Alysson Muotri
Researcher who grows human brain organoids to study neurodevelopment and evolutionary differences, used here to probe effects of lead exposure on archaic versus modern human genes.
Top 3 podcasts with Alysson Muotri
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Oct 30, 2025 • 45min
Detecting the acidity of the ocean with sound, the role of lead in human evolution, and how the universe ends
Join Paul Voosen, a dedicated climate reporter, as he unveils a groundbreaking acoustic method to detect ocean acidification, revealing the hidden effects of rising CO2 levels. Alysson Muotri, a researcher of brain organoids, explains how studying ancient and modern gene responses to lead exposure may offer insights into human evolution and resilience. Plus, Katie Mack, a theoretical cosmologist, shares fascinating theories about the universe's ultimate fate—including heat death and vacuum decay—provoking thoughts on our place in an ever-evolving cosmos.
Nov 27, 2025 • 1h 12min
Brain Scientist On AI: You Aren’t Ready For What’s About To Happen | Dr. Alysson Muotri
Dr. Alysson Muotri, a leading geneticist and neuroscientist, dives into the groundbreaking world of brain organoids. He shares insights on how these mini-brains could revolutionize our understanding of neurological diseases and even influence AI development. Topics include organoids as personalized disease avatars, the ethical ramifications of merging biology with computation, and the potential for organoid intelligence to navigate complex tasks. Muotri’s work opens fascinating doors to the future of medicine and artificial intelligence.
Apr 25, 2017 • 1h 10min
Ep. 90: “Eating Disorder Gene” Featuring Dr. Alysson Muotri
Dr. Alysson Muotri, a UC San Diego professor who models neurological disorders with human iPS cells, discusses creating a cellular model of anorexia nervosa. He covers using patient-derived neurons, transcriptomics that flagged TACR1, and challenges of studying psychiatric conditions in a dish. He also talks about organoids, chimeras, and the need for better brain tissue resources.
