This Week in Startups

Jason Calacanis
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4 snips
Mar 25, 2026 • 1h 15min

$2.5B Chip Heist, The Future of American AI, and Purpose-Built Robots | This Week in AI Ep 6

This Week in AI sneak peak! If you enjoy the episode find us on Spotify, Apple podcasts and YouTube by looking up "This Week in AI" or by going to thisweekinai.aiThis week Jason sat down with Jake Loosararian and Chris Lattner on Episode 6 of This Week in AI. Jake is the CEO and co-founder of Gecko Robotics, a company deploying purpose-built robots and AI for mission-critical infrastructure inspection across energy, defense, and manufacturing. Chris is the CEO and co-founder of Modular, building a universal software layer that lets developers run AI models across Nvidia, AMD, and Apple silicon without being locked into any single hardware vendor.We explore the GPU shortage, why China's chip smuggling reveals the stakes of the AI cold war, how purpose-built robotics are beating humanoids on ROI, the case for American reindustrialization, and why the next decade could be the best ever for private equity in capital-intensive industries.Purpose-Built Robots vs. Humanoids: Jake has been building mission-critical robots for 13 years. He explains why general-purpose humanoids still have too little ROI for industrial use, and why specialized robots that find and fix problems are winning in the field.The GPU Shortage Is Real: Chris breaks down why you can't just go buy 100 Blackwell chips today, why Nvidia's Cuda creates massive lock-in, and how Modular is building a unified software layer across all major chip architectures.Google TPUs Are the Sleeper: Chris ranks Google as the number one threat to Nvidia's dominance, ahead of Amazon's Trainium and AMD.China's Chip Smuggling & the AI Cold War: A Supermicro co-founder allegedly smuggled $2.5B in Nvidia chips to China using fake serial numbers and a hairdryer. The Best Decade for Private Equity: Jake makes the case that capital-intensive, commoditized infrastructure assets: waste-to-energy, water treatment, old power plants will all generate incredible returns.Self-Driving State of Play: Chris, a former Tesla Autopilot lead, gives his read on Waymo's lead, Tesla's small Austin pilot, and why the real signal is when Tesla starts filing for fully autonomous permits in California.Learn more about Gecko Robotics: https://www.geckorobotics.comLearn more about Modular: https://www.modular.com/This Week In AI is made possible by:*PayPalOpen* - One Platform for all Business: paypalopen.com*Timestamps:*00:00 Welcome & intro to Jake Lu (Gecko Robotics) and Chris Lattner (Modular)01:34 Gecko's 13-year journey & the Cantilever platform05:15 Chris Lattner on Modular: replacing Cuda & unifying AI hardware11:10 Nvidia lock-in, AMD's Rock & why the software stack is broken19:49 The GPU shortage: how real is it?22:13 Who challenges Nvidia? Google TPUs, Amazon Trainium & AMD ranked28:17 China chip smuggling: $2.5B in Nvidia GPUs & the AI cold war37:43 Self-driving update: Waymo, Tesla's Austin pilot & Chris's Tesla history42:20 Figure's humanoid package sorting — real or demo magic?43:47 The best decade for private equity in capital-intensive assets51:04 Reindustrialization, the trades boom & making manufacturing cool58:39 Building tech companies outside Silicon Valley1:06:46 Breaking news: Brett Adcock launches Hark from Figure1:10:15 Closing thoughts: grit over hype, customers over valuationsSubscribe to This Week in AI on Apple: https://thisweekinai.ai/spotifySubscribe to This Week in AI on Spotify: https://thisweekinai.ai/appleThanks for watching!🤖 If you want to stay ahead of the curve on all things AI, make sure to join our community across all platforms:📩 Get the Weekly Newsletter: https://thisweekinai.ai/📺 Subscribe on YouTube: https://www.youtube.com/@ThisWeekinAIPodcast📸 Instagram: https://www.instagram.com/thisweekinaipodcast📱 TikTok: https://www.tiktok.com/@thisweekinaipodcast✖️X: https://x.com/ThisWeeknAIFollow Jason:X: https://twitter.com/JasonFollow Oliver:https://x.com/oliverkorzen
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Mar 24, 2026 • 1h 27min

