Marie E McDonnell

Endocrinologist and director of the diabetes program at Brigham and Women's Hospital who specializes in managing complex diabetes in cancer patients and collaborates with oncology teams.

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Mar 28, 2026 • 1h 16min

Diabetology in Breast Cancer — Managing Hyperglycemia in Patients with Breast Cancer Receiving Agents Targeting the PI3K/AKT/PTEN Pathway

Professor Giuseppe Curigliano, oncology professor with international trial experience; Dr Hope S Rugo, medical oncologist experienced in breast cancer therapeutics; Dr Marie E McDonnell, endocrinologist specializing in diabetes in cancer patients. They discuss hyperglycemia linked to PI3K/AKT/PTEN inhibitors. Topics include continuous glucose monitoring, steroid-related spikes, timing and incidence of drug-induced hyperglycemia, and practical monitoring plus management strategies.

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