Jeffrey Miller
Physician-scientist specializing in natural killer (NK) cell biology and therapeutics; deputy director at the Masonic Cancer Center with decades of clinical NK cell work and development of tri-specific NK cell engagers (TRIKES).
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Mar 17, 2026 • 59min
Episode: 83 - Patrick Baeuerle and Jeffrey Miller on T Cell and Immune Cell Engagement
Jeffrey Miller, physician‑scientist advancing NK cell therapies and tri‑specific NK engagers. Patrick Baeuerle, biotech entrepreneur behind T‑cell bispecifics and peptide‑MHC work. They compare T cell and NK engagers to CAR T approaches. Topics include conditional tumor selectivity, IL‑15 and NK activation, peptide‑MHC targeting, manufacturing and clinical strategies, and use in MRD and neoadjuvant settings.
