Hormones, Metabolism & You!

Cassie Smith
undefined
Jan 18, 2026 • 1h 15min

94: Your Labs Are Normal but You Feel Awful - The Hidden Gut Inflammation Blocking Hormone Healing with Josh Dech

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if your lingering thyroid and hormone symptoms aren’t a lab problem at all, but a gut inflammation issue hiding beneath “normal” results? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with holistic nutritionist and physician consultant Josh Dech to explore a core idea many patients never hear: your thyroid and hormone symptoms may be driven by hidden gut inflammation, even when labs look “normal.” Josh explains how gut dysfunction can interfere with hormone signaling, disrupt metabolism, and fuel chronic fatigue, brain fog, and stubborn symptoms. They also discuss common root drivers like toxins, infections, nutrient deficiencies, poor sleep, and chronic stress, plus practical steps to support healing without extreme protocols. Key Topics Covered Why thyroid and hormone symptoms can persist even with “normal” lab results How gut inflammation can block hormone signaling and contribute to fatigue and brain fog Gut health on a spectrum: from mild symptoms to severe inflammatory conditions The “why” behind symptoms vs. labels and diagnoses Mold and environmental exposures as potential hidden drivers for some people The “three buckets” framework: toxins, microbes, and deficiencies The role of sleep, stress, and lifestyle in gut and immune function Why some “healthy” foods can still be personal triggers for certain individuals Supporting drainage and detox pathways as part of recovery Simple, sustainable steps for improving gut and overall health About the Guest Josh Dech is a Holistic Nutritionist and Physician Consultant specializing in Crohn’s disease, ulcerative colitis, and severe IBS. He is known for helping reverse over 400 cases of Crohn’s and colitis through a root-cause, holistic approach to gut health, conditions long considered irreversible within conventional care. Josh has worked alongside some of the world’s most respected medical professionals and has become a trusted educator in the field of digestive and autoimmune health. He hosts a globally ranked top 2 percent podcast, has appeared on international television, and currently serves as a medical lecturer for Priority Health Academy. Today, Josh focuses on educating both physicians and the public on integrative, evidence-informed strategies for healing chronic digestive diseases and restoring long-term gut health. Connect with Josh Dech Facebook: https://www.facebook.com/JoshDechInstagram: https://www.instagram.com/joshdech.health/YouTube: https://www.youtube.com/@joshdech 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠
undefined
Jan 11, 2026 • 51min

93: Why You Can’t Lose Weight (It’s Your Hormones, Not Your Willpower)

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if weight loss isn’t about discipline, motivation, or trying harder, but about understanding what your hormones are actually doing? In this powerful New Year mash-up episode of Hormones, Metabolism, and You, Dr. Cassie Smith brings together the most impactful insights from three standout conversations to explain why traditional diets fail so many women and what truly supports sustainable weight loss. Drawing from expert guidance by Tamar Samuels, Shana Hussin, and Terri DeNeui, this episode reframes weight gain as a hormonal and metabolic signal, not a personal failure. Listeners will learn how stress, gut health, insulin resistance, PCOS, thyroid dysfunction, and age-related hormone shifts quietly sabotage fat loss, and why fasting, restriction, and one-size-fits-all diets often make things worse. This episode is especially for women in their 30s, 40s, and 50s who feel stuck, exhausted, and frustrated despite doing “all the right things.” Episode Highlights Why weight gain is often driven by hormones, not willpower How cortisol, leptin, insulin, and thyroid hormones block fat loss What really changes hormonally in your 30s, 40s, and 50s Why testosterone and progesterone decline earlier than most women realize The truth about fasting and why it backfires for stressed women How gut health directly affects metabolism and hormone balance Why PCOS, thyroid issues, and insulin resistance require targeted nutrition How restrictive diets and under-eating damage hormones long term Why protein needs increase with age and how much women actually need Why the scale lies and what markers matter more than weight Key Topics Covered It’s Not Your Fault: Understanding Hormone Shifts Hormonal changes begin earlier than menopause Testosterone loss affects muscle, mood, metabolism, and energy Progesterone decline impacts sleep, stress tolerance, and fat storage Weight gain is often a biological response, not a behavior issue The Hidden Conditions Blocking Weight Loss PCOS, thyroid dysfunction, and insulin resistance explained simply How cortisol and chronic stress stop fat burning Why leptin resistance develops from dieting and fasting Why blood sugar balance matters more than calorie counting Food as Medicine, Not Punishment Why personalized nutrition beats rigid diet rules Protein targets for women as they age The real role of carbs and fats in hormone health Why meal timing and eating enough matters Lifestyle Changes That Actually Work Circadian rhythm alignment and stress reduction Gut health as the foundation of hormone metabolism Why extreme fasting, overtraining, and restriction do harm Root-cause care vs symptom suppression Final Takeaway This New Year, the answer isn’t another diet, cleanse, or restriction plan. Sustainable weight loss happens when you: Support your hormones Heal your gut Eat enough of the right foods Reduce stress Stop fighting your biology Your body isn’t broken. It’s communicating. 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠
undefined
Jan 4, 2026 • 56min

