Dr. James Caridi, an expert in CO2 angiography, discusses the benefits of using CO2 for angiography including solubility and low viscosity. He talks about CO2 angiography for difficult to access vasculature, mesenteric angiography, and improving sensitivity for detection of GI bleeds. Non-vascular uses for CO2 angiography are also explored, along with a technique for imaging with CO2 without wire access. Safety principles, CO2 delivery systems, and the advantages of CO2 in interventional radiology procedures are discussed.