Compliance Startup Scandal... Is Delve Guilty? | E2266

This Week In Startups is made possible by:Northwest Registered Agent - https://northwestregisteredagent.com/twistLinkedIn Jobs - https://linkedIn.com/twistSentry - https://sentry.io/twistPlaud - http://Plaud.ai/twistRo.co - http://Ro.co/TwistToday’s show:Hustle Fund general partner Elizabeth Yin joined Jason and Alex to discuss how rapid advances in AI have changed the venture capital game, and how the same AI updates are changing how founders build. Founders may need less capital than before, which could reduce their reliance on venture dollars over time.Ceel founder Ryan Mahdavi joined next to help Jason and Alex dig into the Delve story. Well-funded Delve was publicly criticized for allegedly overselling their compliance tool’s capabilities and not being honest with customers. Delve has responded to the allegations, though Mahdavi said that he had his doubts about the competing startup even before the news story broke.Next, TWiST invited Brick founder Seg Sheng on to explain his startup’s plan to use a combination of physical hardware and artificial intelligence to help buildings and data centers reduce their energy bills. Given how much juice the AI era demands, Brick could be onto something big.And to close out the show, Gavin Zaentz and Pranav Ramesh from LeadPoet (Bittensor Subnet 71) to show off their technology (the pair put in motion a lead hunt for Brick while on-air). It’s a packed show with something for everyone. Let’s go!Timestamps:0:00 Intro1:18 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!3:45 Elizabeth Yin from Hustle Fund on how AI tools have changed her workflow9:21 How founders use AI to learn how to suck less10:34 Sentry - New users can get $240 in free credits when they go to https://sentry.io/twist and use the code TWIST13:17 Ryan Mahdavi from Ceel joins to explain the Delve SOC 2 scandal18:39 Is Silicon Valley's "bend the rules" culture at fault?20:38 Red and pink flags, and how investors can spot potential fraud21:41 LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at https://LinkedIn.com/twist23:45 How to not do securities fraud: a simple guide26:50 Ryan asks: How did the company get through diligence?31:03 Northwest Registered Agent — Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://northwestregisteredagent.com/twist32:25 Were there early warning signs about issues with Delve?33:26 On Delve's use of tactical donuts36:55 What about the Delve board? If there is one?45:24 Seb Sheng stops by to tell us about how Brick Data saves companies massively on energy costs49:38 Who are Brick's customers and how much are they paying?54:16 Lightning Round: A quick history of Brick56:02 Why Jason is so bullish on $TAO56:45 Ro.co: Ro's insurance checker will let you know if your coverage includes GLP-1s for FREE. Go to https://Ro.co/Twist for your free insurance check.1:06:35 How do LeadPoet's "miners" track down the best leads?1:13:09 How Bittensor subnets map to traditional startup forms1:17:15 How can agents build up authority if they can't get hired for their first job?1:21:03 Jason: "I think the game of Bitcoin has ended…"1:23:22 Why Jason likes to place a bet, then learn1:24:16 The inherent risks in crypto investmentSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out Jason’s suite of newsletters: https://substack.com/@calacanis
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Mar 20, 2026 • 1h 39min

The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265

This Week In Startups is made possible by:Northwest Registered Agent - https://www.northwestregisteredagent.com/twistCircle - https://circle.so/twistNetsuite - https://www.netsuite.com/twistToday’s show:Zipline founder Keller Cliffton started his company with a simple premise: build automated logistics that serve everyone equally. The only problem? It was literally illegal in the US.In this live recording from LaunchFest in San Francisco, Keller shares how Zipline went from a 20-person team working on a cow farm in Rwanda to operating the largest commercial autonomous system on Earth. They now complete 130 million autonomous miles with zero accidents, while reducing maternal mortality by 51% in the regions they serve.PLUS we’ve got Rahul Vohra from Superhuman taking us through his entire founder journey, and discussing with Jason why “difficult” founders are often the smartest investments.Timestamps:0:00 Intro1:16 Keller Cliffton starts off the show3:05 Starting Zipline in Africa8:40 The magic of sky maps13:55 Building the drone was just the beginning15:11 Making a huge difference in maternal mortality23:48 The threats of Little Evil Jimmy and dogs29:37 The shift from Rwanda to Dallas31:14 Netsuite - Get the free business guide Demystifying AI at https://www.netsuite.com/twist32:28 The moral clarity of the mission41:17 The challenge of staying focused46:43 Rahul Vohra of Superhuman joins Jason49:40 Building Rapportive in Cambridge51:48 Scaling to millions of users via APIs1:11:46 How getting acquired made Rahul fearless1:12:31 The boldness of taking on Gmail1:22:12 Making everyone pay for the product1:31:24 Inside the Grammarly-Superhuman dealSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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Mar 18, 2026 • 50min