92: Your Hormones Aren’t the Problem - The Shocking Root Cause Behind Fatigue, Weight Gain, and Brain Fog with Dr. Kelly McCann

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if your hormone symptoms aren’t a hormone problem at all, but warning signs of deeper toxic, gut, and immune stress your body has been carrying for years? In this powerful episode of Hormones Metabolism in You, Dr. Cassie Smith sits down with Dr. Kelly K. McCann, MD, to unpack why hormone symptoms like fatigue, weight gain, brain fog, mood changes, and stubborn metabolic dysfunction are often not hormone problems at all. Instead, Dr. McCann explains how these symptoms are signals pointing to deeper root causes such as environmental toxin exposure, mold, gut dysfunction, immune dysregulation, and chronic inflammation. Together, they challenge the conventional approach of treating hormones in isolation and highlight why normal lab results do not always mean the body is functioning optimally. This conversation explores how everyday exposures from water contamination and plastics to non-stick cookware, pesticides, and personal care products can silently disrupt thyroid function, metabolism, and hormone signaling. The episode also dives into the critical gut hormone immune connection, mold related illness, nutrient depletion, mitochondrial dysfunction, and the concept of the cell danger response. About the Guest Dr. Kelly K. McCann, MD is a board certified physician trained in internal medicine and pediatrics, with advanced training in integrative and functional medicine. Her work focuses on the impact of environmental exposures on human health, including mold illness, chemical toxicity, chronic infections, immune dysregulation, and mast cell activation syndrome. Dr. McCann specializes in treating complex chronic illness by addressing root causes such as toxic burden, gut permeability, mitochondrial dysfunction, and nervous system imbalance. She is the founder of The Spring Center in Southern California and provides care to patients across multiple states. She also teaches and writes extensively on the intersection of environment, immunity, hormones, and healing. Key Topics Covered Why hormone symptoms are messengers, not the root problem Environmental toxins and their impact on thyroid and hormone signaling Mold exposure and its role in chronic illness and metabolic dysfunction The gut hormone immune axis and why gut health is inseparable from hormone health How plastics, PFAS, pesticides, and contaminated water disrupt endocrine function Food related mold and toxin exposure, including grains, corn, and peanuts Heavy metals, mercury accumulation, and bioaccumulation in the body Why many patients struggle despite “normal” lab results Critical labs often missed in conventional care, including thyroid conversion markers The role of mitochondrial dysfunction and the cell danger response Chronic stress, trauma, and nervous system dysregulation in hormone imbalance Why perimenopause often reveals accumulated toxic burden Small, practical steps to reduce toxic load and support healing Links & Resources:  Dr. Kelly K. McCann, MD 🔗 Official Websitehttps://drkellymccann.com/ 🔗 The Spring Centerhttps://thespringcenter.com/ 🔗 LinkedIn Profilehttps://www.linkedin.com/in/dr-kelly-mccann/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠
undefined
Dec 28, 2025 • 55min

91: You Feel Tired but Labs Look Normal - The Hidden Nitric Oxide Deficiency No One Tests For with Dr. Nathan Bryan

