
James Waldron
Reporter for Fierce Biotech who led the 2025 clinical trial flops report, providing analysis of major trial failures and industry trends in drug development.
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Feb 13, 2026 • 20min
What were the biggest clinical trial flops of 2025?
James Waldron, Fierce Biotech reporter who led the 2025 clinical trial flops report, breaks down high-profile late‑stage failures. He spotlights why big pharma dominated the list. He walks through notable misses from Novo Nordisk and Sanofi, mixed COPD readouts, and surprising wins and losses across rare-disease programs.


