ID:IOTS - Infectious Disease Insight Of Two Specialists

Callum is reunited with Jame following their separation at ECCMID 2023. Callum shares some highlights including Archaea and their role in human health, Digitalisation within the microbiology lab and the ESCMID/IDSA interviewLinks to publications on Archaea:https://www.moissleichingerlab.com/projects/https://twitter.com/chmoei?lang=enDigitalisation and machine learning in microbiology presentation link: https://appliedmicrobiologyresearch.net/en/blog/keynote-by https://twitter.com/AppliedMicrobi2?s=20Carlos del Rio, president of the IDSAhttps://twitter.com/CarlosdelRio7?s=20 Register for the BIA Spring Meeting 2026 here!  Support the showWe are currently seeking more detailed feedback, please help us improve the podcast by giving your feedback here: https://forms.gle/yXTxeYQt1UKnUFGp7Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

This podcast explores the basics of beta-lactamase inhibitors, including their targets and classification. It discusses specific inhibitors like clavulanic acid and newer ones like Avabactam. The selection and use of inhibitors for different beta-lactamase enzymes are also covered, including the combination of Astraenam and Avobactam for hydrolysis treatment.

Jame and Callum are joined by the one and only Sara Dong of Febrile fame to look at the American Board of Internal Medicine's Infectious Disease Certification Exam.  Register for the BIA Spring Meeting 2026 here!  Support the showWe are currently seeking more detailed feedback, please help us improve the podcast by giving your feedback here: https://forms.gle/yXTxeYQt1UKnUFGp7Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Jame and Callum are joined by semi-recent FRCPath Microbiology part 1 exam passers Callum and Jame to discuss how best to prepare for this exam. This exam is sat by all infection trainees in the UK, as well as other health care professionals working in infection such as clinical scientists. Full revision resources notes available in the linked OneDrive folder below (if you can't access it let us know). Let us know once you pass! (Disclaimer: previous sentence for engagement purposes only, please do not let us know once you pass).  Register for the BIA Spring Meeting 2026 here!  Support the showWe are currently seeking more detailed feedback, please help us improve the podcast by giving your feedback here: https://forms.gle/yXTxeYQt1UKnUFGp7Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Jame and Callum are joined by Vin from Microbe Mail to discuss the management of Difficult to Treat Resistance (DTR) Gram negative infections in South Africa.If you haven't already check out Microbe mail for a high quality infection podcast linking the lab and clinical management.... wait that sounds familiar!Vin is a associate Professor in Clinical Microbiology at the University of the Witwatersrand, Johannesburg, South Africa and a practising clinical microbiologist with the National Health Laboratory Service. She is passionate about microbes (of course), antimicrobial resistance, antimicrobial stewardship, diagnostics, healthcare associated infections, fungal infections, One Health...let's just say it's a very long list!References:Metallo-β-lactamase resistance in Enterobacteriaceae is an artefact of currently utilized antimicrobial susceptibility testing methods Best practices: Appropriate use of the new β-lactam/β-lactamase inhibitor combinations, ceftazidime-avibactam and ceftolozane-tazobactam in South AfricaColistin Monotherapy versus Colistin plus Meropenem Combination Therapy for the Treatment of Multidrug-Resistant Acinetobacter baumannii Infection: A Meta-Analysis Register for the BIA Spring Meeting 2026 here!  Support the showWe are currently seeking more detailed feedback, please help us improve the podcast by giving your feedback here: https://forms.gle/yXTxeYQt1UKnUFGp7Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Jame and Callum are joined by recent FRCPath Microbiology part 2 exam passers Olly and Rob to discuss how best to prepare for the exam. This is the final exam required to qualify as a medical/clinical microbiologist in the UK. Full revision resources notes available on this notion page: https://idiots.notion.site/40-FRCPath-part-2-microbiology-78288c756979431fa82c6191ab3622f3 Register for the BIA Spring Meeting 2026 here!  Support the showWe are currently seeking more detailed feedback, please help us improve the podcast by giving your feedback here: https://forms.gle/yXTxeYQt1UKnUFGp7Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Discover a groundbreaking discussion on community-acquired pneumonia treatment, specifically the potential to safely shorten antibiotic use to just three days. The hosts delve into the importance of antibiotic stewardship and compare new findings with traditional eight-day regimens. They examine pneumonia risk scoring systems, advocating for better integration in healthcare. The conversation highlights the challenges of data-driven decision support, emphasizing the need for effective communication in clinical guidelines and practices.

Exploring the nuances of gram positive vs. negative bacteremia, differences in pathogenesis, management, and therapy. Delving into the complexities of bacteremia, immune responses triggered by exotoxins and endotoxins. Optimizing treatment with follow-up cultures and transitioning to oral therapy, including insights from the Sabato trial. Evolution of bacteremia management practices towards personalized treatment.

The rise and fall of Plazomicin reveals the harsh realities of antibiotic development. Explore the financial and regulatory hurdles that inhibit new antibiotic approvals. The innovative subscription model for pharmaceuticals may offer a solution, but what are the implications? Delve into the balance of cost and efficacy in antibiotic selection and the ongoing challenge of antibiotic resistance. The discussion emphasizes the importance of stewardship and invites listener support for reintroducing promising treatments like Plazomicin.

In this episode, the hosts delve into the complexities of urinalysis for UTI diagnosis, discussing the challenges of interpreting test results and the implications of reducing unnecessary tests in healthcare. They highlight the reflex nature of urine analysis, caution against overtreatment of asymptomatic patients, and emphasize the importance of accurate interpretation for optimal patient outcomes.