Neurology Minute

American Academy of Neurology
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Nov 12, 2025 • 3min

Prodromal Phase of Migraine - Part 2

In the second part of this two-part series, Dr. Bradley Ong explains the four clinical phases of a typical migraine attack. Show citation: Lipton RB, Stokes J, Evans CJ, et al. Characterizing the patient experience during the prodrome phase of migraine: A qualitative study of symptoms and their timing. Headache. 2025;65(8):1355-1368. doi:10.1111/head.15024
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Nov 11, 2025 • 3min

Prodromal Phase of Migraine - Part 1

In part one of this two-part series, Dr. Bradley Ong discusses the prodrome phase of migraine and how it represents the earliest stage of the attack. Show citation: Lipton RB, Stokes J, Evans CJ, et al. Characterizing the patient experience during the prodrome phase of migraine: A qualitative study of symptoms and their timing. Headache. 2025;65(8):1355-1368. doi:10.1111/head.15024
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Nov 10, 2025 • 2min

Sex-Related Gap in the Use of Disease-Modifying Therapies in Multiple Sclerosis - Part 2

In part two of this series, Dr. Stacey Clardy and Dr. Sandra Vukusic discuss gender disparities in the treatment of multiple sclerosis. Show citation: Gavoille A, Leray E, Marignier R, et al. Sex-Related Gap in the Use of Disease-Modifying Therapies in Multiple Sclerosis. Neurology. 105(4) e213907. doi:10.1212/WNL.0000000000213907
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Nov 7, 2025 • 4min

Sex-Related Gap in the Use of Disease-Modifying Therapies in Multiple Sclerosis - Part 1

In part one of this two-part series, Dr. Stacey Clardy and Dr. Sandra Vukusic discuss what disease-modifying therapies can be safely continued and strategically timed when pregnancy is anticipated. Show citation: Gavoille A, Leray E, Marignier R, et al. Sex-Related Gap in the Use of Disease-Modifying Therapies in Multiple Sclerosis. Neurology. 105(4) e213907. doi:10.1212/WNL.0000000000213907
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Nov 6, 2025 • 4min

Neurotoxicity Imaging in Children and Young Adults After CAR T-Cell Therapy for B-Cell Malignancies

Dr. Alison Christy and Dr. Jennifer L. McGuire discuss neuroimaging findings linked to ICANS, exploring whether specific imaging patterns correlate with distinct neurologic symptoms. Show citation: McGuire JL, Pinto S, Erdogan EN, et al. Neuroimaging Findings in Children and Young Adults With Neurotoxicity After CAR T-Cell Therapy for B-Cell Malignancies. Neurology. 2025;105(7):e214086. doi:10.1212/WNL.0000000000214086
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Nov 6, 2025 • 4min

Neurotoxicity Imaging in Children and Young Adults After CAR T-Cell Therapy for B-Cell Malignancies

Dr. Alison Christy and Dr. Jennifer L. McGuire discuss neuroimaging findings linked to ICANS, exploring whether specific imaging patterns correlate with distinct neurologic symptoms. Show citation: McGuire JL, Pinto S, Erdogan EN, et al. Neuroimaging Findings in Children and Young Adults With Neurotoxicity After CAR T-Cell Therapy for B-Cell Malignancies. Neurology. 2025;105(7):e214086. doi:10.1212/WNL.0000000000214086
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Nov 5, 2025 • 4min

Optic Nerve Inclusion in the 2024 McDonald Criteria Revisions – Part 3

In the final episode of this three-part series, Dr. Jeff Lambe addresses practical considerations surrounding the inclusion of the optic nerve as a topography for demonstrating dissemination in space. Show citation: Montalban X, Lebrun-Frénay C, Oh J, et al. Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Lancet Neurol. 2025;24(10):850-865. doi:10.1016/S1474-4422(25)00270-4
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Nov 4, 2025 • 4min

Optic Nerve Inclusion in the 2024 McDonald Criteria Revisions – Part 2

In part two of this three-part series, Dr. Jeff Lambe outlines how the optic nerve is being incorporated as one of five topographies used to demonstrate dissemination in space. Show citation: Montalban X, Lebrun-Frénay C, Oh J, et al. Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Lancet Neurol. 2025;24(10):850-865. doi:10.1016/S1474-4422(25)00270-4
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Nov 3, 2025 • 3min

Optic Nerve Inclusion in the 2024 McDonald Criteria Revisions – Part 1

In part one of this three-part series, Dr. Jeff Lambe discusses the rationale for including the optic nerve in the 2024 revisions to the McDonald criteria. Show citation: Montalban X, Lebrun-Frénay C, Oh J, et al. Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Lancet Neurol. 2025;24(10):850-865. doi:10.1016/S1474-4422(25)00270-4
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Oct 31, 2025 • 3min

Persistent Postictal Central Apnea in Focal Seizures

Dr. Katie Krulisky and Dr. Stefano Meletti discuss the incidence and characteristics of postictal central apnea in focal seizures. Show citation: Meletti S, Burani M, Ballerini A, et al. Persistent Postictal Central Apnea in Focal Seizures: Incidence, Features, and Imaging Findings. Neurology. 2025;105(4):e213856. doi:10.1212/WNL.0000000000213856

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