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Manish Shah
Medical oncologist and co-chair of the ASCO guideline update on immunotherapy and targeted therapy for advanced gastroesophageal cancer, experienced in clinical research and guideline development for GI malignancies.
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Feb 26, 2026
• 29min
Immunotherapy and Targeted Therapy for Advanced Gastroesophageal Cancer Guideline Update
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Dr. Manish Shah, medical oncologist and guideline co-chair with expertise in GI clinical research, and Dr. Lakshmi Rajdev, medical oncologist and guideline co-chair skilled in interpreting trial evidence, discuss updated recommendations for immunotherapy and targeted therapy in advanced gastroesophageal cancers. They cover biomarker-driven testing, first-line choices for adenocarcinoma and squamous cancers, CLDN18.2 and HER2 advances, and upcoming trials that may change practice.
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