Matthew Semler
Physician, researcher, and professor of medicine, anesthesiology, and informatics who directs pragmatic critical care research and served as senior author on the RSI trial.
Best podcasts with Matthew Semler
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Jan 21, 2026 • 1h 35min
RSI Trial Deep Dive
Nicole Acquisto, clinical research pharmacist and emergency medicine professor, and Matthew Semler, physician-researcher leading pragmatic critical care trials, dissect the RSI trial comparing ketamine and etomidate. They review prior evidence, study design and logistics, surprising hemodynamic findings, subgroup signals in sepsis, and implications for practice and future research. Short, clear, and focused discussion.
