Neurology® Podcast

Zika virus interviews

1) Predictive value of ABCD2 and ABCD3-1 scores in TIA and minor stroke in the Stroke Unit Setting2) e-Pearl topic: Alternating hemiplegia of childhood3) Topic of the month: Neurology Today story about his book review on: "The Laws of Medicine: Field Notes from an Uncertain Science."This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Anna Ranta interviews Dr. Michael Knoflach about his paper on the predictive value of ABCD2 and ABCD3-1 scores in transient ischemic attack and minor stroke in the Stroke Unit Setting. Dr. Steve O'Donnell is reading our e-Pearl of the week about alternating hemiplegia of childhood. Dr. Ted Burns interviews Jose Merino about a Neurology Today story about his book review on: "The Laws of Medicine: Field Notes from an Uncertain Science."DISCLOSURES: Dr. Ranta receives research support from the New Zealand Health Research Council.Dr. O'Donnell serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Merino serves as US Clinical Research Editor for the BMJ; serves as Co-editor, blogging stroke (A Stroke journal blog); receives stroke outcomes adjudicator for the WHI study (NIH-funded); and DSMB of a PCORI-funded trial to evaluate depression in caregivers of patients with Alzheimer disease.

1) Anti-LGI1-associated cognitive impairment: Presentation and long-term outcome2) e-Pearl topic: Moyamoya disease and syndrome3) Topic of the month: Neurology Today story on a published paper titled: Intensive Blood-Pressure Lowering in Patients with Acute Cerebral HemorrhageThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Lara Marcuse interviews Drs. Francesc Graus and Josep Dalmau about their paper on the presentation and long-term outcome of anti-LGI1-associated cognitive impairment. Dr. Steve O'Donnell is reading our e-Pearl of the week about Moyamoya disease and syndrome. Dr. Javier Provencio interviews Dr. Adnan Qureshi about a Neurology Today story on his published paper titled: Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.DISCLOSURES: Dr. Graus serves as an editorial board member of Lancet; receives license fee Payments from Euroimmun for the use of IgLON5 as a diagnostic test; holds a patent for the use of IgLON5 as a diagnostic test.Dr. Dalmau serves as Editor of Neurology®: Neuroimmunology & Neuroinfammation; serves as an Editorial board member of Neurology® and UpToDate; receives royalties from patents for the use of Ma2 and NMDAR as autoantibody tests; is a consult for Advance Medical, receives research support from Euroimmun and the NIH; receives revenue from Euroimmun for the following tests: NMDA receptor autoantibody test, GABA(B)R autoantibody test, GABA(A)R autoantibody test, DPPX autoantibody test and Iglon5 autoantibody test.Dr. O'Donnell serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Provencio serves as an editorial board member of Journal of Neuroimmunology, serves on the scientific advisory board for Minnetronix, INC. (travel related expenses) and Advanced Circulatory, Inc (travel related expenses); received honoraria from Bard, Inc.; receives royalties from the publication of the book "Family Guide to Surviving the ICU"; receives research support from Bard Inc., Cryothermics INC. and the NIH.

1) Neurology® Neuroimmunology & Neuroinflammation: Next-generation sequencing in neuropathological diagnosis of infections of the nervous system2) e-Pearl topic: GABAb receptor encephalitis3) Topic of the month: Neurology Today story about the global burden of strokeThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Heather Harle interviews Dr. Carlo Pardo about his Neurology® Neuroimmunology & Neuroinflammation paper on next-generation sequencing in neuropathological diagnosis of infections of the nervous system. Dr. Steve O'Donnell is reading our e-Pearl of the week about GABAb receptor encephalitis. Dr. Andy Southerland interviews Dr. Vladimir Hachinski about a Neurology Today story on the topic of the global burden of stroke.DISCLOSURES: Dr. Pardo receive research support from the Bart McLean Fund for Neuroimmunology Research-Project Restore and the NIH.Dr. O'Donnell serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Southerland serves as Podcast Deputy Editor for Neurology; receives research support from the American Heart Association-American Stroke Association National Clinical Research Program, American Academy of Neurology, American Board of Psychiatry and Neurology, Health Resources Services Administration and the NIH; has a provisional patent application titled: "Method, system and computer readable medium for improving treatment times for rapid evaluation of acute stroke via mobile telemedicine;" and gave legal expert review.NO CME WILL BE OFFERED THIS WEEK.