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if many hormone, thyroid, and energy problems come down to a single overlooked molecule your body is quietly running out of? In this episode of Hormones Metabolism in You, Dr. Cassie Smith sits down with nitric oxide expert Dr. Nathan Bryan to explore why nitric oxide is one of the most overlooked yet essential molecules in human health. Together, they unpack nitric oxide’s powerful role in hormone signaling, thyroid function, gut motility, immune defense, blood flow, and mitochondrial energy production. Dr. Bryan explains how nitric oxide deficiency can contribute to fatigue, hormone resistance, insulin resistance, poor circulation, and chronic inflammation, even when labs appear “normal.” They also discuss how modern lifestyle factors such as aging, chronic stress, poor diet, fluoride exposure, antiseptic mouthwash use, and long term antacid use can significantly impair nitric oxide production. Most importantly, this conversation offers practical, science backed strategies listeners can apply immediately to support nitric oxide levels and improve overall hormone health, energy, and longevity. About the Guest Dr. Nathan Bryan holds a Bachelor of Science in Biochemistry from the University of Texas at Austin and earned his doctoral degree from Louisiana State University School of Medicine in Shreveport, where he received the Dean’s Award for Excellence in Research. He completed postdoctoral training as a Kirschstein Fellow at Boston University School of Medicine in the Whitaker Cardiovascular Institute. In 2006, Dr. Bryan joined the faculty at the University of Texas Health Science Center at Houston under the recruitment of Nobel Laureate Dr. Ferid Murad. With over two decades of experience in nitric oxide research, he has made significant contributions to the field, resulting in numerous US and international patents and clinically impactful technologies. Dr. Bryan is also a successful entrepreneur and Founder and CEO of Nitric Oxide Innovations, LLC, where he continues to advance nitric oxide based therapies and molecular medicine worldwide. Key Topics Covered What nitric oxide is and why it is essential for human health How nitric oxide influences hormone signaling and receptor sensitivity The connection between nitric oxide and thyroid function Nitric oxide’s role in gut motility, digestion, and the oral microbiome How nitric oxide supports immune defense and inflammation control Mitochondrial energy production and cellular oxygen delivery Why nitric oxide production declines with age How stress, poor diet, and environmental exposures impair nitric oxide The impact of fluoride, antiseptic mouthwash, and antacids on nitric oxide production Common symptoms associated with nitric oxide deficiency How impaired blood flow affects hormone delivery and tissue response Links & Resources Website: https://drnathansbryan.com/LinkedIn: https://www.linkedin.com/in/drnathansbryan Nitric Oxide Education:https://www.n1o1.com/https://www.no2u.com/https://www.nitricoxideinnovations.com/ Shop N1O1 Products: https://www.awin1.com/cread.php?awinmid=115399&awinaffid=2702698 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠
undefined
Dec 21, 2025 • 1h 7min

90: Medicine Is Falling Behind - The Shocking Gaps in Nutrition and Gut Health Training with Dr. Johnny Hadac

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the biggest problem in modern medicine isn’t a lack of treatments, but a lack of training in nutrition, gut health, and root cause care? In this episode, Dr. Cassie Smith welcomes back Dr. Johnny Hadac, now a family medicine resident, to reflect on how his medical training has evolved and where traditional healthcare continues to fall short. Together, they unpack the realities of residency, the lack of meaningful nutrition and gut health education in medical training, and why chronic disease cannot be solved without addressing inflammation, hormones, and the gut. Dr. Hadac shares what he has learned during his first months of residency, how functional medicine principles have shaped his approach to patient care, and why proactive, relationship based medicine leads to better outcomes. The conversation also explores the broken insurance driven healthcare system, the importance of provider education, and how social media can help close the knowledge gap. They also dive into Dr. Hadac’s bestselling cookbook, which combines practical, affordable recipes with extensive education on gut health, insulin resistance, fiber, and hormone balance. This episode offers hope for the future of medicine and practical tools for patients and providers alike. About the Guest Dr. Johnny Hadac is a family medicine resident, physician, certified nutritionist, and culinary medicine specialist. He is the founder of Total Weight Loss and Muscle Dummies, a global health community with over two million followers focused on affordable, science based nutrition and lifestyle habits. Dr. Hadac is a bestselling cookbook author and app developer who blends medical science with real world practicality. His work centers on gut health, insulin resistance, metabolic health, and sustainable weight loss through high fiber, high protein, whole food nutrition. Through social media, education, and clinical practice, he is helping reshape how people understand health, food, and disease prevention. Key Topics Covered What residency is really like and how medical education is evolving Major gaps in nutrition and gut health training for physicians Why gut health is foundational to hormone balance and chronic disease The role of fiber, fermented foods, and inflammation in metabolic health How functional medicine principles improve patient outcomes Challenges of insurance driven healthcare systems Direct primary care and proactive medicine models Social media as a tool for patient and provider education Insulin resistance and metabolic dysfunction Practical, accessible nutrition strategies for long term health Connect with Dr. Johnny Hadac LinkedIn: https://www.linkedin.com/in/johnny-hadac-6a38aa126/Instagram: https://www.instagram.com/drjohnnyhadac/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠
undefined
Dec 14, 2025 • 58min