How Robinhood became a $68B company w/ Vlad Tenev

This Week In Startups is made possible by:Deel - https://deel.com/twistLinkedIn Jobs - https://LinkedIn.com/twist.Iru - https://iru.com/twistToday’s show:We’ve got a treat for you today on TWiST! Jason is live from LAUNCH Fest in San Francisco, where he’s joined by Robinhood founder Vlad Tenev.The era of AI is here. Robinhood found success in the midst of the last great technological shift. What lessons did Vlad take from this, and how can founders apply these to this next transformative period? What elements are the same and what elements have changed?Let’s get inside the mind of one of the greatest founders of the last decade!Timestamps:0:00 Why Jason runs events like LAUNCH Fest.3:25 The early days of Jason and Vlad.5:54 Why getting users before monetizing creates a bigger business.9:49 Deel - Founders ship faster on Deel. Set up payroll for any country in minutes and get back to building. Visit https://deel.com/twist to learn more.11:03 Finding ways to launch a product multiple times.13:49 How Robinhood identified its initial customers.20:09 LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at https://LinkedIn.com/twist.21:04 Robinhood's "give to get" and waitlist mechanics explained.25:07 Navigating mistakes that feel existential (they're not!)27:36 Leaning into negative press.30:30 Iru - Iru unifies identity, endpoint security, and compliance into one platform. TWiST listeners get 20% off when they book a demo at https://iru.com/twist32:13 Tackling competition in the AI era.37:20 How Vlad hires and develops talent.42:16 What is good design in an era of vibe coded slop?46:46 Vlad's top lessons from the last 10 years.Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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Mar 16, 2026 • 1h 14min

Are Brain-Computer Interfaces Actually Ready for Humans?

This Week In Startups is made possible by:Caldera + Lab - https://CalderaLab.com/TWISTNorthwest Registered Agent - https://northwestregisteredagent.com/twistLemon - https://Lemon.io/twistToday’s show:Computers that read your mind? Jets that are all wings? Continuously tracking your body’s vital signs to live longer? We’ve got all that and more on the show today.First, we sat down with the CEO of Paradromics, Matt Angle, to dig into the progress that his brain-computer interface startup has made. Yes, there are more companies working on BCIs than just Neuralink. Paradromics, in particular, is looking for early clinical trial subjects as it works to bring its technology out of the lab and into the market.If you ever wanted to know more about how BCIs work and how long it will be until we can all benefit from the tech, this is the interview for you.Next, we got JetZero CEO Tom O'Leary on the phone to tell us all about his startup’s jet. No, it’s not competing with Boom, a startup that wants to build a supersonic passenger airliner. Instead, JetZero is building jets that are mostly wing, allowing them to fly with far greater fuel efficiency. Best of all? The future JetZero planes can fit right into normal airports.Finally, we chatted with Nutrisense CEO Dan Zavorotny. While keeping tabs on your glucose levels may not be the sexiest topic in the world, the data that continuous monitoring can bring is incredibly valuable health information. Mix that signal with coaching, and Nutrisense reckons its combination of software, data, and dieticians can really improve health outcomes for its customers.If you needed a break from pure-play AI news, TWiST has you covered!Timestamps:0:00 Introduction1:47 Paradromics3:26 How do BCIs read your mind?9:58 Lemon - Get 15% off your first 4 weeks of developer time at Lemon.io/twist19:54 Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at northwestregisteredagent.com/twist27:24 JetZero29:07 The advantages of more wing30:13 Caldera Lab - Whether you're starting fresh or upgrading your routine, Caldera Lab makes skincare simple and effective. Head to CalderaLab.com/TWIST and use TWIST at checkout for 20% off your first order.55:30 NutrisenseSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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Mar 14, 2026 • 1h 30min

