Big Brains

There are far more scientists in today’s world, and they’re publishing research papers at a much faster pace. However, all of this growth hasn’t translated to more scientific progress. As University of Chicago Professor James Evans argues, scientists are overloaded by the flood of research papers they have to read, which is causing them to cite the same few papers over and over again. This dilemma is leaving newly published papers with less of a chance to disrupt existing work. Evans directs the Knowledge Lab at UChicago, which is trying to reimagine the scientific process by providing better pathways for new scientific ideas to be shared with others. He explains how we can get back to advancing science again. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

The United States recently hit a grim milestone: More than 100,000 Americans died from drug overdoses between May 2020 and April 2021. The majority of those deaths were due to synthetic opioids, which have become more widely available in recent years. While medical interventions exist, the rise of opioid addiction has been difficult to prevent, let alone cure. Now, there could be a new promising solution: a vaccine, developed by Prof. Marco Pravetoni of the University of Washington, who leads the Center for Medication Development for Substance Use Disorders. The vaccine is currently in the first phase of clinical trials, being led by Prof. Sandra Comer of Columbia University, who directs the university’s Opioid Laboratory. Together, Pravetoni and Comer hope to provide a new pathway toward recovery from opioid addiction. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

As Vladimir Putin continues his invasion of Ukraine, Western nations have come together in unprecedented fashion to condemn his actions, in the form of economic sanctions against Putin and his Russian oligarchs. But how were these sanctions implemented so quickly, and what was the international legal infrastructure than enabled us to target the oligarch’s assets in the west? A major tool western nations have used to enact sanctions is called the Magnitsky Act. Two years ago, we interviewed the man responsible for the creation of this act: Bill Browder, CEO of Hermitage Capital Management and a University of Chicago alum. We think it’s worth re-airing that interview in the current context to get a deeper understanding of the sanctions against Russia, Putin’s regime and how a few brave people forged a pathway to hit him where he he’s weakest. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Solving problems like poverty, education inequality or discrimination require policy interventions that can scale, but they rarely do. Why do some scale, while others have little success? It's not luck, it's not skill, it's actually a scientific method—at least, that's how Prof. John List describes it. A world-renowned economist at the University of Chicago, List has helped scale some big policies and technologies as a former White House chief economist and the chief economist for both Uber and Lyft. Through his experience, he's observed a thing or two about what not to do. In his new book, The Voltage Effect: How To Make Good Ideas Great And Great Ideas Scale, List lays out five key factors that people should consider when thinking through any idea, policy or product. He explains how shifting from policy-based evidence to evidence-based policy can solve some of the world’s more pressing issues. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Big data has created a world of personalization. We have personalized medicine, personalized education, personalized advertising. Now, one University of Chicago Law School scholar is asking: Why not personalized law? In his new book, Personalized Law: Different Rules For Different People, Prof. Omri Ben-Shahar lays out the case for why our idea of equality under the law actually leads to unequal outcomes, and why we should use data and algorithms to tailor our laws to individual people. As he says: If one size fits all doesn’t work for shoes, why should it work for speed limits? Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Every year many of us set New Year’s resolutions, and almost none of us actually follow through on them. In a year when fulfilling our goals and resolutions feels more pressing than ever while our motivation may be at its lowest; let’s do what we do best: Turn to the research to get some concrete answers on how to follow through. Ayelet Fishbach is a professor at the University of Chicago Booth School of Business and the author of a new book, Get It Done: Surprising Lessons from The Science of Motivation. She is one of the leading experts on the research behind what keeps us motivated to complete our goals. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Prof. Jacqueline Stewart’s career has examined the histories of overlooked Black filmmakers and Black audiences. Last year, the University of Chicago film scholar Stewart won a prestigious MacArthur fellowship for “illuminating the contributions that overlooked Black filmmakers and communities of spectators have made to cinema’s development as an art form.” Stewart also serves as the host of Silent Sunday Nights on Turner Classic Movies and is chief artistic and programming officer at the Academy Museum of Motion Pictures. On this episode, Stewart explores the history of Black cinema and explains how preservation and archiving are not neutral acts, but contribute to how we contextualize and understand Black history. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

The race to cure cancer has been running a long time, but two University of Chicago scientists are working to bring it closer to the finish line. Thinking like engineers rather than doctors, Profs. Jeffery Hubbell and Melody Swartz of the Pritzker School of Molecular Engineering are bringing new approaches to the field of immunotherapy—and helping us rethink cancer research. Swartz has even developed what she calls a cancer ‘vaccine’—a way to train the immune system to recognize cancer cells as bad. By tinkering with the different parts inside our bodies, Swartz’s and Hubbell’s labs are searching for ways to utilize immunotherapy while eliminating its downsides. If their biggest ideas pass clinical trials, we could enter a new era of fighting not only cancer, but a host of other diseases. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

There’s something strange happening with violent crime in America. Incidents are reaching levels they haven’t hit in decades, and nobody seems to know why. But, to go even deeper, what causes violent crime to happen at all—and what can be done to help prevent it? Prof. Jens Ludwig is an economist and urban policy expert at the University of Chicago and the Pritzker Director of the Crime Lab, which partners with policymakers in major cities across the country to help reduce gun violence and reduce the harms of the criminal justice system itself. Using randomized control trials and massive data sets, he and his colleagues have been able to find demonstrable policy strategies and community programs for preventing crime. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

If you could have any superpower, what would it be? Most people say they’d want to read minds. But Prof. Nicholas Epley of the University of Chicago Booth School of Business says you already have that power: You just need to use it. We took some time off to enjoy the holiday and our families. And, like many of you here in the vaccine phase of the pandemic, we really cherished speaking to and connecting with people in person again. Which reminded us of an episode we did years ago about a simple but powerful idea…that talking to strangers can make you healthier. We want to reshare that episode with you this week, and we’ll be back with a brand new episode next week! Thanks for listening! Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.