89: The FDA Finally Admits the Truth – The Shocking Correction That Changes Hormone Therapy Forever with Dr. Terri DeNeui

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the biggest breakthrough in women’s health this decade is the long overdue reversal of a warning that never should have existed in the first place? In this timely episode, Dr. Cassie Smith sits down with hormone expert and healthcare reform advocate Dr. Terri DeNeui, DNP, APRN, ACNP-BC to unpack the FDA’s landmark decision to remove the black box warning from estrogen containing HRT. For the first time in over twenty years, science and policy finally align, creating safer and more accessible options for millions of women. Dr. Cassie and Dr. Terri break down what the original research actually showed, how estrogen became unfairly feared, and why the updated guidelines are long overdue. They explore the benefits of estrogen, progesterone, and testosterone for women, clearing up misconceptions and highlighting the need for better hormone education among providers and patients. With clinical insights and decades of experience, this episode reveals the truth about hormone therapy, why women have suffered needlessly for two decades, and how the removal of the black box warning can reshape the future of women's health.   About the Guest Dr. Terri DeNeui, DNP, APRN, ACNP-BC is a board certified Adult Acute Care Nurse Practitioner, entrepreneur, Chief Science Officer, and leading voice in healthcare reform. She serves on the Executive Committee of the America First Policy Institute and the America First Women’s Initiative, contributing to national healthcare policy. A Summa Cum Laude graduate of the University of Texas at Arlington, Dr. DeNeui holds the Doctor of Nursing Practice degree. She is the Founder of EVEXIAS Medical Centers and EVEXIAS Health Solutions, and creator of the EvexiPEL Method of hormone optimization, used globally and supported by outcomes research. She is also lead teaching faculty for the A4M World Congress on Anti Aging Medicine. Her published work includes the peer reviewed article Best Practices in Care for the Menopausal Patient and the bestselling book Hormone Havoc: Dispelling the Myths and Misconceptions about Hormones in Women and Men.   Key Topics Covered What the FDA’s black box removal means for women How the Women’s Health Initiative was misinterpreted Estrogen’s role in brain, heart, bone, gut, metabolic, and vaginal health How fear based messaging led to unnecessary suffering Benefits and safety of micronized progesterone Why testosterone is essential for women’s mood, libido, muscle, and cognition Early testosterone decline and how it affects daily life Hormones, intimacy, and relationship well being Why hormone therapy requires gut health evaluation and individualized dosing Provider education gaps and self advocacy for women Recognizing hormone decline across the lifespan Why better policy and access to hormone therapy are urgently needed Connect with Dr. Terri DeNeui Instagram: https://www.instagram.com/drterrideneui/ Facebook: https://www.facebook.com/DrTerriDeNeui/LinkedIn: https://www.linkedin.com/in/terri-deneuiWebsite: https://www.evexias.comPodcast: https://podcasts.apple.com/us/podcast/the-dr-terri-show/id1757438909Email: terri.deneui@evexias.com Phone: (214) 202-4727 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠
undefined
Dec 7, 2025 • 60min

88: Why Your Thyroid Is in Crisis – The Hidden Triggers Driving Graves Disease with Dr. Eric Osansky

