

ZOE Science & Nutrition
ZOE
The world’s top scientists explain the latest health, nutrition, and gut health research and translate it into practical advice to improve your health & weight. Join ZOE Science & Nutrition, on a journey of scientific discovery. Hosted by Jonathan Wolf.
Episodes
Mentioned books

11 snips
Apr 2, 2026 • 59min
How to tell if your poo is normal and the 5 warning signs you shouldn't ignore | Dr Trisha Pasricha
Dr Trisha Pasricha, a Harvard-trained gastroenterologist and neurogastroenterology researcher, explains how stool reveals health clues. Short, clear takes cover stool colour and consistency, bathroom posture, fibre and frequency, and the gut–brain link. Practical signs to watch and everyday habits that quietly harm your gut are highlighted.

4 snips
Mar 31, 2026 • 14min
Most replayed moment: Lessons from a 5000-year-old diet | Frank Maixner & Tim Spector
Tim Spector, epidemiology professor decoding the microbiome, and Frank Maixner, archaeogeneticist who analyzed the Iceman, explore ancient diet clues. They discuss the Iceman’s preserved stomach contents and high-fat meat choices. They reveal a surprisingly diverse ancient gut microbiome and consider how modern lifestyles may have reduced microbial variety.

40 snips
Mar 26, 2026 • 1h 2min
The first 1000 days: The 5 ways early nutrition determines your future risk of obesity and heart disease | Prof Lucilla Poston & Dr Federica Amati
Prof Lucilla Poston, a maternal and fetal health researcher, and Dr Federica Amati, ZOE’s head nutritionist, explore the first 1,000 days of life. They discuss prenatal nutrition, how parental health shapes eggs and sperm, pregnancy diet and safe movement, breastfeeding and weaning, and why many packaged baby foods can be misleading. Practical, science-backed guidance for nurturing lifelong health.

41 snips
Mar 24, 2026 • 13min
Most replayed moment: Reduce anxiety by improving your gut health | Uma Naidoo
Uma Naidoo, Harvard-trained nutritional psychiatrist who studies the gut-brain connection. She explores how gut microbes influence neurotransmitters like serotonin and GABA. She explains gut-to-brain wiring via the vagus nerve. Practical tips include simple diet swaps, adding colourful plants, movement, and calming food principles.

120 snips
Mar 19, 2026 • 1h 3min
How to feed the 50 gut bacteria that shrink body fat, calm inflammation and cut cholesterol | Prof Nicola Segata & Prof Sarah Berry
Prof Sarah Berry, King's College nutrition expert, and Prof Nicola Segata, computational microbiome pioneer, explain how 50 gut bacteria link to body fat, inflammation and cholesterol. They reveal how these microbes were ranked from 34,000 samples. They discuss unknown microbial “dark matter,” why plant diversity and whole‑food prebiotics shift microbes in weeks, and how some species resist change.

43 snips
Mar 17, 2026 • 16min
Most replayed moment: Carbs: the good, the bad, and the misunderstood | Tim Spector
Tim Spector, professor of genetic epidemiology and microbiome researcher, talks carbs: what they are and how complexity affects digestion. He highlights healthier choices like sourdough, rye and legumes. He covers timing, mixing carbs with fats and fiber to lower spikes, and how cooling cooked starches can boost resistant starch.

118 snips
Mar 12, 2026 • 53min
Professor Tim Spector: I was wrong about Vitamin D & sunlight! The 7 health habits he's changed his mind about
Professor Tim Spector, epidemiologist and microbiome researcher, reflects on seven health beliefs he has revised after new evidence. He discusses vitamin D and sunlight, oral health linked to brain aging, microplastics in blood, omega-3 testing and food-based boosts, personalized B12 and folate choices, and shifting exercise and sleep habits.

45 snips
Mar 10, 2026 • 14min
Most replayed moment: What can we learn from the man who’s trying to live forever? | Bryan Johnson & Tim Spector
Tim Spector, epidemiology professor and microbiome expert, and Bryan Johnson, entrepreneur and longevity self-experimenter, discuss a data-driven quest to slow aging. They cover his vegan calorie strategy, extensive supplement routine and biomarker tracking. They debate whole foods versus high-dose nutrients and imagine home testing and algorithmic health management. Bryan also shares five sleep habits.

105 snips
Mar 5, 2026 • 57min
Tired, anxious, gaining weight? It could be your hormones | Dr Helen O’Neill
Dr Federica Amati, ZOE head nutritionist who studies diet–gut–hormone links, and Dr Helen O’Neill, UCL reproductive geneticist with large-scale hormone testing experience, discuss hormones and health. They explore how hormones affect fatigue, anxiety, weight and fertility. Topics include thyroid, PCOS, sperm health, gut hormones, diet strategies, testing and why better data matters.

52 snips
Mar 3, 2026 • 16min
Recap: How to build strength from the comfort of your home | Andy Galpin
Andy Galpin, human performance expert and professor in strength and muscle physiology. He shows how to build meaningful strength at home with short, twice-weekly full-body sessions. Topics include using bands and bodyweight, compound movements like step-ups, supersets for efficiency, and fitting training around running and busy schedules.


