Mind & Matter

Nick Jikomes
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Jul 6, 2023 • 1h 17min

Psychedelics, Neuroplasticity, LSD, Psilocybin, Ketamine, MDMA, Latest Psychedelic Science | Bryan Roth | 119

Send us Fan MailNick talks to Bryan Roth, MD, PhD, a Professor of Pharmacology at the University of North Carolina. Dr. Roth has been studying the molecular mechanisms of psychedelics since the 1980s. They discuss: serotonin 2A receptors in the mammalian brain; psychedelics & neuroplasticity; classic psychedelics (e.g. LSD, psilocybin, DMT) compared to drugs like ketamine & MDMA; TrkB receptors & BDNF; engineering novel drugs & psychiatric treatment methods; latest findings in psychedelic science.More psychedelic science content.*Not medical advice.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts
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5 snips
Jun 28, 2023 • 1h 29min

Psychedelics, Terence McKenna, Magic Mushrooms & Culture | Dennis McKenna | Episode 118

Send us Fan MailNick talks to ethnopharmacologist Dr. Dennis McKenna, who is the brother of psychonaut Terence McKenna and author of the book, "The Brotherhood of the Screaming Abyss." They discuss: the lives and psychedelic adventures of Dennis & Terence McKenna; experiences with psilocybin mushrooms & DMT; Carl Jung & psychology; the medical relevance of subjective psychedelic experiences; drugs, culture & society; and more.*Not medical adviceSupport the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts
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Jun 9, 2023 • 1h 37min

Psychiatry, Psychedelic Medicine, LSD for Anxiety, MDMA for Autism, Medical Education, Patient Access & Mental Health | Daniel Karlin | 117

Send us Fan MailNick talks to Daniel Karlin, MD, a board-certified physician in psychiatry, addiction medicine & clinical informatics who is the Chief Medical Officer at MindMed. They discuss: psychiatry; incentives in scientific & medical research; healthcare & mental health; psychedelics; LSD for anxiety; MDMA for autism; ibogaine derivatives for addiction; patient access & care; and more.*This content is never meant to serve as medical advice.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts
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Jun 1, 2023 • 1h 24min

The Dirty Truth About Cooking Oils (Avocado, Olive, Vegetable Oil) | Selina Wang | 116

Send us Fan MailNick talks to chemist & food scientist Dr. Selina Wang about: food quality & purity; cooking oils (avocado, olive, vegetable, etc.); fruits & vegetables; oxidation & purity of cooking oils; how to identify high quality, pure foods to purchase; and more.*Not medical advice.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts
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May 25, 2023 • 43min

Exercise Science, Nutrition, Plant vs. Animal Protein, Muscle Physiology, Sleep, Endurance vs. Resistance Training, Fat, Carbs, Amino Acids | Luc van Loon | 115

Send us Fan MailNick talks to Dr. Luc van Loon, Professor of Exercise Physiology & Nutrition at Maastricht University, about topics in exercise science, health & nutrition. They discuss: macronutrients & energy; protein quality & digestibility; endurance & resistance training; plant vs. animal protein; muscle conditioning & muscle fibers; sleep & aging; muscle physiology & metabolism; and more.To learn more about diet & metabolism, check out this content.*Not medical advice.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts
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May 8, 2023 • 54min

Marijuana, Plant Chemistry, Terpenes, Volatile Sulfur Compounds, Cannabis Industry, What Pungent Weed Smells Like & Why | Iain Oswald | 114

Send us Fan MailNick talks to Dr. Iain Oswald, who has a PhD in chemistry from the University of Texas-Dallas and is principal scientist Abstrax Tech, a cannabis research and product development company. He is an expert in using cutting edge analytical chemistry techniques to study plant chemistry and has done a lot of work to decipher the chemistry of commercial cannabis, including lesser-known compounds found in the essential oils of marijuana plants and how these relate the sensory qualities of marijuana.They discuss: the aroma of cannabis & the chemical compounds that dictate different aspects of its aroma; consumer preferences when it comes to marijuana aroma; terpenes, which are volatile compounds abundant in the plant world; his research on volatile sulfur compounds, which are found in nature in things like garlic and the aerosols produced by skunks, and how lesser-known cannabis compounds in this chemical family relate to some of the pungent, gassy/skunky odors commonly associated with marijuana; his journey from academia into the private sector, and what’s on the horizon for cannabis research.More content about cannabinoids & marijuana*Not medical advice.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts
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May 2, 2023 • 1h 14min

Alcohol Toxicity, Vaping vs. Smoking, Tobacco, Nicotine, Marijuana, Cannabis Terpenes, THC, Toxicology| Echo Rufer | 113

Send us Fan MailNick talks to board-certified toxicologist Dr. Echo Rufer. The conversation starts with a brief overview of what the science of toxicology is all about & a little bit about alcohol toxicity. They then discuss: differences between vaping and smoking; what toxins are produced through the combustion of plant material, especially tobacco & marijuana; cannabinoids like THC & CBD, as well as cannabis terpenes; relationship between dose, method of consumption & toxicity of chemical compounds; causes of the vaping-associated pulmonary injury (VAPI) associated with the vitamin E acetate that was found in some illicit market cannabis vape products; best ways to minimize toxin exposure for people who inhale plant-based consumer products such as tobacco or nicotine products or marijuana.*Not medical.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts
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Apr 13, 2023 • 1h 26min

The Age of Scientific Wellness: Why the Future of Medicine Is Personalized, Predictive, Data-Rich, and in Your Hands | Nathan Price | 112

Send us Fan MailNick talks to Dr. Nathan Price, who is a professor at the Institute of Systems Biology and Chief Science Officer of Thorne HealthTech. They discuss topics related to his new book, "The Age of Scientific Wellness: Why the Future of Medicine is Personalized, Data-Rich, and in Your Hands."Listen to Nick's previous discussion with Dr. Nathan Price.*Not medical advice.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts
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Apr 5, 2023 • 45min

Critical Periods, Neuroplasticity, Language, Synesthesia, Childhood Development, AI, DTC Marketing, Customer Segmentation, Orita.ai | Dan Brady | 111

Send us Fan MailNick talks to Daniel Brady, PhD a neuroscientist who studied sensory systems in the developing brain. Dr. Brady is also the co-founder and CEO of Orita.ai, a startup using machine learning & AI to solve data problems for direct-to-consumer brands. They discuss: critical periods of learning, childhood brain development, neuroplasticity, synesthesia, language acquisition, Orita.ai, machine learning & AI, customer segmentation, data science, and more.*Not medical advice.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts
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Mar 20, 2023 • 1h 21min

Neurogenesis, Stem Cells, Neuroplasticity, Aging, Exercise, Fasting & PTSD | Rusty Gage | 110

Send us Fan MailNick talks to Dr. Rusty Gage, a neurobiologist at the Salk Institute whose lab studies how genes & environment interact to influence brain development, including the process of adult neurogenesis. They discuss: what neurogenesis is and how it works; lifestyle factors that influence neurogenesis, such as exercise, intermittent fasting, etc.; molecular pathways involved in neurogenesis; depression & PTSD; memory formation and the function of newly born adult neurons; and more.*Not medical advice.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off.For all the ways you can support my efforts

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