ICU Ed and Todd-Cast

Eddie and Todd
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Feb 25, 2025 • 57min

TRAUMOX2, SAHARA, and mailbag

Send us a Text Message (please include your email so we can respond!)Episode 59! We finish our CCR down under coverage with TRAUMOX2 or "Early Restrictive vs Liberal Oxygen for Trauma Patients" published in JAMA by Arleth et al and then switch to SAHARA or "Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage" by English et al published in NEJM. We then frustrate Todd with questions from our mailbag, a good episode!TRAUMOX2 (pubmed): https://pubmed.ncbi.nlm.nih.gov/39657224/TRAUMOX2 (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2827980SAHARA (pubmed): https://pubmed.ncbi.nlm.nih.gov/39655786/SAHARA (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2410962If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music! 
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Feb 11, 2025 • 57min

Old/New: FLORALI and RENOVATE

Send us a Text Message (please include your email so we can respond!)Episode 58! We talk about non-invasive oxygen support and RENOVATE or "High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure" published in JAMA December 2024 and presented at the CCR Down Under Conference. We supplement this by first talking about FLORALI or "High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure" published in NEJM May 2015RENOVATE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39657981/RENOVATE (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2828065FLORALI (pubmed): https://pubmed.ncbi.nlm.nih.gov/25981908/FLORALI (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa1503326If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music! 
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Jan 28, 2025 • 1h 6min

CCR Down Under: SCREEN with Adam Wright

Send us a Text Message (please include your email so we can respond!)Episode 57! We were excited to have on this episode Dr. Adam Wright who is a PhD in Bioinformatics to discuss SCREEN or "Electronic Sepsis Screening Among Patients Admitted to Hospital Wards: A Stepped-Wedge Cluster Randomized Trial" published by Arabi et al in JAMA 2024 and presented at the CCR Down Under Conference. A long episode but a lot of good discussionSCREEN (pubmed): https://pubmed.ncbi.nlm.nih.gov/39658862/SCREEN (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2828069If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music! 
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Jan 14, 2025 • 46min

CCR Down Under: ADAPT-Sepsis

Send us a Text Message (please include your email so we can respond!)Episode 56! In this episode we spend a few minutes talking about making decisions on ECMO initiation but spend most of the episode talking about ADAPT-Sepsis or "Biomarker-Guided Antibiotic Duration for Hospitalized PatientsWith Suspected Sepsis" published by Dark et al in JAMA 2024 and presented at the CCR Down Under Conference.ADAPT-Sepsis (pubmed): https://pubmed.ncbi.nlm.nih.gov/39652885/ADAPT-Sepsis (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2828036If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music! 
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Dec 31, 2024 • 60min

2024 Year in Review and CCR Down Under

Send us a Text Message (please include your email so we can respond!)Episode 55 and Happy New Year! In this episode we talk broad strokes about the CCR Down Under Conference and the trials that were presented, then Todd and Eddie go over a bunch of articles from the year 2024 that they didn't have time to go over or want to re-emphasize for whatever reason. Big show and we hope you enjoy!TIGHT K: https://pubmed.ncbi.nlm.nih.gov/39215972/PROPHY VAP: https://pubmed.ncbi.nlm.nih.gov/38262428/REVISE: https://pubmed.ncbi.nlm.nih.gov/38875111/Point (withdrawal of ECMO): https://pubmed.ncbi.nlm.nih.gov/39663030/Counterpoint: https://pubmed.ncbi.nlm.nih.gov/39663031/DanGer SHOCK: https://pubmed.ncbi.nlm.nih.gov/38587239/Intubation in physiologic difficult airway guidelines: https://pubmed.ncbi.nlm.nih.gov/39162823/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music! 
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Dec 17, 2024 • 52min

New/Old: BALANCE and iDIAPASON

Send us a Text Message (please include your email so we can respond!)Episode 54! In this episode we talk about antibiotic duration in bacteremia (BALANCE) and also antibiotic duration in Pseudomonas Ventilator associated pneumonia (iDIAPASON). BALANCE (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa2404991BALANCE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39565030/iDIAPASON (ICM): https://link.springer.com/article/10.1007/s00134-022-06690-5iDIAPASON (pubmed): https://pubmed.ncbi.nlm.nih.gov/35552788/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music! 
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Dec 3, 2024 • 34min

New/New-ish: IVIO and PARAMEDIC-3

Send us a Text Message (please include your email so we can respond!)Episode 53! In this episode we talk about access in patients with out of hospital cardiac arrest. Both articles are similar so we talk in depth about IVIO and then bringing PARAMEDIC-3 to round out our discussion. A good acronym discussion too, don't miss it!IVIO (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2407616IVIO (pubmed): https://pubmed.ncbi.nlm.nih.gov/39480221/PARAMEDIC-3 (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa2407780PARAMEDIC-3 (pubmed): https://pubmed.ncbi.nlm.nih.gov/39480216/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music! 
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Nov 19, 2024 • 41min

New/New: INTREPID and PROLABI

Discover the intriguing connection between fever and neurological injuries, and the challenges of managing temperature in stroke patients. Enjoy a light-hearted yet insightful examination of the INTREPID trial on fever prevention. The episode delves into patient comfort in ICUs and how it impacts recovery outcomes. Tune in for a critical look at the PROLABI trial, discussing ventilation strategies for severe brain injuries. Balancing humor with serious medical insights, the hosts dissect essential clinical trial designs and their implications.
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Nov 5, 2024 • 23min

LIVE @ CC Bootcamp 2024: NONSEDA

Send us a Text Message (please include your email so we can respond!)We are (were) LIVE at ACNP Critical Care Bootcamp 2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about the NONSEDA trial or "Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients" by Olsen et al published in the New England Journal of Medicine February 2020NONSEDA (pubmed): https://pubmed.ncbi.nlm.nih.gov/32068366/NONSEDA (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa1906759If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music! 
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Oct 22, 2024 • 56min

FAST and IV Fluid Shortage

Send us a Text Message (please include your email so we can respond!)Episode 50! In this episode we talk about SBT frequency and "Frequency of Screening and Spontaneous Breathing Trial Techniques" by Burns et al from JAMA 2024 that was released with the ESICM conference. In our second segment, instead of another trial we talk a little bit about the IV fluid shortage happening in the United States.FAST (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2824928FAST (pubmed): https://pubmed.ncbi.nlm.nih.gov/39382222/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music! 

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