Michael Wells
Postdoctoral fellow and first author on the study using human iPSC-derived neural progenitor cells and cerebral organoids to investigate Zika virus infection mechanisms.
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Dec 20, 2016 • 1h 15min
Ep. 81: “Organoids and Zika” Featuring Drs. Kevin Eggan and Michael Wells
Dr. Kevin Eggan, Harvard professor who models neurological disease, and Dr. Michael Wells, postdoc who built iPSC-derived organoid Zika models, discuss organoids used to probe how Zika infects developing brain tissue. They cover CRISPR knockouts like AXL, redundant entry pathways, innate immune roles, and whether Zika will become endemic or be controlled. Practical lab approaches and long-term risks are debated.
