What You Need to Know About the #1 Leading Cause of Death in Women

The Menopause Mastery Show | Understanding Women's Cardiac Health In Menopause | Episode 272 with John Osborne, MD, PhD, FACC, FNLA

🌱 Welcome to The Menopause Mastery Show! In this episode, Dr. Betty Murray welcomes cardiologist Dr. Peter Osborne to discuss menopause as a major cardiovascular transition, and how women are often misassessed using a male-centered model. They discuss women's higher rates of missed or atypical heart attack symptoms (fatigue, shortness of breath, nausea) and conditions more common in women such as microvascular disease, Takotsubo ("broken heart") cardiomyopathy, and SCAD. Osborne criticizes stress tests and frequent unnecessary caths, arguing prevention should start with imaging—at least a calcium score at ~40, and ideally cardiac CT with AI to detect and quantify soft and calcified plaque, track progression, and guide treatment. They cover menopause-related lipid shifts, low HRT use and recent FDA label changes, and key labs including Lp(a) (genetic; estrogen lowers it; Horizon trial with pelacarsen) and ApoB targets for plaque reversal.

🩺 Discover the untold truths about menopause and heart health in this important installment of The Menopause Mastery Show! Join Dr. Betty and Dr. Osborne as they dive into how women's cardiovascular health is more than you think.

To connect with Dr. Osborne: https://clearcardio.com/

You Tube Channel: @ClearCardio⁩

00:00 Menopause Heart Risk 00:38 Why Women Get Missed 03:47 Heart Attack Symptoms 08:28 Microvascular Disease 12:59 Stress Heart Syndromes 16:15 Estrogen and Vessels 19:41 Lipoprotein A Explained 25:29 ApoB Better Marker 29:37 Why Imaging Matters 36:17 Stress Tests Limitations 40:19 Calcium Score Basics 41:31 Calcium Score Basics 42:10 Soft Plaque Blind Spot 43:55 Cardiac CT Full Picture 45:02 Mammogram Biopsy Analogy 46:03 AI Plaque Tracking 47:45 Egg Plaque Visual 48:58 Start With Imaging 51:36 Women Menopause Risk 52:50 Screening Magic Wand 58:34 Donut Wall Plaque 59:18 Staging And Prevalence 01:02:35 Treatment Tools Repatha 01:05:05 Cholesterol Too Low 01:10:54 Preventive Cardiology Path 01:13:43 Clear Cardio Access 01:15:30 Hypertension Parking Lot 01:17:00 Eliminate Heart Disease 01:18:03 Resources And Farewell

Connect with Dr. Betty Murray: Betty Murray Website: https://www.drbettymurray.com/ Instagram: https://www.instagram.com/drbettymurray/

Like, comment, and subscribe on YouTube: ⁨@drbettymurray⁩

Links: The Fierce Female Method for Longevity (Dr. Betty's book): https://fierce.hormoneshelp.com/ Menrva Telemedicine: https://gethormonesnow.com/ Living Well Dallas: https://www.livingwelldallas.com/ More from the Podcast: Subscribe to #MenopauseMastery → https://www.youtube.com/channel/UCwONPdSvb2-YYY74VhD-XBw Apple Podcasts → https://podcasts.apple.com/us/podcast/menopause-mastery/id1607369247 Spotify → https://open.spotify.com/show/0tNsjm32CZNXSgSFEwS3uH

Thank you for listening to Menopause Mastery. Empowering your health journey, one episode at a time.

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