David Dismuke
Chief Technical Officer at Forge Biologics with extensive expertise in AAV bioprocessing and GMP production, leading platform approaches for scalable AAV manufacturing and process development.
Best podcasts with David Dismuke
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Feb 12, 2026 • 39min
EP 226: Scaling AAV gene therapy: Engineering delivery, safety, and cost with David Dismuke of Forge Biologics and Steven Gray of UT Southwestern
Steven Gray, a pediatric professor engineering AAVs for CNS delivery, and David Dismuke, CTO scaling GMP AAV manufacturing, discuss translating AAV from lab to industry. They cover capsid engineering for brain delivery, manufacturing workflows and analytics, full versus empty particle impacts on safety, and how scale and platform choices could cut costs and enable next‑gen gene editing.
