Sean MacDonald
Biotech executive and CEO of Kinova Therapeutics with over 20 years of industry experience in strategy and development, leading GPCR-focused drug discovery and a clinical pipeline targeting immuno-oncology and inflammation.
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Mar 6, 2026 • 34min
Reversing tumor immunosuppression with next-gen GPCR modulation
Sean MacDonald, biotech executive and CEO of Kinova Therapeutics with 20+ years in GPCR drug discovery. He discusses Kinova’s GPCR-modulating platform and clinical programs for reversing tumor immunosuppression and treating inflammation. Conversation covers the company rebrand, Series B funding, lead programs (anti-CCR8, PAR2, EP4), partnering strategy, and trends shaping oncology and drug discovery.
