

MeSsy with Christina Applegate & Jamie Lynn Sigler
Wishbone Production
On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
Episodes
Mentioned books

Mar 31, 2026 • 14sec
A MeSsy Update!
We’re taking a short break for the next few weeks while Jamie and Christina focus on their book launches. We’ll be back soon with brand new episodes!

Mar 24, 2026 • 1h 11min
Olivia Munn
This week, Christina and Jamie are joined by Olivia Munn. They discuss Olivia’s breast cancer diagnosis, how she was finally able to shed her armor, why you shouldn’t tell someone going through something to look on the bright side, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Veracity - Head to https://VeracityHealth.co and use code MESSY for up to 60% off your order.
Jones Road - Use code MESSY at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase #JonesRoadBeauty #ad

Mar 17, 2026 • 1h 16min
Carl Radke
This week, Christina and Jamie are joined by Carl Radke, Summer House cast member and host of "More Life with Carl Radke.” They discuss his journey to sobriety, holding in shame, forgiveness, behind-the-scenes of the show, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Wildgrain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants for life - when you go to https://Wildgrain.com/MESSY to start your subscription today.
Fatty15- Get an additional 15% off their 90-day subscription Starter Kit by going to https://fatty15.com/messy and using code MESSY at checkout.
Jones Road - Use code MESSY at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty #ad
Lola Blankets - Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

Mar 10, 2026 • 1h 15min
How to Heal Your Relationship With Life
This week, Christina and Jamie are joined by Jamie’s friend Ryan Weiss. They discuss how he helped her through a difficult time, the power of dance, emotional avoidance, why it’s so hard to look inward, and more.
Check out Ryan's course "How to Be Okay When Things Are Not Okay" and use code MESSY at checkout for 10% off
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Lola- Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.
Zoc Doc - Stop putting off those doctors appointments and go to https://Zocdoc.com/MESSY to find and instantly book a doctor you love today.
One Skin - Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpod

Mar 3, 2026 • 42min
We Don’t Want to Be Defined by This
This week, Christina and Jamie read listener emails and discuss the fragility of life, fighting against your body, and more,
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/MESSY #honeylovepod

Feb 24, 2026 • 1h 3min
Kelly Ripa
This week, Christina and Jamie are joined by their friend Kelly Ripa. They discuss Kelly's career and how it began at a toy fair, the processing she had to do while writing her own book, the challenges of playing yourself on television, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Fatty15 - Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MESSY and using code MESSY at checkout.
Lola - Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.
AG1 - For a limited time only, go to https://DRINKAG1.com/MESSY to get a FREE AG1 Flavor Sampler and AGZ Sampler to try all the flavors, plus FREE Vitamin D3+K2 and AG1 Welcome Kit with your first AG1 subscription order!
Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod

Feb 17, 2026 • 1h 2min
Stop Talking About It for a Minute
This week, Christina and Jamie read listener emails and discuss skincare products from childhood, crazy animal stories, not thinking too far into the future, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Wildgrain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants for life - when you go to Wildgrain.com/MESSY to start your subscription today.
Jones Road - Use code messy at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty #adArey - Slow the growth of greys and get 15% off by using code MESSY at https://Arey.com
Cheers - Same night out — way better morning with Cheers. For a limited time our listeners are getting 20% off their entire order by using code MESSY at https://CheersHealth.com #Cheers #ad
ZocDoc - Stop putting off those doctors appointments and go to https://Zocdoc.com/MESSY to find and instantly book a doctor you love today.

Feb 10, 2026 • 54min
How You Feel on the Inside Can Be Up to You
This week, Christina and Jamie read listener emails and discuss the Married... with Children reunion, catch up on their TV shows, Jamie opens up about a recent experience, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Veracity - For up to 45% off your order, head to https://VeracityHealth.co and use code MESSY

Feb 3, 2026 • 58min
I Can't Worry About Tomorrow
This week, Christina and Jamie read listener emails and discuss MS fatigue, finding little moments of self care, how to better communicate with friends, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod
Jones Road - Use code messy at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty #ad

Jan 27, 2026 • 1h 1min
Bobbi Brown
This week, Christina and Jamie are joined by Bobbi Brown. They discuss overcoming obstacles, how to elevate your mood, taking baby steps, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Lola - Get 40% off your entire order at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.
AG1 - Go to https://DRINKAG1.com/MESSY to get their best offer… get a FREE AG1 Flavor Sampler and AGZ Sampler to try all the flavors, plus FREE Vitamin D3+K2 and AG1 Welcome Kit with your first AG1 subscription order!
Warby Parker - MeSsy listeners get 15% off plus free shipping when they buy two or more pairs of prescription glasses at https://WarbyParker.com/MESSY— using our link helps support the show. #WarbyParker #ad
Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout.