One Genius Rule That Made This Coffee Brand Famous | EP 2262

Legendary British ad man Rory Sutherland invented a fake business on a podcast, a coffee shop appealing to the busy commuter called “Flat White or F**k Off.”But it’s one thing to have a post go big on TikTok or Instagram… but to turn that viral moment into an actual COMPANY is a very different challenge.On TWiST, Jason and Lon chat with Charlie Hurst, Tom Noble, and Will Sudlow, founders of the online brand “Flat White or F**k Off,” about how they took a funny little slogan and turned it into a string of popular social media accounts, a line of merch, a pop-up café, and let’s face it, an entire lifestyle.PLUS we’ve got Mog and Dubs from Subnet 75 — Hippius! Hear how they’re using the blockchain for decentralized storage, and providing server space much cheaper than their famous hyperscaler rivals.This Week In Startups is made possible by:Plaud - https://Plaud.ai/twistLinkedIn Jobs - https://LinkedIn.com/twist.Wispr Flow - https://wisprflow.ai/twistNorthwest Registered Agent  - https://www.northwestregisteredagent.com/twistTimestamps:00:00:00 Intro00:01:28 Plaud - If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!00:03:22 What is "decentralized cloud storage"?00:05:42 How Hippius came together00:09:57 LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at https://LinkedIn.com/twist.00:11:38 Incentivizing miners00:14:25 How many people are contributing?00:18:42 But where does the value accrue?00:20:18 Wispr Flow - Stop typing. Dictate with Wispr Flow and send clean, final-draft writing in seconds. Visit https://wisprflow.ai/twist to get started for free today.00:29:55 Northwest Registered Agent. Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://www.northwestregisteredagent.com/twist00:35:53 The best places to eat in Dubai00:38:06 The inspo behind "Flat White or F Off"00:42:16 From social media to IRL business00:53:06 The secrets of experiential marketing00:57:28 Hospitality's "Rule of 3s"00:59:33 Inside the Flat White London pop-up01:13:11 Lon and Jason's Oscar picks01:26:06 Lon went "Inside the Manosphere"Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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Mar 11, 2026 • 1h 9min

The Global Expansion of Self-Driving Vehicles

This Week In Startups is made possible by:Circle - http://circle.so/twistSentry - http://Sentry.ioDeel - http://deel.com/twistPlaud - http://Plaud.ai/twistToday’s show:It’s self-driving time! We’re going deep on one of the most exciting spaces developing in the world, autonomous vehicles! We’ve got 3 experts on the show to talk to us enlighten us, Ben Seidl of Autolane, Ming Maa of Moove, and Nathan Parker of EdgeCase.What’s going on in the world of self-driving? How has the reliability of autonomous vehicles improved? What challenges are we still facing in the industry? Will the US reign victorious, or is China sneaking up? Let’s find out on TWiST!Timestamps:00:00 intro02:21 Uber teams up with Zoox! 03:02 Does EdgeCase work with Zoox? 03:03 Operational design domains 06:47 The challenges of bringing self-driving to new environments. 00:10:53 Circle: The easiest way to build a home for your community, events, and courses — all under your own brand. TWiST listeners get $1,000 off the Circle Plus Plan by going to http://circle.so/twist. 00:13:26 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at Plaud.ai/twist and use code TWIST for 10% off! 00:17:19 How has reliability of autonomous cars improved? 00:19:18 How Ben Seidl came up with the idea for Autolane! 00:21:08 Sentry: New users can get $240 in free credits when they go to https://sentry.io/twist and use the code TWIST 00:27:47 How Moove helps autonmous vehicles go to market! 00:30:49 Deel: Founders ship faster on Deel. Set up payroll for any country in minutes and get back to building. Visit https://deel.com/twist to learn more. 00:33:28 The logisitcs of managing fleets. 00:37:08 Why is it called Autolane and not multi-modal lane? 00:40:50 Does EdgeCase work with smaller self-driving vehicles as well? 00:41:52 How autonomous systems will interact with one-another! 00:43:14 Why AV’s should not talk to other AV’s on the road 00:45:07 The state of the self-driving market 00:49:12 Why Tesla isn’t involving themselves in California 00:50:34 Why the US is leading the way with regulatory clarity in autonomous vehicles 01:02:51 Ben Seidl says federal regulation is a necessity 01:05:20 What is holding back self-driving growth in the US? 01:06:26 What companies make the most money in self driving Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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Mar 10, 2026 • 1h 1min

How agents will change banking forever | E2260

Eugene Stuckless, founder of Eir / Air Inc., builds AI-native automation and testing tools. He demos AirTests using agents to run and improve website and workflow tests. The conversation covers agent-driven self-training, limiting blast radius for safety, and how agent loops change testing and banking automation.
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4 snips
Mar 6, 2026 • 1h 8min

