
Bryan Pellegrino
CEO of LayerZero Labs and featured guest discussing LayerZero’s Zero blockchain, institutional adoption, asset issuance, and interoperability; shares firsthand perspective on product and strategy.
Top 10 podcasts with Bryan Pellegrino
Ranked by the Snipd community

20 snips
Jan 7, 2026 • 30min
The Obsession That Destroys Startups (with LayerZero CEO)
Bryan Pellegrino, Cofounder and CEO of LayerZero, a blockchain interoperability project, discusses the evolution of crypto into a multichain world. He shares insights from his poker background, emphasizing the importance of competition and conviction. Bryan reveals valuable lessons from Elon Musk on focusing product development over external advice. The conversation also covers the necessity for self-disruption and the challenges founders face when scaling leadership. With anecdotes and practical strategies, he guides aspiring entrepreneurs in navigating the startup landscape.

12 snips
Feb 12, 2026 • 1h 5min
Building The Interoperable Future Of Crypto With LayerZero
Simon Baksys, Director of Business Development at LayerZero, ex-Google Cloud partnership lead. Bryan Pellegrino, Co-founder and CEO, former pro poker player turned crypto and ML entrepreneur. They discuss why interoperability matters across blockchains. They cover Layer 2 trade-offs, cross-chain messaging vs bridges, stablecoins’ role in global finance, and AI agents driving high-volume microtransactions.

11 snips
Nov 29, 2021 • 51min
LayerZero Labs: Building the Future of Cross-chain, LayerZero Protocol, and Solving the Bridging Trilemma with Stargate
Delphi Digital’s cross-chain experts, Avi Zurlo and Can Gurel sit down with co-founders, Bryan Pellegrino (CEO) and Ryan Zarick (CTO), of LayerZero Labs, a trustless omnichain interoperability protocol. They discuss building the future of cross-chain communication, solving the bridging trilemma, and Stargate, a cross-chain liquidity network.
Show Notes:
(00:00:00) – Introduction.
(00:00:47) – Guests’ take on the future of blockchains.
(00:03:25) – What is LayerZero?
(00:09:00) – Expected oracle-relayer combinations.
(00:12:51) – The architecture and efficiency of the ultra light node.
(00:15:06) – The opportunities for on-chain generic messaging.
(00:18:01) – Overview of Stargate.
(00:23:00) – The bridging trilemma.
(00:27:46) – Stargate’s user experience.
(00:33:57) – Instant guaranteed finality on Stargate.
(00:37:22) – Chains that Stargate will support.
(00:40:30) – LayerZero and Stargate tokens?
(00:45:23) – LayerZero’s biggest challenge.
(00:49:18) – How people can get involved with LayerZero.
(00:51:18) – Closing thoughts.
Social links:
Bryan’s Twitter
Ryan’s Twitter
LayerZero Labs Twitter
Stargate Twitter
Resources:
Delphi Podcast Summaries
LayerZero Website
LayerZero Blog
The Bridging Trilemma
More
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Disclosures: This podcast is strictly informational and educational and is not investment advice or a solicitation to buy or sell any tokens or securities or to make any financial decisions. Do not trade or invest in any project, tokens, or securities based upon this podcast episode. The host and members at Delphi Digital may personally own tokens or art that are mentioned on the podcast. Our current show features paid sponsorships which may be featured at the start, middle, and/or the end of the episode. These sponsorships are for informational purposes only and are not a solicitation to use any product, service or token. Delphi’s transparency page can be viewed here.

Feb 27, 2024 • 1h 35min
Debating the Multichain End State: Service Providers vs Immutable Protocols | S7 E4 | Bryan Pellegrino
The podcast delves into the debate of multi-chain future, focusing on infrastructure layers vs service providers, censorship resistance, and security tradeoffs. They discuss modular architecture, native vs wrapped assets, and interoperability needs. The conversation explores the balance between efficiency and security, security vs liveness in transactions, and enhancements in Uniswap protocol. They also touch on the future of interoperability, asset trading, and maintaining protocol neutrality for security.

Feb 23, 2026 • 1h 39min
Zero Just Made Blockchains 100x Better | Bryan Pellegrino & Raz Zarick
Raz Zarick, CTO and ZK expert who built Zero’s technical architecture. Bryan Pellegrino, CEO and cross-chain builder leading LayerZero’s move to an L1. They discuss Zero’s origin, why its architecture claims a 100x breakthrough, separating execution from verification, achieving massive TPS, and the roadmap and product zones for 2026.

Feb 20, 2026 • 1h 24min
Uneasy Money: Why Peter Steinberger and Non-Crypto People Hate the Crypto Mob
Bryan Pellegrino, CEO of LayerZero Labs — brief bio: builder behind LayerZero and the Zero blockchain. He unpacks Base leaving the OP Stack, Zora’s jump to Solana, why L2s may become independent L1s, institutional motives for owning rails, and how AI agents and open source reshape security and developer dynamics.

Nov 19, 2025 • 55min
The Next Chapter For EigenZero | Bryan Pellegrino & Sreeram Kannan
Sreeram Kannan, a crypto-economic security expert and co-creator of Eigenlayer, teams up with Bryan Pellegrino from LayerZero Labs to unveil EigenZero. They discuss decentralized verifier networks (DVNs) and how they enhance cross-chain messaging. The duo explains the insured-bridge concept and its implications for security and throughput. Developers are encouraged to leverage EigenCloud’s capabilities for scalable solutions, while AI agents are explored for verifying model correctness. Insights on adoption metrics and future roadmap priorities round out their fascinating conversation.

Mar 17, 2025 • 48min
Interoperable Onchain Finance Ft. LayerZero CEO Bryan Pellegrino
Bryan Pellegrino, CEO of LayerZero, delves into the world of blockchain interoperability and its pivotal role in finance. He discusses the complexities and security challenges in multi-chain asset issuance, and how LayerZero simplifies cross-chain transactions. The rise of multi-chain stablecoins like USDT Zero is also explored, highlighting the critical nature of being first in new blockchain ventures. The conversation concludes with intriguing insights on the intersection of AI and cryptocurrency, revealing the future potential of these converging technologies.

Jun 21, 2024 • 54min
UNCHAINED: LayerZero Fought the Sybils and Airdropped Its Token. Did the Team Win?
Founder Bryan Pellegrino discusses LayerZero's ZRO token launch, controversies, anti-Sybil campaign challenges, mandatory donation to Protocol Guild, and reflections on airdrop distribution strategies. The episode explores the complexities of detecting Sybil accounts, community response, security measures, and recent crypto developments.

Jun 21, 2024 • 57min
LayerZero Fought the Sybils and Airdropped Its Token. Did the Team Win? - Ep. 664
In this engaging conversation, Bryan Pellegrino, cofounder and CEO of LayerZero Labs, dives into the challenges of their ambitious anti-Sybil campaign during their recent airdrop. He discusses the creative strategies employed to combat fraudulent accounts, revealing over a million fake entries. Bryan shares insights on the self-reporting option for Sybil attackers and reflects on lessons learned, including the imposition of a mandatory donation to the Protocol Guild. He also tackles the future of airdrops and explores alternatives to improve user participation.