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the key to reversing Graves disease starts with uncovering the hidden triggers your thyroid has been reacting to all along? In this information rich episode, Dr. Cassie Smith sits down with functional medicine practitioner and thyroid expert Dr. Eric Osansky to break down the realities of Graves disease and hyperthyroidism. They explore why diagnosis is often delayed, what truly drives autoimmune thyroid conditions, and how gut health, nutrient deficiencies, infections, stress, and environmental toxins all influence thyroid function. Dr. Osansky also shares his personal remission journey and offers practical guidance, testing recommendations, and natural treatment options. This episode is essential for anyone navigating Graves disease, hyperthyroidism, or persistent thyroid symptoms and searching for a root cause approach. About the Guest Dr. Eric Osansky is a functional medicine practitioner with more than 15 years of clinical experience in chiropractic care, nutrition, and autoimmune thyroid health. After reversing his own Graves disease in 2009, he dedicated his career to helping others heal naturally. He is the author of Natural Treatment Solutions for Hyperthyroidism and Graves Disease, Hashimoto’s Triggers, and The Hyperthyroid Healing Diet, and hosts the Save My Thyroid podcast. He holds a Master’s degree in Human Nutrition and Functional Medicine and advanced certifications in nutrition and herbal therapy. Key Topics Covered How Graves disease differs from hypothyroidism and why hyperthyroidism is often misunderstood The environmental, immune, and lifestyle triggers that drive autoimmune thyroid disease Stress, infections, toxins, and overtraining as common contributors How gluten, corn, dairy, and high sodium intake influence leaky gut and autoimmunity The thyroid gut connection and how dysbiosis, H. pylori, and nutrient malabsorption affect thyroid function Essential nutrients for healthy thyroid hormone production and conversion The most important labs thyroid patients should request How H. pylori, viruses, mold, and stealth infections impact autoimmunity Conventional treatments including methimazole, PTU, beta blockers, and when they are necessary Natural therapies such as bugleweed, motherwort, lemon balm, selenium, and L carnitine The role of LDN and why results vary in Graves disease Why healing requires sleep, stress management, gut repair, movement, and nutrient optimization How to advocate for your health when providers overlook root causes Connect with Dr. Eric Osansky Facebook: https://www.facebook.com/NaturalThyroidTreatment/YouTube: https://www.youtube.com/@NaturalThyroidDoctorInstagram: https://www.instagram.com/drericosansky/Website: https://savemythyroid.com 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠
undefined
Nov 30, 2025 • 52min

87: Stop Blaming Age – The Shocking Hidden Causes of Fatigue, Weight Gain, and Mood Swings with McCall McPherson and Dr. Tyna Moore

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the real answers to your midlife hormone struggles are not in a pill, but in understanding the deeper connections between your thyroid, metabolism, and the way your body changes over time? In this powerhouse mashup episode, Dr. Cassie Smith brings together two of the most outspoken and experienced voices in functional medicine: McCall McPherson, thyroid expert and founder of Modern Thyroid Clinic, and Dr. Tyna Moore, a naturopathic physician and metabolic health disruptor. Together, they unpack the complex hormonal shifts women experience—especially during perimenopause and menopause—and share real-world strategies to reclaim health, energy, and vitality. From GLP-1 medications to progesterone deficiency, thyroid misdiagnosis to strength training, this episode covers the most pressing questions women are asking today. You’ll hear personal insights, clinical wisdom, and evidence-based tools for navigating hormone changes, gut issues, inflammation, and mental health with clarity and confidence. 👤 About the Guests McCall McPherson is the founder of Modern Thyroid Clinic and Thyroid Nation, a TEDx speaker, physician assistant, and a thyroid warrior herself. Her mission is to end the suffering of millions with thyroid disorders through expert care, patient advocacy, and empowering education. Dr. Tyna Moore is a licensed Naturopathic Physician and Chiropractor specializing in resilient metabolic health, regenerative medicine, and clinical strength training. She's also the host of The Dr. Tyna Show and a strong advocate for women’s health and muscle-centric aging. 🔑 Key Topics Covered ✅ The truth about GLP-1s like semaglutide and tirzepatide—and what microdosing really means ✅ When to consider hormone therapy and why most women need progesterone earlier than expected ✅ Why muscle is your best metabolic and hormone-supporting organ ✅ The thyroid–estrogen connection and how hormone shifts during menopause impact thyroid function ✅ How GLP-1s can expose hidden dysfunctions like gut dysbiosis and low estrogen ✅ Why low progesterone may be behind your irritability, sleep issues, and anxiety ✅ The importance of comprehensive thyroid testing (FT3, FT4, RT3) and individualized care ✅ Gut–hormone–brain axis: how estrogen and thyroid hormones influence mood and digestion ✅ Alcohol and inflammation: the honest truth about even “just one glass” ✅ Empowering women to advocate for their health in a broken system ✅ The generational shift in how women approach midlife and aging 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠
undefined
Nov 23, 2025 • 54min

86: Your Brain Isn’t Broken – The Fastest Way to Rewire Anxiety and Hormones with Dr. Caroline Leaf

