
Robert G. Holloway
Neurologist and palliative care clinician at the University of Rochester School of Medicine and Dentistry, holding the Edward and Alma Vollertsen Rykenboer Chair and author of the Continuum article on managing prognostic uncertainty.
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Jan 28, 2026 • 23min
Managing Prognostic Uncertainty in Neurologic Disease With Dr. Robert G. Holloway
Robert G. Holloway, neurologist and neuropalliative clinician at the University of Rochester, discusses prognostic uncertainty in neurologic illness. He outlines types of uncertainty, how system gaps and existential fear affect patients, and practical communication approaches like best/worst/most-likely framing. He urges embracing uncertainty, building believable narratives, and using family input to support adaptive coping.


