Dwarkesh Podcast Steve Hsu - Intelligence, Embryo Selection, & The Future of Humanity
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Aug 23, 2022 
In this engaging discussion, Steve Hsu, a theoretical physics professor and co-founder of Genomic Prediction, dives into the revolutionary world of embryo selection and its implications for human health and intelligence. He examines how advanced genomics can enhance IVF outcomes and the ethical dilemmas surrounding genetic engineering. Hsu also explores the historical factors affecting human evolution and the societal impact of genetic choices on parenting and reproduction. With thought-provoking insights, he navigates the future of humanity shaped by science and technology.
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Evolution and Trait Optimization
- Human traits are often controlled by many genes, allowing for variation without breaking core mechanisms.
- Evolution hasn't fully optimized traits due to changing environments and the complexity of high-dimensional fitness landscapes.
Additive Genetic Architecture
- The additive nature of genetic architecture means traits are controlled by the sum of many small genetic effects.
- This modularity allows independent variation of many traits, enabling targeted genetic engineering.
First-Mover Advantage and Future Competition
- Genomic Prediction has a first-mover advantage through established relationships with IVF clinics.
- However, companies with more data and better AI could potentially develop superior predictors in the future.