1) Impaired self-agency in functional movement disorders2) What's Trending: Interview with James Sejvar about possible links between Zika virus, microcephaly, and Guillain–Barre syndrome3) Topic of the month: Neurology Today story about where advances are revolutionizing stroke treatmentThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Michelle Fullard interviews Dr. Carine Maurer about her paper on impaired self-agency in functional movement disorders Dr. Andy Southerland is interviewing Dr. James Sejvar for our "What's Trending" feature of the week on the topic of possible links between Zika virus, microcephaly, and Guillain–Barre syndrome. Dr. Andy Southerland interviews Dr. Ralph Sacco about a Neurology Today story on the topic of where advances are revolutionizing stroke treatment.DISCLOSURES: Dr. Maurer receives research support from the NINDS Intramural Program.Dr. Southerland serves as Podcast Deputy Editor for Neurology; receives research support from the American Heart Association-American Stroke Association National Clinical Research Program, American Academy of Neurology, American Board of Psychiatry and Neurology, Health Resources Services Administration and the NIH; has a provisional patent application titled: "Method, system and computer readable medium for improving treatment times for rapid evaluation of acute stroke via mobile telemedicine;" and gave legal expert review.Dr. Sacco serves as an editorial board member of Stroke and Neuroepidemiology; serves on the scientific advisory board for DSMB for SOCRATES Trial through UCSF(indirect sponsor Astra Zeneca) and EUCLID trial through Duke Clinical Research Institute (indirect sponsor Astra Zeneca); receives research support from Boehringer Ingelheim, Evelyn McKnight Brain Institute, American Heart Association Burgher Foundation and the NIH.

1) The clinical spectrum of Caspr2-antibody associated disease2) What's Trending: Interview with Lenore Launer about how hostile attitudes and effortful coping in young adulthood can predict cognition in later life 3) Topic of the month: Neurology Today story about five mentally stimulating activities associated with a lower risk for mild cognitive impairmentThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeremy Lanford interviews Dr. Maarten Titulaer about his paper on the clinical spectrum of Caspr2-antibody associated disease. Dr. Ted Burns is interviewing Dr. Lenore Launer for our "What's Trending" feature of the week about her paper on how hostile attitudes and effortful coping in young adulthood can predict cognition in later life. Dr. Ted Burns interviews Drs. Janina Krell-Roesch and Gregg Day about a Neurology Today story on the topic of five mentally stimulating activities associated with a lower risk for mild cognitive impairment.DISCLOSURES: Dr. Titulaer serves on the scientific advisory board for MedImmune; serves as an editorial board member for Neurology®: Neuroimmunology & Neuroinflammation; received funding for travel from Sun Pharma; receives research support from Netherlands Organization for Scientific Research, Dutch Epilepsy Foundations and ErasmusMC fellowship.Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Launer receives research support from the National Institute on Aging Intramural Research Program.Dr. Day received funding for travel from Pfizer, Canada for Future Leader in Dementia award; receives Research support from Avid Pharmaceuticals, American Brain Foundation, Clinical Research Training Fellowship, Eugene M Johnson Jr, Weston Brain Institute Postdoctoral Fellowship; and holds stock options in ANI Pharmaceuticals (2014-2015).

