Frances H. Arnold
Nobel Prize–winning chemical engineer and Caltech professor known for pioneering directed evolution to create new enzymes with broad applications in chemistry, agriculture, and industry.
Top 3 podcasts with Frances H. Arnold
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146 snips
Oct 11, 2025 • 57min
168. Chemistry, Evolved
Frances Arnold, a Nobel Prize-winning chemical engineer at Caltech, revolutionized enzyme creation through directed evolution, a method mimicking natural selection. She discusses the intricate world of enzymes, their critical roles, and how her insights transformed industries from agriculture to biofuels. Arnold shares her journey from skepticism to acceptance in the tech world, emphasizing the importance of intuition and art in science. She also explores innovative pest control using insect pheromones and envisions a future where microbes create sustainable materials from CO2.
13 snips
Mar 3, 2026 • 30min
The Evolution Of An Enzyme Engineer Who Changed Chemistry
Dr. Frances Arnold, Nobel-winning enzyme engineer and Caltech professor who invented directed evolution, talks about harnessing evolution to retool enzymes. She explains how screening and libraries reveal unexpected functions. She imagines AI plus evolution encoding bespoke chemistry and discusses real-world work on TB drugs and PFAS cleanup.
Oct 3, 2018 • 4min
Nobel in Chemistry for New and Useful Chemical Entities via Evolutionary Principles
Chemistry Nobel laureates Frances H. Arnold, George P. Smith, and Gregory P. Winter discuss their revolutionary work in harnessing the power of evolution to create new chemical entities with useful properties.