Wisdom of the $TAO: the future is decentralized AI

This Week In Startups is made possible by:Every Banking - https://Every.iohttps://Lemon.io - Lemon.io/twistWispr Flow - https://wisprflow.ai/twistPlaud - https://plaud.ai/twistRo.co - https://Ro.co/TwistToday’s show:*Sure, we all love open source models, but what about completely decentralized AI? Rather than leaving the big decision-making in the hands of a few elite CEOs, shouldn’t users have a say — and potentially even a stake — in how this incredible technology develops?On TWiST, we welcome Ala Shaabana of Crucible Labs, one of the co-founders of Bittensor. It’s an open-source protocol powering a blockchain-based machine learning network. What does that mean? Users mine a crypto token — $TAO — but rather than using up their compute on solving extremely long equations, they devote it to actually powering a range of innovative AI apps (aka subnets).Plus we’ve got Mark Jeffrey, co-founder of the Bittensor Fund Stillcore Capital, to show us some of his favorite subnet projects, and walk us through how he trained his AI agent to mine crpyto.All that AND two amazing new OpenClaw demos.Mark Jeffrey: https://x.com/markjeffreyStillcore Capital: https://stillcorecapital.com/Ala Shaabana (Crucible Labs): https://x.com/CrucibleLabsMichael Ryaboy (Setup Claw): https://setupclaw.com/Pete and Maddie Reese (Bizzby AI): https://bizzby.ai/Timestamps:00:00 Intro01:28 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!04:11 The booming intersection of crypto, and AI agents05:49 Mark Jeffrey joins the show!06:13 Bittensor explained — how TAO subsidizes AI products07:37 Mark’s top Bittensor projects00:10:40 https://Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit https://every.io.00:12:20 How subnet tokens work00:17:34 How the Crucible Labs wallet simplifies subnet token allocation00:19:33 https://Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist00:22:42 The importance of private inference and encrypted AI prompts00:29:36 Wispr Flow: Stop typing. Dictate with Wispr Flow and send clean, final-draft writing in seconds. Visit https://wisprflow.ai/twist to get started for free today.00:33:07 How AI is restoring old movies and media!00:40:57 SetUpClaw’s “set it and forget it” AI agents00:45:50 https://Ro.co: Ro’s insurance checker will let you know if your coverage includes GLP-1s for FREE. Go to https://Ro.co/Twist for your free insurance check.00:54:35 “Off-duty” with Lon and JasonSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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Mar 5, 2026 • 1h 21min

Is Anthropic Making the Biggest Mistake in AI History | E2258

This Week In Startups is made possible by:Plaud - Plaud.ai/twistLinkedIn Jobs - https://LinkedIn.com/twist.Deel - https://deel.com/twistIru - https://iru.com/twist!Today’s show:It’s a packed TWiST Today! WITH US, we’ve got Erik Voorhees of VeniceAI and Logan Allin of Fin Capital on to talk agents, crypto, and… you guessed it, OPENCLAW!Where does agentic AI meet the financial system? How will agents transact? And what does privacy look like in a world with omnipresent AI?Stick around for some demos! We’ve got George Pickett to demo OpenClaw studio and David Kaufman to show us what he’s building at Siteline!Timestamps:00:04:31 What was Logan’s original thesis in Circle?10:08 LinkedIn Jobs - Thanks to our partners at @LinkedIn! Post your job for free at https://⁠linkedIn.com/twist⁠ then promote it to get access to LinkedIn Jobs’ new AI assistant.00:11:52 Logans thoughts on Open vs. Closed Source00:15:33 How to maintain privacy in AI20:02 Deel - Founders ship faster on Deel. Set up payroll for any country in minutes and get back to building. Visit https://⁠deel.com/twist⁠ to learn more.00:23:29 Why LAUNCH’s token usage is trending higher than payroll!00:25:05 How Fin capital uses personality types and AI to assess investments00:29:45 Why Erik thinks Anthropic’s defiance of the federal gov. is bravery!32:10 Iru - Iru unifies identity, endpoint security, and compliance into one platform. TWiST listeners get 20% off when they book a demo at https://⁠iru.com⁠/twist!00:42:23 How Siteline is helping understand companies and their agent traffic.00:57:15 OpenClaw Studio makes OpenClaw as user friendly as possible.01:10:09 The layers and layers of Microstrategy’s business model.01:11:44 Which AI tools are the most indispensable?01:12:25 How Jason uses the Grok button on threadsSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com

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