
Big Technology Podcast The Hidden Science Behind Brain-Computer Interfaces — With Sally Adee
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Aug 27, 2025 Sally Adee, a science journalist and author of 'We Are Electric,' dives into the fascinating world of brain-computer interfaces (BCIs). She explores how electrical impulses drive our thoughts and movements, the groundbreaking potential of BCIs for disabled individuals, and the ethics surrounding pleasure-enhancing technology. Adee discusses innovative topics like limb regrowth in tadpoles, cancer cells that disrupt electrical balance, and the future challenges of keeping implants functional. Tune in for an electrifying journey through science and ethics!
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Past Abuse Of Pleasure Stimulation
- Historical experiments electrically stimulated pleasure centers and attempted behavior change in the 1960s.
- One infamous case tried to alter sexual orientation via stimulated reward pairing and failed, harming the field's reputation.
Habituation And Implant Longevity Limit Abuse
- Repeated artificial stimulation may lose effectiveness due to habituation.
- Implant lifetime is short now, so continuous pleasure stimulation would require repeated surgeries or replacements.
All Cells Carry Electrical Identities
- Non-neuronal cells also have characteristic membrane voltages linked to identity and development.
- Depolarized cells near zero mV (like stem cells) are more plastic and can become many cell types.

