
Simeon George
CEO and managing partner of venture firm SR One (SR1) and co-founder of SR1 Capital Management after its spinout from GSK; experienced investor and founder involved in notable biotech deals and company creation.
Best podcasts with Simeon George
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Mar 23, 2026 • 1h 6min
Episode 37: SR One's Simeon George
Simeon George, CEO and co-founder of SR One and physician-turned-investor, led its spinout from GSK and builds biotech companies. He recounts SR One’s transition to independence, how they pick and reserve capital for bets across modalities and indications, and the role of collaboration and syndication in sourcing and scaling ventures. He also touches on global sourcing, selective tech bets, and how AI fits into R&D.

Feb 20, 2025 • 31min
Ep. 78 - Biotech’s New Normal: SR One’s Simeon George on Adapting to Market Constraints
Simeon George, CEO and managing partner of SR One and biotech investor/founder, gives a candid take on adapting to a tougher capital market. He discusses valuation realism, prioritizing programs and when to pivot. He outlines proactive sourcing, China’s accelerating ecosystem, and building transatlantic companies. Practical strategy and capital discipline are central themes.


