Modern Healthspan

In this episode Dr Furman discusses what are the chief components of that make up the iAge clock and how they differ from the markers of acute inflammation. In particular CXCL9 is the main element of the iAge clock while classic marker of inflammation such as CRP, IL-6, TNF-alpha do not appear at all. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. Dr Furman's paper on iAGE An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging https://www.nature.com/articles/s43587-021-00082-y https://www.biorxiv.org/content/10.1101/840363v1 Prof David Furman’s Lab in Buck Institute Website https://www.buckinstitute.org/lab/furman-lab/ Stanford 1000 Immunomes Project (KIP) Website: https://med.stanford.edu/1000immunomes If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/ $5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. Dr Furman's paper on iAGE An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging https://www.nature.com/articles/s43587-021-00082-y https://www.biorxiv.org/content/10.1101/840363v1 Prof David Furman’s Lab in Buck Institute Website https://www.buckinstitute.org/lab/furman-lab/ Stanford 1000 Immunomes Project (KIP) Website: https://med.stanford.edu/1000immunomes If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/ $5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

In this episode Dr Furman discusses chronic inflammation and how it differs from acute inflammation. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. Dr Furman's paper on iAGE An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging https://www.nature.com/articles/s43587-021-00082-y https://www.biorxiv.org/content/10.1101/840363v1 Prof David Furman’s Lab in Buck Institute Website https://www.buckinstitute.org/lab/furman-lab/ Stanford 1000 Immunomes Project (KIP) Website: https://med.stanford.edu/1000immunomes If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/ $5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

In this episode Dr Kaufmann talks about her personal protocol, how many supplements she takes (52) and some of the more advanced therapies that she uses, such as exosomes. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechanisms of aging on a cellular level and the best supplements to slow down its progress. Links for Dr Kaufmann The Kaufmann Protocol website https://kaufmannprotocol.com/ The Kaufmann Protocol: https://amzn.to/3rhBAq7

In this episode Dr Kaufmann talks about supplements and eye drops for aging eyes, including carnosine eye drops which may be able to reverse long sight. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechanisms of aging on a cellular level and the best supplements to slow down its progress. Links for Dr Kaufmann The Kaufmann Protocol website https://kaufmannprotocol.com/ The Kaufmann Protocol: https://amzn.to/3rhBAq7

In this episode Dr Kaufmann talks about supplements, that can be used to address loss of hair and loss of hair colour, including Ecklonia Cava a supplement from Japanese seaweed. We also cover sarcopenia where the supplements are leucine, collagen, resveratrol or pterostilbene and a source of nicotinamide, such as NMN or NR. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechanisms of aging on a cellular level and the best supplements to slow down its progress. Links for Dr Kaufmann The Kaufmann Protocol website https://kaufmannprotocol.com/ The Kaufmann Protocol: https://amzn.to/3rhBAq7

In this episode Dr Kaufmann talks about the her list of required supplements for those who are over 40. This has the 5 from her original book, Pterostilbene, Astaxanthin, Nicotinamide, Carnosine, Curcumin. To which she has now added Quercetin, Lactoferrin and Spermidine. We also discuss some of them in more detail, touching on rapamycin and delivery systems such as liposomes and nano micelles. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechanisms of aging on a cellular level and the best supplements to slow down its progress. Links for Dr Kaufmann The Kaufmann Protocol website https://kaufmannprotocol.com/ The Kaufmann Protocol: https://amzn.to/3rhBAq7

In this episode Dr Kaufmann talks about her system for rating molecules for their efficacy based on the scientific evidence available. She also discusses her new book which extends from her first book and adds more supplements to the list. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechanisms of aging on a cellular level and the best supplements to slow down its progress. Links for Dr Kaufmann The Kaufmann Protocol website https://kaufmannprotocol.com/ The Kaufmann Protocol: https://amzn.to/3rhBAq7

In this video Dr Kaufmann provides an introduction of what led her to start studying aging and the process that she used to develop her 7 tenets. She then goes through the tenets explaining what each one is. She uses the analogy of a factory to show how the pieces fit together. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechanisms of aging on a cellular level and the best supplements to slow down its progress. Links for Dr Kaufmann The Kaufmann Protocol website https://kaufmannprotocol.com/ The Kaufmann Protocol: https://amzn.to/3rhBAq7

In this episode Dr Longo talks the diet and exercise for longevity and whether it is necessary to exercise when fasting. He also shares his own longevity protocol Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology. Professor Longo has thirty years of experience in the field of longevity and healthy nutrition. His most recent studies focus on the use of Fast-Mimicking diet interventions to activate stem cell- based regeneration to promote longevity. In 2018, TIME Magazine named Professor Longo as one of the 50 most influential people in health care for his research on fasting-mimicking diets as a way to improve health and prevent disease. Dr Longo's book on Amazon The Longevity Diet: Slow Aging, Fight Disease, Optimize Weight https://amzn.to/30PmY6j Professor Longo's Facebook page. https://www.facebook.com/profvalterlongo/ Create Cures Foundation https://www.createcures.org/ If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/