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Renowned investor Kevin Ryan discusses his interest in healthcare, his investments in the sector, and his plans for a robotics fund and a social impact fund. The speaker emphasizes their long-term perspective, entrepreneurial mindset, and focus on high-risk/high-return investments. The chapter explores the concept of bankruptcies as a natural part of the business ecosystem and discusses the decrease in valuations of publicly traded companies. It also explores the challenges and success of starting a company, using the example of Gil Group.

Connie & Alex interview Max Chafkin, a columnist for Bloomberg Businessweek and the author of The Contrarian: Peter Thiel and Silicon Valley's Pursuit of Power, a captivating new biography of Peter Thiel, the legendary Silicon Valley dealmaker turned right-wing political operator. Music: 1. "Inspired" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3918-inspired)2. "Blippy Trance" by Kevin MacLeod (https://incompetech.filmmusic.io/song/5759-blippy-trance)3. "Dream Catcher" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4650-dream-catcher)4. "Pamgaea" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4193-pamgaea)5. "EDM Detection Mode" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3687-edm-detection-mode)License: https://filmmusic.io/standard-license Learn more about your ad choices. Visit megaphone.fm/adchoices

Connie interviews Peter Relan,  founder of the incubator YouWeb, about writing the first check for Discord and managing all of the VCs that were competing to get into the deal. Music: 1. "Inspired" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3918-inspired)2. "Blippy Trance" by Kevin MacLeod (https://incompetech.filmmusic.io/song/5759-blippy-trance)3. "Dream Catcher" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4650-dream-catcher)4. "Pamgaea" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4193-pamgaea)5. "EDM Detection Mode" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3687-edm-detection-mode)License: https://filmmusic.io/standard-license Learn more about your ad choices. Visit megaphone.fm/adchoices

Connie & Alex work their way through this week's news, including excerpts from Connie's interview with Bain Capital chairman Steve Paliuca; Carlyle cofounder David Rubenstein; Jean Salata, the CEO and founding partner of Baring Private Equity Asia; and Sheila Patel, the former chair of Goldman Sachs Asset Management and today the vice chairman of B Capital. Music: 1. "Inspired" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3918-inspired)2. "Blippy Trance" by Kevin MacLeod (https://incompetech.filmmusic.io/song/5759-blippy-trance)3. "Dream Catcher" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4650-dream-catcher)4. "Pamgaea" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4193-pamgaea)5. "EDM Detection Mode" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3687-edm-detection-mode)License: https://filmmusic.io/standard-license Learn more about your ad choices. Visit megaphone.fm/adchoices

Connie & Alex skim through some of the week's most interesting tech stories and then talk to Mark Suster, a General Partner at Upfront Ventures, a seed- and early growth-stage venture firm based in Los Angeles.Music: 1. "Inspired" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3918-inspired)2. "Dream Catcher" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4650-dream-catcher)3. "Blippy Trance" by Kevin MacLeod (https://incompetech.filmmusic.io/song/5759-blippy-trance)4. "Pamgaea" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4193-pamgaea)5. "EDM Detection Mode" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3687-edm-detection-mode)License: https://filmmusic.io/standard-license Learn more about your ad choices. Visit megaphone.fm/adchoices

Connie & Alex talk tech news and then quiz Neil Malhotra, a professor of political economics at Stanford's business school, on why Governor Newsom's recall election could have a big impact on tech for years to come. Music: 1. "Inspired" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3918-inspired)2. "Dream Catcher" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4650-dream-catcher)3. "Blippy Trance" by Kevin MacLeod (https://incompetech.filmmusic.io/song/5759-blippy-trance)4. "Pamgaea" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4193-pamgaea)5. "EDM Detection Mode" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3687-edm-detection-mode)License: https://filmmusic.io/standard-license Learn more about your ad choices. Visit megaphone.fm/adchoices

Connie & Alex interview the founders of Kalshi, a new Sequoia-backed startup that aims to let people wager on future events ranging from economics to the weather to public health, and then Connie talks to new Andreessen Horowitz GP Arianna Simpson about crypto gaming.Music: 1. "Inspired" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3918-inspired)2. "Dream Catcher" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4650-dream-catcher)3. "Blippy Trance" by Kevin MacLeod (https://incompetech.filmmusic.io/song/5759-blippy-trance)4. "Bleeping Demo" by Kevin MacLeod (https://incompetech.filmmusic.io/song/7012-bleeping-demo)5. "Pamgaea" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4193-pamgaea)6. "EDM Detection Mode" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3687-edm-detection-mode)License: https://filmmusic.io/standard-license Learn more about your ad choices. Visit megaphone.fm/adchoices

Connie & Alex interview New York Times tech reporter Sheera Frenkel,  co-author of An Ugly Truth: Inside Facebook’s Battle for Domination; and then Connie chats with early-stage VC Jeff Clavier about all of the big money from groups like Tiger that is driving up startup valuations.Music: 1. "Inspired" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3918-inspired)2. "Dream Catcher" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4650-dream-catcher)3. "Blippy Trance" by Kevin MacLeod (https://incompetech.filmmusic.io/song/5759-blippy-trance)4. "Bleeping Demo" by Kevin MacLeod (https://incompetech.filmmusic.io/song/7012-bleeping-demo)5. "Pamgaea" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4193-pamgaea)6. "EDM Detection Mode" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3687-edm-detection-mode)License: https://filmmusic.io/standard-license Learn more about your ad choices. Visit megaphone.fm/adchoices

Connie & Alex talk tech news and then dive into it with TechCrunch founder and crypto investor Michael Arrington of Arrington Capital.Music: 1. "Inspired" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3918-inspired)2. "Dream Catcher" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4650-dream-catcher)3. "Blippy Trance" by Kevin MacLeod (https://incompetech.filmmusic.io/song/5759-blippy-trance)4. "Pamgaea" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4193-pamgaea)5. "EDM Detection Mode" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3687-edm-detection-mode)License: https://filmmusic.io/standard-license Learn more about your ad choices. Visit megaphone.fm/adchoices

Connie & Alex pick their top two tech stories of the week and then chat with Renata Quintini and Roseanne Wincek of Renegade Partners, a new fund that has just raised its first fund of $100 million to help startups navigate the "supercritical stage."Music: 1. "Inspired" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3918-inspired)2. "Dream Catcher" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4650-dream-catcher)3. "Blippy Trance" by Kevin MacLeod (https://incompetech.filmmusic.io/song/5759-blippy-trance)4. "Pamgaea" by Kevin MacLeod (https://incompetech.filmmusic.io/song/4193-pamgaea)5. "EDM Detection Mode" by Kevin MacLeod (https://incompetech.filmmusic.io/song/3687-edm-detection-mode)License: https://filmmusic.io/standard-license Learn more about your ad choices. Visit megaphone.fm/adchoices