Franciska de Beer
Researcher and PhD candidate at the Center for Clinical Neuroscience and Cognition (University Medical Center Groningen) and first author on HAMLETT-OPHELIA Consortium publications exploring first-episode psychosis, antipsychotic tapering, dopamine supersensitivity, and sex differences in treatment outcomes.
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Apr 3, 2026 • 1h 12min
Psychiatrist Effect in First-Episode Psychosis: HAMLETT Study, Antipsychotic Tapering, Dopamine Supersensitivity & Sex Differences with Franciska de Beer
Franciska de Beer, researcher and PhD candidate focused on first-episode psychosis, discusses psychiatrist-driven outcome differences and why clinicians explain about 10% of symptom and functioning variance. She covers antipsychotic tapering versus maintenance, dopamine supersensitivity after strong D2 blockers, tapering strategies to avoid rebound, and sex- and menopause-related drug level differences.
