Secretary of State. Are you an expert in something and want to be on the show? Apply here!

Jan 27, 2026 • 2h 27min
This Is The Dark Place. Why Aren't We Acting Like It?
I had a lot I needed to say about the ICE murders of Rene Good and Alex Pretti. And about the fascists who lie to our faces and know we can't do anything about it. And the concentration camps we already have. I did video because there was so much visual element to this, so watching would be best.

Jan 7, 2026 • 51min
SIO501: What Pluribus Gets Right about Neuroscience
Subject of much sci-fi media and philosophy discussions, the "hive mind" is also a key element of Vince Gilligan's (Breaking Bad, Better Call Saul) new show, Pluribus. Dr. Jenessa Seymour joins the pod to walk us through examples that we have studied of hive mind behavior (in the insect world), and why we can reasonably assert that you could not maintain your individuality if our brains directly communicated with each other (in the human world). Wolman, D. (2012). A tale of two halves. Nature, 483, 260-263. Split brain patient video demonstration Wittlinger, M., Wehner, R., & Wolf, H. (2006). The ant odometer: Stepping on stilts and stumps. Science, 312, 1965-1967. Penick, C.A. & Smith, A.A. (2015). The true odor of the odorous house ant. American Entomologist, 61, 85-87. Are you an expert in something and want to be on the show? Apply here! Please support the show on patreon! You get ad free episodes, early episodes, and other bonus content!

Jan 1, 2026 • 1h 13min
SIO500: A New Study Suggests Brain Imaging Might Have Significant Flaws
Brain pics, or they didn't happen? There's a recent study that demonstrates that some brain region activity might interact differently with oxygen than previously assumed. This could upend significant neuroscience research spanning decades. Thankfully SIO has Dr. Jenessa Seymour to come in and break it all down for us! We start with a primer on the science of neuroimaging tools and the images they produce. How in the WORLD can we get a picture of a brain while a person is still alive? What are the things we need to know when evaluating scholarly articles or popular media coverage about the brain that uses these brain "scans" in discussing their results? And what do we need to see next to support the findings of this study that could have incredible ramifications across our understanding of the brain? Epp, S.M., Castrillón, G., Yuan, B. et al. BOLD signal changes can oppose oxygen metabolism across the human cortex. Nat Neurosci (2025). Example structural MRI (sMRI) of a human brain Güttler, F.V., Heinrich, A., Rump, J., de Bucourt, M., Schnackenburg, B., … Teichgräber, U.K. (2012). Magnetic resonance imaging of the active second stage of labour: Proof of principle. European Radiology, 22, 2020–2026 Diffusion Tensor Imaging (DTI) example image Example functional MRI (fMRI) Example fMRI with a more-appropriately blurry sMRI underneath After Warping Options, Configurable Pipeline for the Analysis of Connectomes (0, 4, and 8mm filter images) Jenessa's Brain: Jenessa's brain sMRI Are you an expert in something and want to be on the show? Apply here! Please support the show on patreon! You get ad free episodes, early episodes, and other bonus content!

Dec 2, 2025 • 1h 10min
SIO499: Trump Is Weaponizing Government Against Political Enemies. Nick Fish, President of American Atheists, on How to Be Prepared
In late September, shortly after declaring antifa a "domestic terrorist", Trump issued a memorandum directing the IRS to investigate tax-exempt organizations that could be "directly or indirectly financing political violence or domestic terrorism" and nonprofit organizations reasonably felt concerned of being targeted. A couple of weeks later, Lydia and Thomas ran into Nick Fish, President of the American Atheists, at California Freethought Day and asked how he and the organization were holding up in light of everything. We're pleased to have Nick on to discuss what nonprofit organizations can do to protect themselves, as well as the people who have supported their mission and the communities they serve, when it is feeling less and less paranoid that the federal government might be coming for you. How can organizations fortify themselves through governing documents and organizational structure to donor databases and retention policies when the President of the United States could very well declare your nonprofit a supporter of domestic terrorism? Countering Domestic Terrorism and Organized Political Violence (NSPM-7) (9/25/2025) Support American Atheists!

Nov 26, 2025 • 1h 9min
SIO498: The Science of Hallucinations, Ear-worms, and Phantom Limbs
Dr. Jenessa Seymour is on to teach us more about the brain! What do hallucinations, ear-worms, and phantom limbs have in common? And is "hallucinating" really a good term for what AI does when it makes something up?


