
Andy Perfors
Cognitive science professor who came out as trans and writes about uncertainty; appears in the episode as an interviewed mentor discussing living with ambiguity and the personal effects of hormone therapy.
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Nov 4, 2025 • 47min
FEATURE | Unknown Unknowns
Lio Wong, writer and cognitive scientist who narrates a first-person search for answers about starting testosterone. Andy Perfors, cognitive science professor and mentor who reflects on living with ambiguity after coming out as trans. They explore parsing limited medical evidence, ‘theoretical risk’ in guidelines, personal experiments with hormones, and choosing lived experience amid scientific uncertainty.


