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David Fajgenbaum

Doctor and professor at the University of Pennsylvania. Survived idiopathic multicentric Castleman disease by finding his own cure and now uses AI to find treatments for rare diseases.

Top 10 podcasts with David Fajgenbaum

Ranked by the Snipd community
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626 snips
Nov 3, 2025 • 1h 59min

Using Existing Drugs in New Ways to Treat & Cure Diseases of Brain & Body | Dr. David Fajgenbaum

Dr. David Fajgenbaum, a physician-scientist and founder of EveryCure, shares his remarkable journey from battling Castleman's disease to pioneering drug repurposing. He reveals how existing medications, like aspirin and Viagra, can treat unexpected conditions. David emphasizes the importance of mindset in recovery and discusses innovative methods, including AI, to find effective treatments for diseases once deemed untreatable. His insights highlight the urgent need for collaboration between patients and medical professionals to explore novel therapies.
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372 snips
Feb 20, 2026 • 52min

664. Are Thousands of Medical Cures Hiding in Plain Sight?

Chris Snyder, economist at Dartmouth who designs market incentives; Heather Stone, FDA policy analyst who built the CureID registry; David Fajgenbaum, physician-scientist who survived Castleman disease and leads EveryCure. They explore drug repurposing, AI and knowledge graphs to match drugs to diseases, crowdsourced registries for real-world cases, and economic pull incentives to make trials and generic repurposing viable.
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126 snips
Aug 22, 2025 • 1h 2min

The Medical Matchmaking Machine

David Fajgenbaum, a doctor and professor at the University of Pennsylvania, shares his incredible journey of surviving idiopathic multicentric Castleman disease by finding his own cure. He discusses the flaws in current drug discovery processes and introduces his AI-driven tool that aims to connect untreatable diseases with potential treatments. The conversation highlights the challenges of navigating pharmaceuticals, the importance of personalized care, and the ethical implications of using technology in medicine, particularly in life-or-death situations.
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114 snips
Sep 26, 2025 • 32min

How do you turn hope into action? A doctor and a public health expert answer | David Fajgenbaum and Celina de Sola

David Fajgenbaum, an immunology researcher who overcame Castleman disease, and Celina de Sola, a public health expert from El Salvador, share insights on transforming hope into actionable change. They discuss their missions to repurpose drugs and address trauma in communities. David's AI-driven approach aims to match existing drugs with new diseases, while Celina highlights the importance of trauma-informed systems in policing. Together, they reveal how to scale impact through local engagement, humility, and the power of productive hope.
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95 snips
Feb 28, 2026 • 30min

What to do when you’re told there’s nothing left to try | David Fajgenbaum and Kiah Williams

Kiah Williams, a social entrepreneur who founded Serum to expand medicine access. David Fajgenbaum, a physician-scientist who repurposes drugs and leads EveryCure. They discuss turning hope into action through small, practical steps. They share stories of overcoming medical crisis and economic hardship, grassroots advocacy, building supportive teams, and actionable strategies to create change.
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85 snips
Mar 25, 2025 • 40min

ReThinking: How David Fajgenbaum saved his own life — and thousands of others

David Fajgenbaum, a physician-scientist who defied death at 25 by repurposing a drug to save his own life, shares his remarkable journey. He discusses the potential of AI in drug discovery and how his nonprofit, EveryCure, aims to unlock existing medicines for various diseases. The conversation dives into the emotional toll of illness and the importance of resilience and innovation in medical research, as well as the need for a mindset shift in the pharmaceutical industry to prioritize affordable treatments for rare diseases.
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67 snips
Mar 25, 2025 • 40min

How David Fajgenbaum saved his own life — and thousands of others

David Fajgenbaum, a physician scientist at Penn, faced death at 25 from Castleman's disease but miraculously saved himself by repurposing a drug. He founded Every Cure to help others unlock the potential of existing medications. In this discussion, he shares the building blocks of resilience and the disincentives in drug development. They also delve into how AI is revolutionizing the identification of new treatments and the importance of innovative partnerships between nonprofits and pharmaceutical companies in the fight against rare diseases.
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58 snips
Sep 8, 2025 • 16min

How nearly dying helped me discover my own cure (and many more) | David Fajgenbaum

David Fajgenbaum, a physician-scientist and co-founder of the nonprofit Every Cure, shares his incredible story of turning a near-death experience from a rare disease into a mission to save others. He reveals how he discovered a life-saving drug originally intended for a different condition. David discusses the innovative use of AI to uncover new treatments and the challenges faced in securing funding for his cause. His journey highlights the power of collaboration in healthcare and his drive to transform personal pain into a purpose that impacts many.
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41 snips
Oct 8, 2025 • 1h 8min

David Fajgenbaum on drug repurposing, AI, and saving his own life

David Fajgenbaum, a physician-scientist and rare-disease advocate, shares his inspiring journey from receiving last rites to founding EveryCure. He discusses life-saving drug repurposing, including a treatment he found for his own Castleman disease. Delving into the integration of AI in healthcare, David explores how it can accelerate diagnoses and treatments while addressing ethical concerns. With tales of resilience and innovation, he highlights the potential for faster medical discoveries and a future where existing drugs can treat a multitude of conditions.
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29 snips
Nov 26, 2025 • 1h 33min

David Fajgenbaum (on repurposing medicine)

David Fajgenbaum, an immunology researcher and author of "Chasing My Cure," shares his incredible journey of battling Castleman disease, where a promise to his late mother pushed him toward medicine. He discusses his near-death experiences and the breakthrough moment of discovering off-label drugs that led him to remission. Fajgenbaum also highlights his mission with EveryCure, using AI to repurpose existing medicines for other inflammatory diseases. With stories of miraculous drug repurposing, he aims to inspire hope and action in medical research.

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