1) International consensus guidance for management of myasthenia gravis2) e-Pearl topic: Progressive multifocal leukoencephalopathy3) Topic of the month: Neurology Year in Review Plenary Session at the AAN meeting on the topic of headacheThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Donald Sanders about the executive summary on the international consensus guidance for management of myasthenia gravis. Dr. Ilena George is reading our e-Pearl of the week about progressive multifocal leukoencephalopathy. Dr. Tesha Monteith interviews Dr. Richard Lipton about his Neurology Year in Review Plenary Session at the AAN meeting on the topic of headache.DISCLOSURES: Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Sanders receives royalties from the publication of the book: Single Fiber EMG; serves on the medical advisory board for Accordant Health Services; is a consultant for ArGen-X, Jacobus Pharmaceutical Co., Inc, Modus Outcomes, Momenta Pharmaceuticals, Inc. and UCB Celltech.Dr. George serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Monteith serves as an editorial advisory board member for Neurology Now and receives research support from the NIH.Dr. Lipton receives royalties for books published from Oxford University Press and Baxter Publishing; Receives honoraria for serving on the scientific advisory board for Alder, Allergan, Inc., American Headache Society, Autonomic Technologies, Avanir Pharmaceuticals, Boehringer Ingelheim, Boston Scientific, Bristol-Myers Squibb, CoLucid, Dr. Reddys, Electrocore, Eli Lilly and Company, eNeura Therapeutics, Informa, Merck Serono, Novartis, Pfizer Inc, Teva Pharmaceutical Industries Ltd., Vedanta; is a consultant for Alder, Allergan, Inc., American Headache Society, Autonomic Technologies, Avanir Pharmaceuticals, Boehringer Ingelheim, Boston Scientific, Bristol-Myers Squibb, CoLucid, Dr. Reddys, Electrocore, Eli Lilly and Company, eNeura Therapeutics, Informa, Merck Serono, Novartis, Pfizer Inc, Teva Pharmaceutical Industries Ltd., Vedanta; holds stock options in eNeura Pharma; receives research support from Bristol-Myers Squibb, Vedanta Research Migraine epidemiology and Progression. Boston Scientific Occipital Nerve Stimulation in Migraine, ElectroCore Vagal Nerve Stimulation for Migraine and Cluster, Novartis Sleep and Migraine, Allergan Botox in Migraine, Allergan Chronic Migraine Epidemiology and Outcome Study, S & L Marx Foundation Alzheimer's Research and the NIH.

1) Zika virus-associated Guillain-Barre Syndrome Variant in Haiti2 e-Pearl topic: Juvenile Huntington Disease3) Topic of the month: Clinical Trials Plenary Session at the AAN meeting about 5-HT6 antagonist as adjunctive therapy to cholinesterase inhibitors in patients with mild-to-moderate Alzheimer diseaseThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Stephen Donahue interviews Dr. Aaron Berkowitz about his paper on Zika virus-associated Guillain-Barre syndrome variant in Haiti. Dr. Ilena George is reading our e-Pearl of the week about juvenile Huntington disease. Dr. Alberto Espay interviews Dr. Alireza Atri about his Clinical Trials Plenary Session at the AAN meeting about 5-HT6 antagonist as adjunctive therapy to cholinesterase inhibitors in patients with mild-to-moderate Alzheimer disease.DISCLOSURES: Dr. Berkowitz receives royalties from the publication of the book: Clinical Pathophysiology Made Ridiculously Simple and the book: The Improvising Mind; received funding for travel from Stevens Institute of Technology; received speaker honorarium from Audio Digest; and received honorarium for recorded CME lecture.Dr. George serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Espay serves as Associate Editor for the Journal of Clinical Movement Disorders; serves as an editorial board member of Parkinsonism and Related Disorders and The European Neurological Journal; serves on the scientific advisory board for Solvay Pharmaceuticals, Inc. (now Abbvie), Chelsea Therapeutics International, Ltd., Teva Pharmaceutical Industries Ltd., Impax, Merz Pharmaceuticals, Inc., Pfizer Inc, Solstice Neurosciences, Eli Lilly and Company, ACADIA Pharmaceuticals, Inc. and USWorldMeds; is a consultant for Chelsea Therapeutics International, Ltd., Solvay Pharmaceuticals, Inc. (now Abbvie), ACADIA Pharmaceuticals, Inc., Cynapsus and Lundbeck, Inc; receives royalties for publications of books from Lippincott, Williams & Wilkins and Cambridge University Press; serves on the speakers' bureau of UCB, Teva Pharmaceutical Industries Ltd., American Academy of Neurology and Movement Disorders Society; receives research support from the CleveMed/Great Lake Neurotechnilogies, Michael J. Fox Foundation and the NIH.

Dr. Ted Burns interviews Dr. Clinton Wright about his paper on leisure time physical activity and how it is associated with cognitive decline. Dr. Alberto Espay interviews Dr. Jeremy Schmahmann about his Frontiers in Neuroscience Plenary Session at the AAN meeting about the implications for neurology and psychiatry in the treatment of cerebellar cognitive affective syndrome.

Migraine updates and discussion on the topics of migraine genetics, science behind lifestyle factors, science behind lifestyle factors and clinical trials - July 2016