

Shadow World
BBC Radio 4
In Shadow World: Impulsive, Noel Titheradge uncovers the devastating side effects of a class of prescription drugs which can cause hypersexuality and compulsive gambling.
Gripping stories from the Shadows - BBC investigations from across the UK.
Gripping stories from the Shadows - BBC investigations from across the UK.
Episodes
Mentioned books

Feb 13, 2026 • 14min
Impulsive: 10. Reflections
Valerie Voon, neuropsychiatrist and researcher who advises on impulse control disorders, explains why dopamine agonist behavioral side effects are stigmatized. She discusses how to reframe these changes as medical side effects. The conversation covers lack of patient insight, shifting identities and the heavy personal and financial costs people can face.

Feb 13, 2026 • 14min
Impulsive: 9. Blame Game
A journalist probes links between Parkinson’s medications and severe impulsive behaviours. The story follows one solicitor’s collapse after treatment and the family fallout, including a suicide. Investigations reveal hundreds of similar reports, legal actions, industry responses and regulator debates. The episode examines drug warnings, prescribing trends and calls for clearer information.

Feb 13, 2026 • 15min
Impulsive: 8. Collateral
A respected solicitor is arrested after hundreds of thousands go missing from elderly clients. Family members describe shocking behavioural changes, compulsive spending and collections tied to Parkinson’s medication. The story traces emotional fallout, victims’ suffering and questions about who should be held accountable for drug-related harms.

Feb 13, 2026 • 14min
Impulsive: 7. Missed connections
A reporter probes cases where dopamine-affecting drugs appear linked to compulsive behaviours like gambling and hypersexuality. People discover worrying side effects only after harm has happened. Families describe chaotic, life-changing crises sparked by medication leaflets. The investigation examines failures in communication and why warnings may not have reached those at risk.

Feb 13, 2026 • 15min
Impulsive: 6. Chasing Losses
A woman’s first scratchcard win spirals into daily gambling and online betting. A prescribed medication with dopamine effects triggers compulsive eating, hypersexuality and risky travel behavior. Family history of mental illness and workplace stress set the scene for a psychotic breakdown. Repeated attempts to stop fail as losses mount and a friend spots a possible drug link.

Feb 13, 2026 • 14min
Impulsive: 5. Restless
A woman struggles with severe restless leg sensations and insomnia after a diagnosis and treatment with a Parkinson’s drug. The medication’s dose keeps rising while her behaviour shifts into compulsive, risky sexual activity and secret online encounters. The story explores worsening symptoms despite treatment, a drug-related impulse control disorder, and the fallout for relationships and accountability.

Feb 13, 2026 • 15min
Impulsive: 4. Big Pharma, Big Secret
A reporter chases whistleblowers and leaked internal documents from a major pharma firm. Stories of patients developing extreme impulse control problems after taking dopamine agonist drugs are recounted. The investigation reveals a years‑long gap between company knowledge and public warnings. Legal battles and personal fallout from undisclosed side effects are explored.

Feb 13, 2026 • 14min
Impulsive: 3. Dopamine Hits
Valerie Voon, a neuropsychiatry professor at Cambridge who studies dopamine and impulse-control, explains how dopamine shapes reward and risk. She breaks down reward prediction and learning. Short, clear takes on why certain drugs can drive risky, compulsive behaviors.

Feb 13, 2026 • 15min
Impulsive: 2. Wonder drugs
A man's Parkinson’s diagnosis leads to compulsive late-night webcam spending after starting dopamine agonist medication. The story traces escalating secret behavior, mounting debt and the emotional cycle of highs and guilt. Medical experts explain how newer Parkinson’s drugs work and why warnings about impulsive side effects were missed.

Feb 13, 2026 • 14min
Impulsive: 1. Warning Signs
Freddie, son of Bill who developed Parkinson’s, shares a concise family perspective on his father’s post-medication changes. He describes renewed zest for life followed by startling out-of-character behaviours. The conversation covers sudden hypersexuality, impulsive travel and spending, risky decisions and the broader investigation into dopamine-related drug effects.