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the key to healing your hormones has been hidden in your thought patterns all along? In this transformational episode, Dr. Cassie Smith sits down with renowned clinical neuroscientist and communication pathologist Dr. Caroline Leaf to explore how mental health and hormonal health are deeply intertwined. They dive into the science of neuroplasticity—our brain’s ability to rewire itself—and how harnessing this power can help women break free from anxiety, depression, and hormonal imbalances. Dr. Leaf introduces her 5-step Neurocycle™ process, explains why anxiety and depression are not diseases but signals, and shows how rewiring our thought patterns can improve everything from thyroid function to weight loss. If you've ever struggled with chronic stress, burnout, mood swings, or stubborn hormone issues, this episode offers hope, science, and practical tools to help you heal from the inside out.   👤 About the Guest: Dr. Caroline Leaf is a clinical neuroscientist, communication pathologist, bestselling author of 19 books, and host of the award-winning podcast Cleaning Up the Mental Mess. With over 50 million downloads and a global following, Dr. Leaf is a pioneer in the field of mind-brain research and mental health. Her work bridges neuroscience, mental wellness, and functional healing through a holistic lens. 🔗 Website: www.drleaf.com 🎙️ Podcast: Cleaning Up the Mental Mess 📸 Instagram: @drcarolineleaf   🔑 Key Topics Covered: The critical difference between your mind and your brain—and why it matters for healing Understanding neuroplasticity and how thoughts physically rewire your brain and body Why anxiety, depression, and ADHD are not diseases but signals The Neurocycle™: A 5-step process to break toxic thinking and form healthier patterns The 63-day habit rewiring rule (not just 21!) How hormones respond to thought patterns and emotional states The mind-gut-hormone axis and why doctors often overlook it Why mental and emotional trauma can literally reshape your endocrine system The importance of self-directed mind management in chronic illness, burnout, and hormone recovery How to recognize when you're in the “dip” of transformation—and what to do about it 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠
undefined
Nov 16, 2025 • 45min

85: What If Your Migraines Aren’t Just in Your Head? – The Hidden Root Causes with Dr. Meg Mill

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< Could your migraines be less about pain in your head—and more about hidden imbalances in your hormones, gut, and environment? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with functional medicine pharmacist Dr. Meg Mill to uncover the surprising root causes of chronic migraines—especially in women navigating hormonal shifts like menstruation, perimenopause, and menopause. Together, they explore how more than 50 potential triggers can fuel migraine symptoms, from dehydration and poor sleep to gut health issues, estrogen dominance, and histamine intolerance. Dr. Mill shares how functional medicine helps uncover these connections and provides a roadmap for lasting relief. They discuss the power of personalized migraine tracking, hormone and gut testing, and targeted protocols to reduce inflammation and rebalance the nervous system. Whether you’ve suffered for years or are newly struggling with hormone-driven headaches, this episode is a must-listen. 💡 Functional migraine solutions are within reach—no endless prescriptions required. 🔑 Key Topics Covered How hormonal shifts during perimenopause and menstruation trigger migraines Why there are 50+ potential migraine triggers—and how to uncover your unique mix Common food triggers: histamine, tyramine, nitrates, sulfites, MSG, and wine Why your environment, stress levels, and even your air quality can worsen migraines The link between estrogen dominance, progesterone deficiency, and mast cell activation The role of gut health, detoxification, and sleep in migraine prevention How histamine intolerance contributes to migraines, fatigue, anxiety, and skin issues The truth about low stomach acid, acid reflux, and poor nutrient absorption Personalized approaches vs. symptom suppression (why journaling matters) When to use testing like the DUTCH test or GI Map for hormones and gut health 👤 About the Guest: Dr. Meg Mill, PharmD, AFMCP Dr. Meg Mill is a functional medicine pharmacist, bestselling author, and host of A Little Bit Healthier podcast. With 20+ years of clinical experience, she helps women around the world resolve migraines, hormonal issues, and histamine-related symptoms. She's the founder of the Radiant Method, which empowers women to regain energy and clarity through root-cause healing. 📍 Learn more: www.megmill.com 🎧 Podcast: A Little Bit Healthier 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

The AI-powered Podcast Player

Save insights by tapping your headphones, chat with episodes, discover the best highlights - and more!
App store bannerPlay store banner
Get the app