Neeta Somaiah

Professor and chair of the Sarcoma Medical Oncology Group at The University of Texas MD Anderson Cancer Center, specializing in sarcoma care and research with expertise in molecular drivers and treatment sequencing in GIST.

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Mar 20, 2026 • 26min

S16 Ep31: ctDNA Testing At Progression May Help Detect Resistance and Guide Sequencing in GIST: With Drs Jonathan Trent, MD, PhD, and Neeta Somaiah, MD

Neeta Somaiah, MD, professor and chair of Sarcoma Medical Oncology at MD Anderson, discusses molecular drivers and sequencing in GIST. They explore how ctDNA testing at progression can uncover secondary KIT resistance mutations. Short talks cover rarity of GIST, importance of specialist centers, mutation-informed treatment choices, and emerging combinations to tackle resistant clones.

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