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Christoph Thaiss
Assistant professor of pathology and core investigator at the ARC Institute whose lab studies gut–brain interactions; senior author of the Nature study linking age-related microbiome changes to memory decline in mice.
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Mar 19, 2026
• 43min
Could boosting gut–brain communication prevent memory loss? A tale of microbes, memory, and our internal senses | Christophe Thaiss
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Christoph Thaiss, assistant professor and ARC Institute investigator studying gut–brain interactions. He discusses how age-related microbiome shifts can blunt internal bodily signals and alter vagus nerve communication. Conversations cover experiments linking aged microbes to memory loss in mice, identification of a culprit bacterium, inflammatory pathways that mute vagal signaling, and potential therapies like vagal stimulation and drugs.
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