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Laura Huppert
Academic medical oncologist at UCLA specializing in breast cancer, invited as an expert guest to review and interpret practice-changing SABCS 2025 trial results in early-stage hormone receptor–positive breast cancer.
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Dec 22, 2025
• 16min
Early HR+ Disease SABCS 2025 Practice Changing/Informing Highlights: ALTTO, lidERA, NATALEE
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Dr. Laura Huppert, an academic medical oncologist at UCLA, joins to unpack groundbreaking findings from the SABCS 2025 conference on early-stage hormone receptor-positive breast cancer. She delves into the ALTTO study, highlighting the advantage of aromatase inhibitors over tamoxifen. The discussion then moves to the lidERA study, spotlighting the potential of giredestrant in improving invasive disease-free survival. Finally, insights from the NATALEE trial showcase the enduring benefits of ribociclib across various patient subgroups, reshaping treatment strategies.
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