

Brain Ponderings podcast with Dr. Mark Mattson
Mark Mattson
Conversations with neuroscientists, neurologists, evolutionary biologists, anthropologists, computer scientists, and others that ponder the brain.
Here are a few of the questions that BRAIN PONDERINGS will tackle:
How have brains evolved to enable success in diverse environments?
How does the brain develop in the womb and in early life?
What are the mechanisms responsible for learning and memory, language, and emotions?
How does the brain respond to life's challenges?
In what ways does the brain influence the body and vice-versa?
What is known about the causes of psychiatric, neurodegenerative, and other brain disorders?
What new technologies are being developed to treat neurological disorders?
How do naturally occurring and man-made chemicals affect the brain?
How can gene therapy, cell regeneration, and brain stimulation be used for brain disorders?
What are the boundaries between ethical and unethical neuroscience research?
Here are a few of the questions that BRAIN PONDERINGS will tackle:
How have brains evolved to enable success in diverse environments?
How does the brain develop in the womb and in early life?
What are the mechanisms responsible for learning and memory, language, and emotions?
How does the brain respond to life's challenges?
In what ways does the brain influence the body and vice-versa?
What is known about the causes of psychiatric, neurodegenerative, and other brain disorders?
What new technologies are being developed to treat neurological disorders?
How do naturally occurring and man-made chemicals affect the brain?
How can gene therapy, cell regeneration, and brain stimulation be used for brain disorders?
What are the boundaries between ethical and unethical neuroscience research?
Episodes
Mentioned books

Jun 1, 2022 • 56min
Pondering Clever Hyenas with Kay Holekamp
In this episode I talk with evolutionary and behavioral biologist Kay Holekamp talks about her fascinating research on spotted hyenas that has shed light on the evolution of intelligence. By studying the behaviors of hyena social groups in Kenya, Professor Holekamp and her students have revealed the remarkable cognitive capabilities of these animals. Their work has provided valuable insight into how the brain evolved complex social skills to enable flourishing in harsh environments. For further details and pictures of the hyenas visit: https://www.youtube.com/watch?v=ZZDs7n9j-KE Her publications can be found at: https://pubmed.ncbi.nlm.nih.gov/?term=kay+holekamp&sort=date&size=200

Jun 1, 2022 • 1h 8min
Pondering Good and Bad Stress with Robert Sapolsky
Professor Robert Sapolsky - Stanford University - talks about his research into how chronic psychosocial stress adversely affects the brain in ways that predispose it to anxiety disorders, depression, and Alzheimer's disease. His studies of baboons in Kenya and of rodents in the laboratory established a major role for the adrenal hormone cortisol in promoting the atrophy and death of neurons in the brain.

Jun 1, 2022 • 46min
Pondering Feathered Apes with Nicky Clayton
I talk with Professor Nicola (Nicky) Clayton at Cambridge University about her experiments which have established the remarkable cognitive capabilities of corvids which are birds in the crow family. By studying their food caching (hiding) behaviors Nicky and her students have shown that corvids can read the minds of other birds, and they can remember details of past events and plan for the future. Moreover, corvids seem to have a working knowledge of the laws of physics and they can craft and use tools to solve problems. Nicky also talks about her research on the development of cognition in children, and her efforts to foster collaborations between scientists and people in the performing arts.

Mar 5, 2022 • 1h 46min
Pondering the Social Brain with Robin Dunbar
Professor Robin Dunbar of Oxford University has studied the social networks of apes and humans for more than 50 years. He is the author of the book "Friends". In this podcast he describes how the superior computational power of the human brain evolved to enable enduring lifelong social interactions that enhance security, reduce discord, and facilitate information exchange within and across generations. Dunbar has shown that there is an optimal group size for all social species; that number in humans is 150. In this podcast he talks about the neuronal networks in the brain that evolved to maintain and enhance harmony within social groups. Dunbar describes how language, music, and laughter enhance sociality. He also discusses how very large social groups of a size well beyond the evolutionarily ancient optimal size (for example, religious and political groups) enhance social cohesion within the group while simultaneously fostering antagonism towards individuals not in the group.

Feb 15, 2022 • 1h 24min
Brain Ponderings 1, Joseph LeDoux, The Evolution of Emotions
In this episode Professor Joseph LeDoux, author of the books 'The Emotional Brain, 'Anxious', and 'The Deep History of Ourselves' talks about how emotions evolved as adaptations that enable survival and reproductive success in harsh environments. His findings have provide evidence that emotional experiences are inherently cognitive in nature which has important implications for helping people with an anxiety disorder or depression.


