Last Week in Medicine

Stephen Jenkins, MD, Austin Rupp, MD
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Mar 18, 2020 • 30min

COVID-19 Update, Gabapentin for Alcohol Use Disorder, Apixaban versus Rivaroxaban for Atrial Fibrillation

Seems like a lot has happened in just one week!  The whole world is different. Today we talk about some of the most recent articles published about the ongoing COVID-19 pandemic.  We also discuss whether gabapentin can be used to treat people with alcohol use disorder, and whether apixaban is better than rivaroxaban for preventing strokes in people with atrial fibrillation. Incubation Period for COVID-19Risk Factors for Mortality in COVID-19Risk Factors for ARDS and Death in COVID-19Caring for Critically Ill Patients with COVID-19Detection of COVID-19 in ChildrenGabapentin for Alcohol Use Disorder Apixaban versus Rivaroxaban for Atrial FibrillationMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
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Mar 10, 2020 • 25min

Long Acting Injectable Therapy for HIV and Pregnenolone for Chronic Low Back Pain

Austin finally returns to the podcast with harrowing tales of almost being eaten by a wolf.  Today we discuss a new NEJM paper about long acting injectable therapy for HIV and a new JAMA paper about pregnenolone, a neurosteroid that may help treat the scourge of primary care: chronic low back pain. Long Acting Cabotegravir and Rilpivirine for HIV-1Pregnenolone vs Placebo for Chronic Low Back Pain in Veterans Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
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Mar 4, 2020 • 33min

COVID-19, PPI Use and MDRO Colonization, Hospitalist Care of ED Boarders

Today we had Dr. Dani Babbel back on the show to talk about the latest COVID-19 updates, whether gastric acid suppression increases your risk of MDRO colonization, and how to improve care to patients boarding in the emergency department.  Check it out! Characteristics of Covid-19 in ChinaCovid-19 Report from CDC of China Gastric Acid Suppression and MDRO Colonization Hospitalist Care of ED Boarders and Length of Stay Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
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Feb 25, 2020 • 32min

Empirical Anti-MRSA vs Standard Antibiotic Therapy in Pneumonia, High Consulting Hospitalists, Medicare for All

Today we had the pleasure of talking to Dr. Barbara Jones, first author on a new paper in JAMA IM about the outcomes in veterans treated with empirical anti-MRSA therapy vs standard therapy.  She gives us a master class in propensity weighted analysis and instrumental variable analysis.  We also look at whether outcomes are different in patients who are cared for by hospitalists who call more consults than their colleagues, and how much money we could save with a single payer system in the United States. Empirical Anti-MRSA vs Standard Antibiotic Therapy in Pneumonia High Consulting Hospitalists and Patient OutcomesMedicare for All in the USMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
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Feb 19, 2020 • 31min

Plasma Exchange and Glucocorticoids for ANCA-Vasculitis and Dexamethasone for ARDS, aka the PLEX and DEX episode

Today we have the venerable EBM guru Dr. Brian Locke on the show to talk PLEX and DEX.  Does plasma exchange for ANCA-vasculitis really work?  Do steroids make any difference in patients with ARDS?  Also, have you ever wondered which Hogwarts house your medical specialty belongs to? Plasma Exchange and Glucocorticoids for ANCA-Vasculitis Dexamethasone for Acute Respiratory Distress SyndromeThe Sorting Hat of Medicine: Why Hufflepuffs Wear Stethoscopes and Slytherins Carry ScalpelsMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
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Feb 11, 2020 • 29min

Aspirin for VTE Prophylaxis after THA or TKA, Fluid Management for Sepsis in Patients with ESRD, Cirrhosis and CHF

Today we are joined by the man, the myth, and the legend, Dr. Stacy Johnson, to talk about a new meta-analysis of using aspirin for DVT prophylaxis after a total hip or knee replacement.  We also review a new retrospective cohort study from Cleveland Clinic on whether it's safe to give the recommended 30 ml/kg fluid bolus to patients with sepsis who also have CHF, cirrhosis or ESRD.  Check it out! Aspirin for VTE Prophylaxis after THA or TKA Fluid Management for Sepsis in Patients with ESRD, Cirrhosis and CHF Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
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Feb 4, 2020 • 29min

CT Screening for Lung Cancer, Conservative vs Interventional Treatment for Spontaneous Pneumothorax

Today we are joined by the very smart Dr. Jason Carr, a pulmonary/critical care fellow, to talk about two big papers from the wonderful world of lungs.  Does CT screening for lung cancer save lives?  Do you have to put a chest tube in every patient with a spontaneous pneumothorax?  Check it out! CT Screening for Lung Cancer, AKA NELSON Conservative vs Interventional Treatment for Spontaneous PneumothoraxMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
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Jan 28, 2020 • 28min

Novel Coronavirus, High Sensitivity Troponins, Hydroxyethyl Starch for Abdominal Surgery and Testosterone Therapy in Men

It's our tenth episode!  Thanks for getting us this far.  Today we discuss the new coronavirus outbreak, what to do with high sensitivity troponins, whether hydroxyethyl starch should be used in abdominal surgery (spoiler alert: it shouldn't) and the appropriate use of testosterone therapy.Novel Coronavirus in China High Sensitivity Troponins and the Fourth Universal Definition of MIHydroxyethyl Starch versus Saline in Major Abdominal SurgeryEfficacy and Safety of Testosterone Treatment in Men Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
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Jan 22, 2020 • 31min

Factor XIa Inhibition for VTE Prophylaxis, Physician Time Using EHR in Outpatient Encounters, Vitamin C and Thiamine for Septic Shock

Today we are joined by the wonderful Dr. Emily Signor to talk about new therapeutic approaches to DVT prophylaxis, how much time physicians spend using the EHR in clinic, and whether that Vitamin C cocktail works for septic shock.  Check it out! Effect of Osocimab in Preventing VTE in Patients Undergoing TKA Physician Time Spent Using the EHR During Outpatient EncountersVitamin C, Thiamine and Hydrocortisone for Septic ShockMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
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Jan 14, 2020 • 32min

Health Care Hotspotting, Valve Replacement in Asymptomatic Very Severe Aortic Stenosis, Free Medications and Treatment Adherence

Today we try something a little different -- three co-hosts!  Dr. Dani Babbel joins Jenkins and Rupp for some lively discussion about hotspotting, very severe aortic stenosis and whether adherence improves when medications are free.  Check it out! Health Care HotspottingEarly Surgery for Asymptomatic Aortic Stenosis Effect on Treatment Adherence of Distributing Essential Medicines at No ChargeMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R

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