
James Yoder
Founder and CEO of OpenBench with a background in statistics, data science, and applied machine learning, leading efforts in success-driven computational hit discovery and ultra-large virtual screening.
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Feb 11, 2026 • 54min
Success-Driven Drug Discovery with OpenBench CEO James Yoder
James Yoder, Founder and CEO of OpenBench and former statistician turned ML leader, describes a success-driven approach that charges only for validated hits. He discusses ultra-large virtual screening, computational pipelines for binding prediction, and how data flywheels and active learning improve hit discovery. He also explains risk-sharing collaborations and real-world case studies.


