Asimov Press

Asimov Press
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Feb 22, 2026 • 20min

The Origins of Agar

They trace agar from a 17th century kitchen discovery to a wartime strategic resource for vaccines and penicillin. They recount Fanny Hesse's pivotal suggestion and Koch's plating breakthrough. They explore why agar outperforms other gels, its complex seaweed origins, global supply pressures, recent toxic-batch disruptions, and efforts to find replacements.
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Feb 19, 2026 • 11min

Baseline Drift

[Fiction] A eulogy to the reference human. By Eliomer H. Kaas.Read all our work, for free, at press.asimov.com.
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Feb 16, 2026 • 33min

Scent, In Silico

Computational mapping of smell and why odor resists simple digital encoding. Practical uses from leak detection to diagnostics and sustainable fragrance design. Traces olfaction from bacterial chemo-sensing to vertebrate evolution and neural memory links. Machine learning, graph neural nets, and the principal odor map reveal new scent spaces. Synthetic molecules and cultural tensions around natural ingredients are explored.
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Feb 12, 2026 • 9min

Making the Vortex Mixer

A deep dive into the 1959 invention that changed lab work, tracing how a simple motorized rubber cup created the orbital vortex used in mixing tubes. The Kraft brothers’ background and rapid prototyping are highlighted. Listeners hear how the device solved contamination problems, passed clinical tests, spawned patents and businesses, and evolved into the ubiquitous Vortex Genie and modern variants.
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Feb 8, 2026 • 21min

A Brief History of Xenopus

A whirlwind tour of how Xenopus frogs shaped fertility tests, embryology, and cloning. Short stories about frog-based assays, large eggs used as experimental tools, and landmark organizer grafts. Tales of genomic puzzles, cell-free egg extracts that unlocked cell biology, and a shift to a diploid species for modern genetics.
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Feb 1, 2026 • 40min

What It's Like To Be A Worm

A deep dive into how scientists probe sentience in tiny creatures and machines. They trace historical ideas from Darwin to modern connectomics. The talk tackles controversies over worm and insect awareness, the limits of behavioral evidence, and why neural wiring and valence matter. It highlights technical hurdles, competing brain theories, and the high moral stakes of deciding who can feel.
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11 snips
Jan 26, 2026 • 33min

Building Brains on a Computer

A roadmap for building human-scale brain emulations, covering breakthroughs that shifted feasibility like expansion microscopy and protein barcodes. Discussion of core needs: recording neural activity, reconstructing wiring, and digitally modeling neurons. Practical timelines, cost estimates, and scaling bottlenecks such as proofreading, compute, and data collection are explored.
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Jan 18, 2026 • 37min

Mystery of the Head Activator

Dive into the captivating world of developmental biology as a controversial discovery unravels. A researcher’s promising claim about the head activator ignites acclaim but quickly turns sour with failed replication attempts. Uncover the intricate biology of hydras and the ensuing battle over scientific recognition. Personal dynamics, gender issues, and fierce disputes color the story, ultimately leading to a major scientific shift towards the Wnt pathway. The unresolved puzzle leaves lingering questions and reflections on legacy.
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10 snips
Jan 15, 2026 • 16min

Solving the Electroporation Bottleneck

Discover how Cultivarium is tackling the challenges of engineering non-model organisms. Niko McCarty delves into the limitations of E. coli dominance in research and the reasons scientists avoid less-studied microbes. Learn the ins and outs of electroporation, a groundbreaking technique that uses electrical pulses for DNA entry. The conversation highlights Cultivarium's innovative robotics that optimize transformation experiments and the significant role of non-model organisms in scientific breakthroughs like PCR and CRISPR.
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Jan 12, 2026 • 43min

Inventing the Methods Section

What the evolution of scientific methods says about their future. By Andrew Hunt.Read all our work for free at press.asimov.com.

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