Farshid Guilak

Farshid Guilak, the Mildred Simon Professor of Orthopedic Surgery and Director of Research at Shriners Hospital, shares insights from his distinguished research career. He delves into innovative advancements in arthritis treatment and the iterative nature of cartilage regeneration. The conversation highlights the impact of mentorship in biomedical engineering and celebrates resilience in research. Additionally, he emphasizes the importance of work-life balance and personal energizers to avoid burnout, making for an engaging and thought-provoking discussion.

Dr. Farshid Guilak, a Washington University orthopaedics professor who develops stem-cell–based therapies for osteoarthritis. He discusses differences between osteoarthritis and rheumatoid arthritis. He explores obesity, diet, and post-traumatic risks to joints. He describes engineering mesenchymal stem cells with CRISPR circuits for targeted anti-inflammatory delivery and local versus systemic treatment strategies.